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3t magnet

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The 3T magnet is a core component of magnetic resonance imaging (MRI) systems manufactured by GE Healthcare. It generates a strong and stable magnetic field of 3 Tesla, which is used to align and excite hydrogen protons within the body, enabling the generation of detailed images of internal structures and functions. The 3T magnet provides high-resolution imaging capabilities, allowing for more accurate clinical diagnoses and treatment planning.

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Lab products found in correlation

8 channel receiver only head coil, by GE Healthcare (2 mentions) 3t mri, by GE Healthcare (1 mentions)

8 protocols using 3t magnet

1

Automated Hippocampus-Amygdala Volume Ratio Calculation

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Brain MR images were acquired on a 3T magnet (GE) using an 8-channel receiver-only head coil. T1-weighted images were obtained using a 3D fast spoiled gradient-echo (FSPGR) sequence using the following parameters: oblique-axial orientation (plane passing through the anterior-posterior commissures), 1-mm isotropic, field of view 256×192×210mm, TR=7.9 ms, TE=3.0 ms, TI=450ms and Flip angle=20deg. Segmentation and surface reconstruction quality were assured by manual inspection of all raw brain MRI volumes, segmented volumes in three planes and pial as well as inflated volumes. Fourteen participants' brain MRI data failed this quality assurance and were removed from the analysis. Hippocampal, amygdala and intracranial volume measures are a standard output of the FreeSurfer 5.3.0 volumetric segmentation (Fischl et al., 2002 (link)). For this study, we derived a measure of total AH volume ratio by dividing total (i.e. left and right) amygdala volume by total hippocampus volume.
Walton E., Cecil C.A., Suderman M., Liu J., Turner J.A., Calhoun V., Ehrlich S., Relton C.L, & Barker E.D. (2017). Longitudinal epigenetic predictors of amygdala:hippocampus volume ratio. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 58(12), 1341-1350.
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2

Preoperative Brain MRI Assessment

Cited 1 time
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MR imaging was performed preoperatively on a 3T magnet (General Electric, Milwaukee, WI). Sequences obtained included conventional T1- and T2-weighted imaging, diffusion-tensor imaging (DTI), and gradient-echo (GRE) sequences, as well as MR spectroscopy of the basal ganglia. Our neuroradiologist (JM) reviewed postnatal, pre-operative brain MRI and scored MRIs according to the Magnetic Resonance Imaging Abnormality Scoring System used by Andropoulos et al.33 (link) This scoring system categorizes brain MRI abnormalities as (i) white matter injury (WMI) , (ii) infarction (INF), (iii) intraparenchymal hemorrhage (IPH), (iv) punctate lesions (PL), (v) lactate peak on MRS (lactate), (vi) intraventricular hemorrhage (IVH), (vii) subdural hemorrhage (SDH), or (viii) deep venous sinus thrombosis (DVST). Abnormalities in each category are given a score of 0-3 (0=none, 1=mild, 2=moderate, 3=severe) and weighted by a significance multiplier.33 (link) For WMI, INF, and IPH the significance multiplier is 3, for PL and lactate the significance multiplier is 2, and for IVH, SDH, and DVST the significance multiplier is 1. Scores used in the analysis are derived from summated scores of all categories after application of the significance multiplier.
Schlatterer S.D., Govindan R.B., Murnick J., Barnett S.D., Lopez C., Donofrio M.T., Mulkey S.B., Limperopoulos C, & du Plessis A.J. (2021). In Infants with Congenital Heart Disease Autonomic Dysfunction is Associated with Pre-Operative Brain Injury. Pediatric research, 91(7), 1723-1729.
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3

Multimodal Brain MRI Segmentation

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Brain MR images were acquired on a 3T magnet (GE, Chicago, IL) using an 8‐channel receiver‐only head coil (GE). T1‐weighted images were obtained using a 3D fast spoiled gradient‐echo sequence using the following parameters: oblique‐axial orientation (plane passing through the anterior–posterior commissures), 1‐mm isotropic, field of view 256 × 192 × 210 mm, TR = 7.9 ms, TE = 3.0 ms, TI = 450 ms and Flip angle = 20°. Segmentation and surface reconstruction quality were assured by manual inspection of all raw brain MRI volumes, segmented volumes in three planes and pial as well as inflated volumes. Fourteen participants’ brain MRI data failed this quality assurance and were removed from the analysis. Hippocampal, amygdala and intracranial volume measures are a standard output of the FreeSurfer 5.3.0 volumetric segmentation (Fischl et al., 2002). For this study, we derived a measure of total AH volume ratio by dividing total (i.e., left and right) amygdala volume by total hippocampus volume.
Walton E., Cecil C.A., Suderman M., Liu J., Turner J.A., Calhoun V., Ehrlich S., Relton C.L, & Barker E.D. (2017). Longitudinal epigenetic predictors of amygdala:hippocampus volume ratio. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 58(12), 1341-1350.
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4

High-Resolution 3T MRI Brain Scans

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All MRI scans were conducted using a 3T magnet (Sigma, GE Medical Systems, Waukesha, WI) using a circular polarized birdcage head coil. 3-D T1-weighted anatomical images were acquired using the spoiled gradient recall (SPGR) sequence (repetition time: 8.35 ms; echo time: 3.27 ms; total acquisition time: 7 min; flip angle: 12°; field of view: 24 cm; image matrix: 512×512, slice thickness: 1 mm, voxel size of 0.47×0.47×1 mm3, number of slices: 156 sagittal slices).
Qiu H., Li X., Zhao W., Du L., Huang P., Fu Y., Qiu T., Xie P., Meng H, & Luo Q. (2016). Electroconvulsive Therapy-Induced Brain Structural and Functional Changes in Major Depressive Disorders: A Longitudinal Study. Medical Science Monitor : International Medical Journal of Experimental and Clinical Research, 22, 4577-4586.
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5

High-Resolution 3T MRI Brain Acquisition

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The MRIs were acquired on a 3-T magnet (GE Healthcare), using an 8-channel, receiver-only head coil. The T1-weighted images were obtained using a 3-dimensional fast-spoiled gradient-echo sequence with the following factors: oblique-axial orientation (plane passing through the anterior-posterior commissures); 1-mm isotropic field of view, 256 × 192 × 210 mm; repetition time, 7.9 milliseconds; echo time, 3.0 milliseconds; inversion time, 450 milliseconds; and flip angle, 20°.
Jensen S.K., Dickie E.W., Schwartz D.H., Evans C.J., Dumontheil I., Paus T, & Barker E.D. (2015). Effect of Early Adversity and Childhood Internalizing Symptoms on Brain Structure in Young Men. JAMA pediatrics, 169(10), 938-946.
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6

Longitudinal Brain MRI and MRS in Infant

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Brain MRI and MRS were initially performed at 2 years and 6 months of life on a 3T magnet (General Electric, Milwaukee, WI). The following pulse sequences of the brain were acquired: sagittal spoiled gradient echo (SPGR) T1WI, axial T2WI, axial T2 FLAIR, axial susceptibility weighted angiography (SWAN), coronal fat-saturated T2WI, and axial diffusion tensor imaging (DTI) with seven non-collinear directions of encoding. Single voxel MRS was performed with a 2 × 2 × 2 cm voxel over the left cerebral deep gray nuclei (TR 1500; TE 35 and 288 msec).
A follow-up brain MRI was performed at age 3 years and 2 months (3T MRI; General Electric) with similar sequences. Axial arterial spin-labeling (ASL) perfusion images and coronal high resolution T2WI through the hippocampi were also acquired. Single voxel MRS was performed with a 2 × 2 × 2 cm voxel over the left cerebral deep gray nuclei (TR 1500; TE 144 msec) and left parietal white matter (TR 1500; TE 35 and 144 msec).
Ferreira C.R., Whitehead M.T, & Leon E. (2017). Biotin-thiamine responsive basal ganglia disease: Identification of a pyruvate peak on brain spectroscopy, novel mutation in SLC19A3, and calculation of prevalence based on allele frequencies from aggregated next-generation sequencing data. American journal of medical genetics. Part A, 173(6), 1502-1513.
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7

Preoperative Brain MRI Assessment

Cited 1 time
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MR imaging was performed preoperatively on a 3T magnet (General Electric, Milwaukee, WI). Sequences obtained included conventional T1- and T2-weighted imaging, diffusion-tensor imaging (DTI), and gradient-echo (GRE) sequences, as well as MR spectroscopy of the basal ganglia. Our neuroradiologist (JM) reviewed postnatal, pre-operative brain MRI and scored MRIs according to the Magnetic Resonance Imaging Abnormality Scoring System used by Andropoulos et al.33 (link) This scoring system categorizes brain MRI abnormalities as (i) white matter injury (WMI) , (ii) infarction (INF), (iii) intraparenchymal hemorrhage (IPH), (iv) punctate lesions (PL), (v) lactate peak on MRS (lactate), (vi) intraventricular hemorrhage (IVH), (vii) subdural hemorrhage (SDH), or (viii) deep venous sinus thrombosis (DVST). Abnormalities in each category are given a score of 0-3 (0=none, 1=mild, 2=moderate, 3=severe) and weighted by a significance multiplier.33 (link) For WMI, INF, and IPH the significance multiplier is 3, for PL and lactate the significance multiplier is 2, and for IVH, SDH, and DVST the significance multiplier is 1. Scores used in the analysis are derived from summated scores of all categories after application of the significance multiplier.
Schlatterer S.D., Govindan R.B., Murnick J., Barnett S.D., Lopez C., Donofrio M.T., Mulkey S.B., Limperopoulos C, & du Plessis A.J. (2021). In Infants with Congenital Heart Disease Autonomic Dysfunction is Associated with Pre-Operative Brain Injury. Pediatric research, 91(7), 1723-1729.
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8

Multiparametric MRI for Prostate Cancer Evaluation

Cited 1 time
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All the scans were performed with a 3 T magnet (GE Healthcare, Waukesha, WI) using an endorectal coil and 8-channel abdominal array. Gadopentetate dimeglumine (Berlex Laboratories, Wayne, NJ) was injected into a peripheral vein (0.15 mmol/kg; rate 3ml/sec) followed by a 20 ml saline flush. Spoiled gradient echo (SPGR) T1-weighted sequences with repetition time (TR) 385 ms, echo time (TE) 6.2 ms and α 65°. T2-weighted (T2W) sequences were acquired using fast spin echo, repetition time (TR) 3500 ms and echo time (TE) 102 ms. The field of view (FOV) was >16 cm2 and the in-phase dimension was < 0.7 × 0.4 mm (phase × frequency). DWI sequences were performed on a free breathing spin echo and spectral fat saturation with TR 2500 ms, TE 65 ms for b value 0,500 and TR 3000 ms, TE 80 ms for b value 0,1400 s/mm2. In addition, 3D SPGR DCE sequences were performed using 3D gradient echo with TR 3.6 ms, TE 1.3 ms, α ° 15 FOV = 26×26 cm2 including the entire prostate gland and seminal vesicles, with temporal resolution of 5 s, and total observation time of 5 minutes, as described previously [22 (link)]. Subtracted DCE images were generated. MRI was obtained more than 50 days after biopsy to minimize post-biopsy changes.
Taghipour M., Ziaei A., Alessandrino F., Hassanzadeh E., Harisinghani M., Vangel M., Tempany C.M, & Fennessy F.M. (2019). Investigating the role of DCE-MRI, over T2 and DWI, in accurate PI-RADS v2 assessment of clinically significant peripheral zone prostate lesions as defined at radical prostatectomy. Abdominal radiology (New York), 44(4), 1520-1527.
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