Crizotinib was obtained from ShangHai Biochempartner (ShangHai, China); alectinib, cabozantinib, and ceritinib (LDK378) were purchased from ActiveBiochem (Hong Kong), 17-AAG was purchased from LC Laboratories (Woburn, MA, USA); NVP-TAE-684 and ASP3026 were purchased from ChemieTek (Indianapolis, IN, USA); AP26113 was purchased from Selleck (Cambridge, MA); and Foretinib was purchased from AdooQ BioScience (Irvine, CA, USA). Each compound was dissolved in dimethyl sulfoxide (DMSO) for cell culture experiments. For inhibitor screening, the SCADS Inhibitor kit was provided by the Screening Committee of Anticancer Drugs supported by a Grant-in-Aid for Scientific Research on Innovative Areas, Scientific Support Programs for Cancer Research, from the Ministry of Education, Culture, Sports, Science, and Technology of Japan.
Asp3026
Manufactured by Chemietek
Sourced in United States
The ASP3026 is a laboratory equipment designed for sample preparation. It is a compact and automated liquid handling system that can perform various liquid handling tasks such as pipetting, diluting, and mixing samples with high precision and accuracy. The core function of the ASP3026 is to automate and streamline sample preparation processes in a laboratory setting.
Automatically generated - may contain errors
Lab products found in correlation
Alectinib, by Active Motif (2 mentions)
Nvp tae 684, by Chemietek (2 mentions)
Ap26113, by Selleck Chemicals (2 mentions)
17 aag, by LC Laboratories (2 mentions)
Ceritinib, by Active Motif (1 mentions)
Cabozantinib, by Active Motif (1 mentions)
Foretinib, by Adooq (1 mentions)
Cabozantinib, by Selleck Chemicals (1 mentions)
Foretinib, by Selleck Chemicals (1 mentions)
Ponatinib, by Selleck Chemicals (1 mentions)
Nintedanib, by Selleck Chemicals (1 mentions)
3 protocols using asp3026
1
Inhibitor Screening for Cancer Research
2
High-throughput Screening of Kinase Inhibitors
Check if the same lab product or an alternative is used in the 5 most similar protocols
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High-throughput inhibitor screening was performed using the SCADS Inhibitor kit-1, 3 or 4, provided by the Screening Committee of Anticancer Drugs supported by a Grant-in-Aid for Scientific Research on Innovative Areas, Scientific Support Programs for Cancer Research, from the Ministry of Education, Culture, Sports, Science and Technology of Japan. ASP3026 (ChemieTek), TAE684, AEW541 (ActiveBiochem), AP26113-analog (Biochempartner), cabozantinib, foretinib, ponatinib (Selleck), afatinib (BIBW2992, ChemieTek), E7080 (Selleck), motesanib (ChemieTek), CEP701 (Calbiochem) and nintedanib (Selleck) were appended to the library (for a total of 282 compounds). Wild-type CD74-ROS1, F2004V- and F2075C-mutated cells were seeded in triplicate in 96-well plates, and each inhibitor was added at 10, 100 nM, 1, or 3 μM. A DMSO-treated well used in each plate as a control. After 72 h of exposure to the inhibitors, cell viability was measured by the CellTiter-Glo assay.
3
Compound Sourcing for Cell Experiments
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