DIM (99.1% purity) was obtained from Fagron (São Paulo, Brazil). Span® 80 (sorbitan monooleate), 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), 3(4,5-dimethyl)-2,5diphenyltetrazolium bromide (MTT), Dulbecco’s Modified Eagle’s Medium (DMEM), penicillin/streptomycin, 0.25% trypsin/EDTA solution, and fetal bovine serum (FBS) were obtained from Sigma-Aldrich Co. (San Luis, MO, USA). Pomegranate oil was supplied by Florien (Piracicaba, SP, Brazil). Ethylcellulose was donated by Colorcon (Cotia, Brazil). Pullulan was donated by Hayashibara (Okayama, Japan). Polyethylene glycol (PEG 400) was acquired from Labimpex (São Paulo, SP, Brazil). Glycerol was obtained from Nova Química do Sul (Porto Alegre, RS, Brazil). Gellan gum low acyl (Kelcogel®) was donated by CP Kelco (Atlanta, GA, USA). Karaya gum was presented by Metachem (São Paulo, SP, Brazil). All other chemicals and solvents were analytical grade and used as received.
Ethyl cellulose
Manufactured by Colorcon
Sourced in Brazil, United States, China
Ethyl cellulose is a type of lab equipment used in various applications. It is a water-insoluble, thermoplastic, cellulose-based polymer that can be used as a film-forming agent, binder, and sustained-release matrix.
Automatically generated - may contain errors
Lab products found in correlation
Span 80, by Merck Group (1 mentions)
Penicillin streptomycin, by Merck Group (1 mentions)
Dulbecco s modified eagle s medium dmem, by Merck Group (1 mentions)
Fetal bovine serum (fbs), by Merck Group (1 mentions)
Hydroxypropyl methylcellulose, by Thermo Fisher Scientific (1 mentions)
Dialysis tubing cellulose membrane, by Merck Group (1 mentions)
Hydroxypropyl cellulose, by Thermo Fisher Scientific (1 mentions)
Magnesium stearate, by Colorcon (1 mentions)
4 protocols using ethyl cellulose
1
Pomegranate Oil-Loaded Microemulsion Development
2
Cyanocobalamin Buccal Delivery Formulation
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Cyanocobalamin was donated by Planet Pharma, Eudragit (S100, L100, and L100-55) by Evonik Industries, and Mannitol by Pharmacare PLC. Hydroxy propyl cellulose (M.W. 100,000) and hydroxy propyl methyl cellulose ((2% aq. Soln., 20 °C) 7500–14,000 mPa.s) were purchased from Alfa Aesar (Haverhill, MA, USA); ethyl cellulose, microcrystalline cellulose PH 101, polyplasedone, and magnesium stearate from Colorcon® (Milan, Italy); sublingual bovine mucosa from a local butcher (Palestine); PermeaPad® membrane from innoME GmbH (Espelkamp, Germany); dialysis tubing cellulose membrane and polyvinyl pyrrolidine (MW 40,000) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Xanthan gum, carbopol, sodium hydroxide pellets, sodium chloride, disodium hydrogen phosphate, potassium dihydrogen phosphate, potassium chloride, absolute anhydrous ethanol 100%, acetonitrile, and hydrochloric acid 37% were obtained from Birzeit University laboratories (Ramallah, Palestine).
3
Potassium Chloride Sustained-Release Formulation
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Potassium chloride was supplied from the Mekophar (Viet Nam); ethyl cellulose was kindly offered from Colorcon (Viet Nam). Carnauba wax (KahlWax, Germany) and stearyl alcohol (India) were purchased. All materials complied with the specification of pharmacopoeia or analytical grade. Kaleorid® LP (batch No. DA 8417, Leo Pharmaceutical Products, Denmark) was used as reference product to compare dissolution profiles and absorption in bioequivalence study.
4
Purification and Characterization of Acetylharpagide
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Acetylharpagide was purified through macroporous resin columns after water extraction. The method is described in the Chinese patents, numbered as 200510085017.2 and 201110022703.0. The purity of acetylharpagide was more than 98% by HPLC. Standards of acetylharpagide and cinnamic acid were obtained from National Institutes for Food and Drug Control. Microcrystalline cellulose (MCC, MW ≈ 30,000), sodium carboxymethyl starch (CMS-Na, MW ≈ 5 × 105~1 × 106), hydroxypropyl methylcellulose (HPMC, MW ≈ 86,000), polyethylene glycol 6000 (PEG-6000, MW ≈ 6,000), and magnesium stearate were pharmaceutical grade and obtained from Beijing Fenglijingqiu Commerce and Trade Co. Ltd. Talcum powder, polyacrylic resin II (dissolved at pH ≥ 6.0, MW ≈ 1.5 × 105), and polyacrylic resin III (dissolved at pH ≥ 7.0, MW ≈ 1.5 × 105) were pharmaceutical grade and obtained from Huzhou Zhanwang Pharmaceutical Co. Ltd. Ethyl cellulose (EC,MW ≈ 20,000) was pharmaceutical grade and obtained from Colorcon (China). Diethyl phthalate (DEP) and triethyl citrate (TEC) were analysis grade and procured from A Johnson Matthey Company. All other chemicals and solvents were of the chromatographic and pharmaceutical grade.
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