Quark

Manufactured by Cosmed

Sourced in Italy, United States

Quark is a versatile lab equipment product designed for a range of applications. It is a compact, high-performance device that can be used for various analytical tasks. Quark's core function is to provide accurate and reliable data measurements, making it a valuable tool for researchers and scientists in various fields.

Automatically generated - may contain errors

Lab products found in correlation

Excalibur sport, by Lode Ergometry (1 mentions) Omnia software, by Cosmed (1 mentions) Corival, by Lode Ergometry (1 mentions) Fibroscan 502 touch, by Echosens (1 mentions) Lunar prodigy, by GE Healthcare (1 mentions) Corescan software, by GE Healthcare (1 mentions) Vantage nv, by Polar Electro (1 mentions) Quark cpet gas analyzer, by Cosmed (1 mentions) Excalibur, by Lode Ergometry (1 mentions)

Close spelling variants of this product

Quark b2 (65 citations) Quark RMR (54 citations) Quark PFT Ergo (19 citations) Quark CPET system (13 citations) Quark T12 (10 citations) Quark CPET metabolic cart (7 citations) Quark Cardiopulmonary Exercise Testing (3 citations) Quark PFT 2 spirometer (3 citations) Quark PFT Ergo device (3 citations) Quark CPET Gas Analyzer (2 citations)

28 protocols using quark

Maximal Oxygen Uptake and Aerobic Power

Check if the same lab product or an alternative is used in the 5 most similar protocols

In the week preceding the study (∼7 days), V˙O2max and MAP were assessed via an incremental cycle test performed on an electronically braked cycle ergometer (Excalibur Sport, Lode, Groningen, Netherlands) as previously described (Impey et al., 2015 (link)). Briefly, following a 10‐min warm‐up at 100 W, workload was increased in 30 W increments ever 2 min until volitional failure. Breath‐by‐breath oxygen uptake (V˙O2) and carbon dioxide uptake (V˙CO2) were obtained throughout the exercise using an online gas analysis system (Quark, Cosmed, Rome, Italy). End‐point criteria for V˙O2max being achieved were: (1) heart rate within 10 beats min⁻¹ of age‐predicted maximum, (2) respiratory exchange ratio >1.1, and (3) plateau of oxygen consumption despite increased workload. MAP was calculated as per Hawley & Noakes (1992 (link)).

Bennett S., Brocherie F., Phelan M.M., Tiollier E., Guibert E., Morales‐Artacho A.J., Lalire P., Morton J.P., Louis J.B, & Owens D.J. (2023). Acute heat stress amplifies exercise‐induced metabolomic perturbations and reveals variation in circulating amino acids in endurance‐trained males. Experimental Physiology, 108(6), 838-851.

+ Open protocol

+ Expand

Graded Treadmill Test for Aerobic Capacity

Check if the same lab product or an alternative is used in the 5 most similar protocols

A peak exertion, clinician-supervised graded treadmill stress test was performed with indirect calorimetry (Quark, Cosmed USA, Chicago, IL), as previously described,^{14 (link)} to assess cardiac function and aerobic capacity (VO₂peak). Tests were terminated at the subject’s request or when criteria set forth by American College of Sports Medicine were met.¹⁵ Subjects were allowed handrail support, but were instructed to minimize handrail use to that necessary to maintain balance. VO₂peak was defined as the highest oxygen consumption value obtained in the last minute of exercise. Peak aerobic testing was determine preintervention and repeated after 24 weeks of intervention (postintervention).

Serra M.C., Accardi C.J., Ma C., Park Y., Tran V., Jones D.P., Hafer-Macko C.E, & Ryan A.S. (2019). Metabolomics of Aerobic Exercise in Chronic Stroke Survivors: A Pilot Study. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association, 28(12), 104453.

+ Open protocol

+ Expand

Postprandial energy metabolism in PKU

Check if the same lab product or an alternative is used in the 5 most similar protocols

At fasting status, rate of oxygen (V ̇O2) consumption and carbon dioxide production (V ̇CO2) were measured using indirect calorimetry (Quark, COSMED, Italy). Participants then were provided with a PKU-type breakfast (e.g. low-protein bread, jam and low-protein cookies) containing 395 kcals for children and 490 kcals for adults. The Control group received a similar breakfast based on normal foods with calorific content and weight matched to that of the PKU group. Postprandial measurements of VO2 and VCO2 were performed for a period of 90 minutes. Fasting and postprandial respiratory exchange ratio (RER), FOx, CHOOx and RMR were calculated using the Frayn equations( 5) and DIT as percentage increment in energy expenditure above RMR.

Alghamdi N., Alfheeaid H., Cochrane B., Adam S., Galloway P., Cozens A., Preston T., Malkova D, & Gerasimidis K. (2021). Mechanisms of obesity in children and adults with phenylketonuria on contemporary treatment. Clinical nutrition ESPEN, 46.

+ Open protocol

+ Expand

Resting Energy Expenditure Assessment

Cited 1 time

Check if the same lab product or an alternative is used in the 5 most similar protocols

Indirect calorimetry was performed using an open canopy system (Quark, Cosmed, Rome, Italy). Subjects were placed under the canopy while resting in bed in a thermally neutral environment. This was combined with resting heart rate (HR) recording using an integrated fingertip pulse meter (ipod, Nonin Medical Inc., Plymouth, MN). Subjects were told to close their eyes and try to sleep, refrain from fidgeting, and not to perform any type of activity (i.e., watching TV or reading). The duration of the test was between 30 min to assure a minimal steady state of 20 min with the first 10 min of data discarded. Oxygen consumption (V̇O₂) and carbon dioxide production (V̇CO₂) were recorded every 10 s (Omnia software, Cosmed) and used for the computation of respiratory exchange ratio (RER=V̇CO₂/V̇O₂) also known as respiratory quotient at rest. Resting energy expenditure (EE) was calculated using Weir's equation: REE = [(3.9 × V̇O2) + (1.1 × V̇CO2)] [19 (link)]. Systemic rate of fat oxidation (Fat-ox) and carbohydrate oxidation (CHO-ox) were computed as previously described [20 (link)]. Protein oxidation rates were not measured based on the assumption that the amount of protein oxidized are quantitatively negligible compared to glucose and fatty acid oxidation [21 (link)].

Tankeu A.T., Van Winckel G., Campos-Xavier B., Braissant O., Pedro R., Superti-Furga A., Amati F, & Tran C. (2021). Classical homocystinuria, is it safe to exercise?. Molecular Genetics and Metabolism Reports, 27, 100746.

+ Open protocol

+ Expand

Comprehensive Cardiorespiratory and Body Composition Assessment

Check if the same lab product or an alternative is used in the 5 most similar protocols

Cardiorespiratory fitness was assessed by measuring oxygen consumption during maximum exercise effort on a treadmill (ACSM, 2014). Work rate was increased by speed and grade until the subject reached voluntary exhaustion, maximum aerobic capacity, or safety criteria defined by the American College of Sports Medicine (ACSM, 2014). VO₂peak was measured by indirect calorimetry (Quark, Cosmed USA, Chicago, IL) and defined as the highest oxygen consumption value obtained in the last 30‐sec increment.
Subjects had fat mass, lean tissue mass, and bone mineral content determined by dual‐energy X‐ray absorptiometry (DXA) (Prodigy, LUNAR Radiation Corp., Madison, WI). Fat‐free mass (FFM) was defined as the sum of lean tissue mass and bone mass. Mid‐thigh muscle cross‐sectional area and subcutaneous fat area were determined from a single mid‐thigh computed tomography (CT) slice; abdominal visceral fat (VAT) and subcutaneous abdominal fat were determined at a single abdominal slice at the lumbar spine L4‐L5 level (Medical Imaging Processing Analysis and Visualization software (MIPAV), version 7.0.0). Muscle attenuation (intramuscular fat) by CT was measured in Hounsfield units (Ryan and Harduarsingh‐Permaul 2014).

Ortmeyer H.K., Ryan A.S., Hafer‐Macko C, & Oursler K.K. (2016). Skeletal muscle cellular metabolism in older HIV‐infected men. Physiological Reports, 4(9), e12794.

+ Open protocol

+ Expand

Measurement of Peak Oxygen Consumption

Cited 1 time

Check if the same lab product or an alternative is used in the 5 most similar protocols

Peak oxygen consumption (VO_2peak) was measured by indirect calorimetry (Quark, Cosmed USA, Chicago, IL) during a graded treadmill exercise test on a motorized treadmill. Subjects walked at a constant velocity with the grade initially set to 0% and increasing 4% after the first 2 minutes and 2% every 2 min thereafter to volitional exhaustion, as reported previously (Ivey et al., 2007 (link); Prior et al., 2009 (link)). Tests were terminated at the subject’s request or according to criteria set forth by American College of Sports Medicine (Pescatello et al., 2014 ). Subjects were allowed handrail support but were instructed to minimize handrail use to that necessary to maintain balance. VO_2peak was defined as the highest oxygen consumption value obtained in the last minute of exercise.

Landers-Ramos R.Q., Serra M.C., Blumenthal J.B., Ryan A.S., Hafer-Macko C.E, & Prior S.J. (2018). Type 2 diabetes and older age contribute to elevated plasma microparticle concentrations independent of chronic stroke. Experimental physiology, 103(11), 1560-1570.

+ Open protocol

+ Expand

Screening Protocol for T2D Subjects

Cited 2 times

Check if the same lab product or an alternative is used in the 5 most similar protocols

This manuscript builds on data from two different studies, both including subjects with T2D (25 (link)). Exclusion criteria were pregnancy, smoking, contraindication to increased levels of physical activity (26 (link)), insulin dependence, and evidence of thyroid, liver, lung, heart, or kidney disease. All subjects underwent a screening consisting of a medical interview and examination, an oral glucose tolerance test (OGTT), a walking VO₂peak test with indirect calorimetry (Cosmed K4B2, Rome, Italy) and a familiarization VO₂max test performed on a treadmill (Katana Sport, Lode, Groningen, the Netherlands) with indirect calorimetry (Cosmed Quark, Rome, Italy) as previously described (22 (link), 27 (link)). Written and informed consent was obtained from all research participants before any investigations were performed and the studies were approved by the Ethical Committee of the Capital Region of Denmark (H-6-2014-043 and H-1-2013-116) and registered at www.ClinicalTrials.gov (NCT02320526) and (NCT02089477).

Karstoft K., Brinkløv C.F., Thorsen I.K., Nielsen J.S, & Ried-Larsen M. (2017). Resting Metabolic Rate Does Not Change in Response to Different Types of Training in Subjects with Type 2 Diabetes. Frontiers in Endocrinology, 8, 132.

+ Open protocol

+ Expand

Cardiorespiratory Fitness Assessment via VO2max

Check if the same lab product or an alternative is used in the 5 most similar protocols

Cardiorespiratory fitness was determined by assessing

\overset{\cdot}{V}

O_2max during a graded treadmill test with indirect calorimetry (Quark, Cosmed USA). Exercise tests were conducted utilizing a protocol we have used numerous times previously in older athletes, and included standard ECG monitoring (Rogers et al., 1990 (link); Brooks et al., 1996 ). The exercise test continued until maximal effort or exhaustion was achieved. For exercise tests to be considered maximal, participants had to reach both a plateau in

\overset{\cdot}{V}

O_2max with increasing workload and a respiratory exchange ratio >1.1. The highest

\overset{\cdot}{V}

O₂ attained during the test was recorded as

\overset{\cdot}{V}

O_2max. The maximal exercise test was conducted several hours after the baseline MRI scan.

Alfini A.J., Weiss L.R., Leitner B.P., Smith T.J., Hagberg J.M, & Smith J.C. (2016). Hippocampal and Cerebral Blood Flow after Exercise Cessation in Master Athletes. Frontiers in Aging Neuroscience, 8, 184.

+ Open protocol

+ Expand

Measuring Maximal Oxygen Uptake

Cited 1 time

Check if the same lab product or an alternative is used in the 5 most similar protocols

V̇O_2max was measured by indirect calorimetry (Quark, Cosmed USA, Chicago, Ill., USA) during a constant-speed treadmill protocol with 2% increases in incline every 2 min until exhaustion as previously described (Prior et al. 2014 (link)). V̇O_2max was defined as the highest oxygen consumption (V̇O₂) value obtained for a 30-s increment. V̇O₂ was considered maximum if the following standard criteria were met: respiratory exchange ratio > 1.10 or a plateau in V̇O₂ with an increase in workload.

Landers-Ramos R.Q., Corrigan K.J., Guth L.M., Altom C.N., Spangenburg E.E., Prior S.J, & Hagberg J.M. (2016). Short-term exercise training improves flow-mediated dilation and circulating angiogenic cell number in older sedentary adults. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 41(8), 832-841.

+ Open protocol

+ Expand

Maximal Cardiopulmonary Exercise Test

Check if the same lab product or an alternative is used in the 5 most similar protocols

On the third testing day, participants performed a maximal cardiopulmonary exercise test (CPET) to assess gas exchange parameters (Quark; Cosmed, Rome, Italy) and advise training intensities (Heine et al., 2014; van den Akker et al., 2015) . For the CPET, an electrically braked cycle ergometer (Lode Corival) was used, with a ramp-protocol at 25 W + 10 W/min in women, and 25 W + 15 W/min in men. The following outcomes were included: peak workload (W), peak oxygen uptake (VO 2 peak), and peak heart rate (expressed as the percentage of the age-predicted maximal heart rate). In addition, three supplemental outcomes were selected to represent the tri-axel cardiopulmonary system (Wasserman et al., 2011) , namely the peak O 2 pulse, the min ventilation/carbon dioxide slope, and the VO 2 /work rate slope.

Heine M., Richards R., Geurtz B., Los F., Rietberg M., Harlaar J., Gerrits K., Beckerman H, & de Groot V. (2019). Preliminary effectiveness of a sequential exercise intervention on gait function in ambulant patients with multiple sclerosis - A pilot study. Clinical biomechanics (Bristol, Avon), 62.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!