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Aquilion 4

Manufactured by Toshiba
Sourced in Japan

The Aquilion 4 is a multi-slice computed tomography (CT) scanner developed by Toshiba. It is capable of acquiring four simultaneous slices of image data during a single rotation of the X-ray tube.

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4 protocols using aquilion 4

1

Multimodal Imaging for Oncologic Assessment

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All 17 patients had undergone unenhanced and contrast-enhanced CT scans, and 6 patients had also undergone FDG-PET/CT imaging. CT imaging was performed using Multi-Slice CT (Aquilion 16 and Aquilion 4, Toshiba, Yokohama, Japan), with a tube potential of 135 kV, a current of 350 mA, field of view of 250 mm × 250 mm, and reconstruction slice thickness of 2 mm and 7 mm. The contrast agent iohexol was used at a concentration of 300 mg I/mL. The dose used was 1.5 mL/kg, with an injection flow rate of 1.5 mL/s to 2.5 mL/s. CT scans were obtained 60 s after administering the contrast agent.
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2

Chest CT Imaging for Lung Cancer Tumor Measurement

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In general, patients underwent chest CT within 1 month before surgery. Chest CT was performed with the patient in the supine position during inspiratory breath-hold using various multidetector row scanners: Aquilion 4 (TOSHIBA Corporation, Tokyo, Japan), Aquilion 64 (TOSHIBA), Aquilion ONE (TOSHIBA), Aquilion ONE Vision (TOSHIBA), SOMA-TOM Plus4 Volume Zoom (SIEMENS, Munich, Germany), Brilliance CT (Philips, Amsterdam, The Netherlands), and Brilliance iCT (Philips). The imaging parameters for thin-section CT were as follows: tube voltage, tube current; 100 to 500 mA; 120 kVp; scan field of view, 320 to 360 mm; and slice thickness, 2 mm. A real exposure control (TOSHIBA) or automatic exposure control (SIEMENS and Philips) was added to each study. All of the CT data sets were transferred to a picture archiving and communication system, which was accessible by the workstations (Volume Analyzer; SYNAPSE VINCENT, Fujifilm Corp, Tokyo, Japan) with a specialized application for the lungs. The greatest diameter of consolidation in each tumor (C) and the greatest diameter of the whole tumor including GGO (T) were adopted with axial 2-dimensional CT
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3

Chest CT Scanning for Lung Imaging

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Chest CT scanning was performed in a supine position during inspiratory breath‐hold using various multi‐detector row scanners: Aquilion 4 (Toshiba), Aquilion 64 (Toshiba), Aquilion ONE (Toshiba), Aquilion ONE Vision (Toshiba), SOMATOM Plus4 Volume Zoom (Siemens), Briliance CT (Phillips), and Briliance iCT (Phillips). Imaging parameters for thin‐section CT were as follows: tube voltage 120 kVp; tube current 100–500 mA; scan field of view 320–360 mm; and slice thickness 2 mm. A real exposure control (Toshiba) of automatic exposure control (Siemens and Phillips) was added in each study. All CT data sets were transferred to a Picture Archiving and Communication System, which was accessible for workstations (Volume Analyzer, Synapse‐Vincent, Fujifilm, Tokyo) with a specialized application for the lungs.
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4

CT Imaging Analysis of Tumor Consolidation

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All patients underwent CT imaging in the supine position during inspiratory breath‐hold using various multidetector row scanners (Aquilion 4, Aquilion 64, Aquilion ONE, Aquilion ONE Vision [Toshiba], SOMATOM Plus4 Volume Zoom [Siemens Medical Solutions, Malvern], Brilliance CT, and Brilliance iCT [Philips Healthcare]).
The diameter of consolidation in each tumor and the diameter of the whole tumor, including GGO, were measured with axial two‐dimensional CT data at 2‐mm slice thicknesses, and the CTR was calculated. The CT images were evaluated by three of the authors (Y.O., K.T., and T.K.). When independent assessments disagreed, the images were viewed and discussed together to reach a final consensus. Patients were assigned to four groups of CTR = 0; 0 < CTR < 0.5; 0.5 ≤ CTR < 1; and CTR = 1. Additionally, tumors without GGO component were defined as the pure‐solid group (CTR = 1) and the other tumors with GGO were defined as the GGO group (0 ≤ CTR < 1).
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