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Ppg1000

Manufactured by Merck Group
Sourced in United States

The PPG1000 is a laboratory equipment manufactured by Merck Group. It is designed to perform precise measurement and analysis of various samples. The core function of the PPG1000 is to measure the physical properties of materials, such as particle size, zeta potential, and molecular weight. The device utilizes advanced optical techniques to provide accurate and reliable data for research and development purposes.

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4 protocols using ppg1000

1

Foam Stability of Polymer Solutions

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Example 12

Solutions of concentration 1000 ppm w/v of poly(propylene glycol) with Mn 1000 (PPG1000, Sigma Aldrich, St. Louis, Mo.), poly(2-ethyl-2-oxazoline) with Mn 5000 and PDI≤1.2 (POX5000, Sigma Aldrich, St. Louis, Mo.), Methocel E3LV (Dow Chemical Company, Midland, Mich.), polysorbate 80 (PS80, Sigma Aldrich, St. Louis, Mo.), and Pluronic F68 (F68, BASF Corporation) were prepared using ultrapure deionized water (18.2 MΩ·cm at 25° C.). 3 mL of each solution was placed into a 5-mL polypropylene tube and vortexed on a Mini Vortex Mixer (VWR, Radnor, Pa.) on mixer setting #8 for 15 seconds. The foam heights were measured after vortexing and are listed in Table 20. The times for the foams to dissipate were also recorded and are listed in Table 20. The foams for the POX5000 and F68 samples did not dissipate over the course of the experiment. The stopping points are listed in Table 20.

TABLE 20
ExcipientFoam height (in)Foam dissipation time (s)
PPG10000.254
POX50000.6327
Methocel E3LV1.00>1125
PS800.257
F681.25>1125

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2

Foam Stability of Polymer Solutions

Check if the same lab product or an alternative is used in the 5 most similar protocols

Example 12

Solutions of concentration 1000 ppm w/v of poly(propylene glycol) with Mn 1000 (PPG1000, Sigma Aldrich, St. Louis, Mo.), poly(2-ethyl-2-oxazoline) with Mn 5000 and PDI≤1.2 (POX5000, Sigma Aldrich, St. Louis, Mo.), Methocel E3LV (Dow Chemical Company, Midland, Mich.), polysorbate 80 (PS80, Sigma Aldrich, St. Louis, Mo.), and Pluronic F68 (F68, BASF Corporation) were prepared using ultrapure deionized water (18.2 MΩ·cm at 25° C.). 3 mL of each solution was placed into a 5-mL polypropylene tube and vortexed on a Mini Vortex Mixer (VWR, Radnor, Pa.) on mixer setting #8 for 15 seconds. The foam heights were measured after vortexing and are listed in Table 20. The times for the foams to dissipate were also recorded and are listed in Table 20. The foams for the POX5000 and F68 samples did not dissipate over the course of the experiment. The stopping points are listed in Table 20.

TABLE 20
ExcipientFoam height (in)Foam dissipation time (s)
PPG10000.254
POX50000.6327
Methocel E3LV1.00>1125
PS800.257
F681.25>1125

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3

Preparation of Structured Tribo-Fluids

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Poly(propylene glycol)s PPG400 and PPG1000 (CAS 25322-69-4, Sigma-Aldrich, St. Louis, MO, USA) were used as a liquid phase and Aerosil®200 (CAS 112 945-52-5, Evonik Industries, Hanau-Wolfgang, Germany) hydrophilic-fumed silica as a solid phase for STF preparation, respectively. Table 1 shows the properties of the materials used for STF preparation.
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4

Foam Characterization of Polymeric Excipients

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Example 12

Solutions of concentration 1000 ppm w/v of poly(propylene glycol) with Mn 1000 (PPG1000, Sigma Aldrich, St. Louis, Mo.), poly(2-ethyl-2-oxazoline) with Mn 5000 and PDI ≤1.2 (POX5000, Sigma Aldrich, St. Louis, Mo.), Methocel E3LV (Dow Chemical Company, Midland, Mich.), polysorbate 80 (PS80, Sigma Aldrich, St. Louis, Mo.), and Pluronic F68 (F68, BASF Corporation) were prepared using ultrapure deionized water (18.2 MΩ·cm at 25° C.). 3 mL of each solution was placed into a 5-mL polypropylene tube and vortexed on a Mini Vortex Mixer (VWR, Radnor, Pa.) on mixer setting #8 for 15 seconds. The foam heights were measured after vortexing and are listed in Table 20. The times for the foams to dissipate were also recorded and are listed in Table 20. The foams for the POX5000 and F68 samples did not dissipate over the course of the experiment. The stopping points are listed in Table 20.

TABLE 20
ExcipientFoam height (in)Foam dissipation time (s)
PPG10000.254
POX50000.6327
Methocel E3LV1.00>1125
PS800.257
F681.25>1125

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