Ticlopidine

Manufactured by Fujifilm

Sourced in Japan

Ticlopidine is a laboratory reagent used in various analytical and research applications. It is a chemical compound that serves as an antiplatelet agent, inhibiting the activation and aggregation of platelets. Ticlopidine is utilized in research and testing protocols where the evaluation of platelet function or the assessment of antiplatelet properties is required.

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Lab products found in correlation

3 protocols using ticlopidine

Chemical Compound Acquisition for Research

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Erythromycin, clarithromycin, roxithromycin, diltiazem, ritonavir, ketoconazole, fluconazole, cimetidine, ticlopidine, omeprazole, fluvoxamine, paroxetine, fluoxetine, quinidine, aflatoxin B1, and sterigmatocystin were obtained from Wako, Japan. Gestodene and mifepristone were obtained from Tokyo Chemical Industry, Japan. G418 was obtained from Funakoshi, Japan. Ethinylestradiol, rifampicin, tienilic acid, terbinafine, hypoxanthine, aminopterin, and thymidine (HAT) and 4,6-diamidino-2-phenylindole (DAPI) were obtained from Sigma Aldrich, USA. All other chemicals were of the highest grade commercially available.

Satoh D., Iwado S., Abe S., Kazuki K., Wakuri S., Oshimura M, & Kazuki Y. (2017). Establishment of a novel hepatocyte model that expresses four cytochrome P450 genes stably via mammalian-derived artificial chromosome for pharmacokinetics and toxicity studies. PLoS ONE, 12(10), e0187072.

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Antiplatelet Drugs: Synthesis and Characterization

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Clopidogrel was purchased from LKT Laboratories (St. Paul, MN). Ticlopidine and olive oil were purchased from Wako (Osaka, Japan). Ticagrelor was purchased from Sequoia Research Products Ltd (Oxford, UK). All other chemicals used were commercially available and of reagent grade.

Yamamoto H., Takada T., Yamanashi Y., Ogura M., Masuo Y., Harada-Shiba M, & Suzuki H. (2017). VLDL/LDL acts as a drug carrier and regulates the transport and metabolism of drugs in the body. Scientific Reports, 7, 633.

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Pharmacological Reagent Procurement Protocol

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Test drugs were purchased from Combi-Blocks (San Diego, CA, USA), FLUKA (Charlotte, NC, USA), Kyowa Medex (Tokyo, Japan), LKT Laboratories (St. Paul, MN, USA), MedChemExpress (Princeton, NJ, USA), MP Biomedicals (Santa Ana, CA, USA), Selleck Chemicals (Houston, TX, USA), Sigma-Aldrich (St. Louis, MO, USA), Tokyo Chemical Industry (Tokyo, Japan), Toronto Research Chemicals (North York, ON, Canada) or FUJIFILM Wako Pure Chemical (Osaka, Japan). Quinidine was purchased from Tokyo Chemical Industry. Sulfaphenazole, α-naphthoflavone, and flutamide were purchased from Sigma-Aldrich. Ketoconazole was purchased from LKT Laboratories. Ticlopidine was purchased from FUJIFILM Wako Pure Chemical. β-Nicotinamide-adenine dinucleotide phosphate (NADP+), D-glucose-6-phosphate, and glucose 6-phosphate dehydrogenase were purchased from Oriental Yeast (Tokyo, Japan).

Shimizu Y., Sasaki T., Yonekawa E., Yamazaki H., Ogura R., Watanabe M., Hosaka T., Shizu R., Takeshita J.I, & Yoshinari K. (2021). Association of CYP1A1 and CYP1B1 inhibition in in vitro assays with drug-induced liver injury. The Journal of toxicological sciences, 46(4).

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