Opadry ca

Manufactured by Colorcon

Sourced in United Kingdom

Opadry® CA is a water-soluble, film-forming polymer used for the coating of solid oral dosage forms. It is designed to provide a protective, functional, and aesthetic coating for tablets, capsules, and other oral solid dosage forms.

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Lab products found in correlation

Potassium dihydrogen phosphate, by Merck Group (2 mentions) Hydrochloric acid (hcl), by Merck Group (2 mentions) Sodium chloride (nacl), by Merck Group (2 mentions) Sodium hydroxide (naoh), by Merck Group (2 mentions) Avicel ph 101, by Merck Group (1 mentions) Acetonitrile, by Merck Group (1 mentions) Acetone, by Merck Group (1 mentions) Magnesium stearate, by Merck Group (1 mentions) Aerosil, by Merck Group (1 mentions)

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Opadry (7 citations)

2 protocols using opadry ca

Formulation and Characterization of Metoclopramide Hydrochloride Tablets

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Metoclopramide Hydrochloride was gifted from GSK. (336.3 g/mol, 98.0%-101% w/w, Batch number IMGAB), with the expiry of 03–2024. Colorcon Limited (Kent, UK) provided Opadry^® CA. Avicel pH 101 (226 g/mol, 97% w/w), Magnesium stearate (591.257 g/mol, ≥99.5% w/w) and Aerosil (60.08 g/mol, 99.8% w/w), were purchased from Sigma-Aldrich, Germany. Sodium chloride (58.44 g/mol, ≥99.5% w/w), Sodium hydroxide (40.00 g/mol, ≥99% w/w), Potassium Dihydrogen phosphate (136.08 g/mol, ≥99.5% w/w), Acetone (58.08 g/mol, ≥99.8% w/w) Acetonitrile (41.05 g/mol ≥99.9), and Hydrochloric acid (36.458 g/mol, 37–38% w/w) were obtained from Merck, Germany.

Farooqi S., Yousuf R.I., Shoaib M.H., Ahmed K., Ansar S, & Husain T. (2020). Quality by Design (QbD)-Based Numerical and Graphical Optimization Technique for the Development of Osmotic Pump Controlled-Release Metoclopramide HCl Tablets. Drug Design, Development and Therapy, 14, 5217-5234.

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Tramadol HCl Sustained Release Formulation

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Tramadol HCl (% purity = >99.8%) was gifted from Atco Pharmaceuticals (Karachi, Pakistan). Opadry^® CA (fully formulated osmotic coating system composed of cellulose acetate as water insoluble component and polyethylene glycol (PEG) as pore-former) and Methocel™ K4M Premium grade were provided by Colorcon Limited (Kent, United Kingdom). Avicel™ PH-101, Magnesium Stearate, and Aerosil™ 200 were purchased from FMC Corporation (United States). Sodium Chloride [≥99.5% w/w], Potassium dihydrogen Phosphate [≥99.5% w/w], sodium hydroxide [≥99% w/w] and hydrochloric acid [37–38% w/w] were purchased from Merck (Germany).

Saleem M.T., Shoaib M.H., Yousuf R.I., Ahmed F.R., Ahmed K., Siddiqui F., Mahmood Z.A., Sikandar M, & Imtiaz M.S. (2022). SeDeM tool-driven full factorial design for osmotic drug delivery of tramadol HCl: Formulation development, physicochemical evaluation, and in-silico PBPK modeling for predictive pharmacokinetic evaluation using GastroPlus™. Frontiers in Pharmacology, 13, 974715.

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