Anti lyn clone lyn 01

Manufactured by BioLegend

Anti-Lyn (clone LYN-01) is a monoclonal antibody that recognizes the Lyn protein. Lyn is a member of the Src family of tyrosine kinases and is involved in the regulation of various cellular processes. The antibody can be used for the detection and analysis of Lyn expression in biological samples.

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Lab products found in correlation

Phospho erk t202 y204, by Cell Signaling Technology (2 mentions) Anti syk clone 5f5, by BioLegend (2 mentions) Anti ly6g clone rc6 8c5, by R&D Systems (2 mentions) Cd11b, by BD (1 mentions) Cd11a, by BD (1 mentions) Hrp conjugated secondary antibody, by Santa Cruz Biotechnology (1 mentions)

Close spelling variants of this product

Mouse monoclonal anti-Lyn (clone LYN-01, (2 citations)

2 protocols using anti lyn clone lyn 01

Multiparameter Phosphoprotein Analysis

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Abs directed against phosphotyrosine (PY1000), phospho–spleen tyrosine kinase (Syk) (Y525/526), phospho-pan Src (Y527 and Y416), phospho-Akt (S473), phospho-p38 (T180, Y182), and phospho-Erk (T202, Y204) were from Cell Signaling Technology. Anti-Syk (clone 5F5) and anti-Lyn (clone LYN-01) were from BioLegend. Anti-Ly6G (clone RC6-8C5) was obtained from R&D Systems. Anti-BSA and anti-lactoferrin Abs were from Sigma and an Ab against β-COP was a gift from Nick Ktistakis (The Babraham Institute, Cambridge, U.K.). HRP-conjugated secondary Abs were from Santa Cruz Biotechnology and Bio-Rad. Fluorescently conjugated Abs for flow cytometry were obtained from eBioscience (F4/80, GR1), BioLegend (CD11b, CD11a, CD16/32, Ly6G, CD62L, CD19), and BD (Ly6C).

Vermeren S., Miles K., Chu J.Y., Salter D., Zamoyska R, & Gray M. (2016). PTPN22 Is a Critical Regulator of Fcγ Receptor–Mediated Neutrophil Activation. The Journal of Immunology Author Choice, 197(12), 4771-4779.

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Antibodies for Signaling Pathway Analysis

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Antibodies directed against phosphotyrosine (PY1000), phospho-Syk (Y525/526), phospho-pan Src (Y527 and Y416), phospho-Akt (S473), phospho-p38 (T180, Y182) and phospho-Erk (T202, Y204) were from Cell Signaling Technology. Anti-Syk (clone 5F5) and anti-Lyn (clone LYN-01) were from Biolegend. Anti-Ly6G (clone RC6-8C5) was obtained from R&D Systems. Anti-BSA and anti-lactoferrin antibodies were from Sigma and an antibody against β-COP was a gift from Nick Ktistakis (The Babraham Institute, Cambridge). HRP-conjugated secondary antibodies were from Santa Cruz Biotechnology and Biorad. Fluorescently-conjugated antibodies for flow cytometry were obtained from eBioscience (F4/80, GR1), Biolegend (CD11b, CD11a, CD16/32, Ly6G, CD62L, CD19) and BD (Ly6C).

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