Trio tim whole body mri scanner

MRI was performed on a 3-Tesla Trio TIM whole-body MRI scanner (Siemens), equipped with a 12-channel phased-array head coil. DTI was performed using a pair of pulsed-gradient, spin-echo sequences with a single-shot echo-planar imaging readout. A parallel imaging algorithm (generalized autocalibrating partial-parallel acquisition) was applied during diffusion imaging to reduce echo-planar distortion. DTI parameters were 8400-ms time to repetition, 91-ms time to echo, 180° flip angle, 2×2 mm pixel size, 128×128 resolution (256 ×256 mm field of view), 64 2-mm thick slices with no gap, and 9 min 56 s total imaging time. Diffusion-sensitizing gradient encoding was applied in 68 uniform angular directions with a diffusion weighting of b = 1000 s/mm². A reference image with no diffusion gradient (b = 0) was also acquired.

All imaging was performed on a 3T Trio TIM whole-body MRI scanner (Siemens, Erlangen, Germany). RS-fMRI data were acquired using a gradient-echo echo-planar imaging sequence (TR= 2 s, TE= 24 ms, flip angle= 90°, voxel size= 3.44x3.44x4.00 mm³, 36 axial slices). Each participant completed one seven-minute RS-fMRI run (i.e., 210 volumes). During the RS-fMRI run, participants were instructed to keep their eyes open. An eye-tracker outsider the scanner was used to monitor participants’ eyes, to ensure that they did not fall asleep during the scan. After the functional scans, high-resolution anatomic images were obtained using a T1-weighted 3D MPRAGE sequence (TR= 12.24 ms, TE= 3.56 ms, flip angle= 23°, voxel size= 0.98×0.98×1 mm³, 192 sagittal slices).