Phosphate buffer saline (pbs)

The peptides KK-11 and KKd-11 were purchased from China Peptides Co., Ltd. The peptides had a purity of 97% which was verified by high-performance liquid chromatography (HPLC) and mass spectrum (MS). The peptide powder was store at −20°C before use. Phosphate Buffer Saline (PBS), hydrochloric acid (HCl), sodium hydroxide (NaOH), and medium were purchased from Sinopharm Chemical Reagent (China). All aqueous solutions were prepared with deionized (DI) water from Milli-Q-Water (Millipore Corp, 18.2 MΩ/cm at 25°C).

Polycaprolactone (PCL, mean M_w = 8 × 10⁴ g/mol) and Polyvinyl pyrrolidone (PVP, mean M_w = 1.3 × 10⁶ g/mol) were purchased from Sigma-Aldrich Ltd., St Louis, USA. Tetracycline hydrochloride (TE-HCL) was purchased from Amresco, USA. Acetic acid and Phosphate buffer saline (PBS, PH = 7.4) were obtained from Sinopharm Chemical Reagent Co., Ltd, Shanghai, China. All materials were used as received without further purification treatment. All purchased materials were of the analytical grade.

Cetyltrimethylammonium chloride (CTAC), tetraethyl orthosilicate, 2,7-dichlorofluorescein diacetate (DCFH-DA), dopamine hydrochloride, Hoechst 33258, and ethanol butanol were purchased from Aladdin Biochemical Technology Co., Ltd. (Shanghai, China). Dimethyl thiazole blue (MTT) was purchased from Beijing Solarbio Corporation (Beijing, China). DSF, fluorescein isothiocyanate (FITC), and indocyanine green (ICG) were purchased from Macklin Biochemical Co., Ltd. (Shanghai, China). Cupric nitrate trihydrate (Cu(NO₃)₂·3H₂O), ammonia solution (NH₃·H₂O), hydrochloric acid (HCl), dimethyl sulfoxide, hydrogen peroxide (H₂O₂), triethanolamine, and phosphate buffer saline (PBS) were purchased from Sinopharm Chemical Reagent Co., Ltd. (Shanghai, China). The L929 and HCT116 cells were supplied by the Cell Bank of the Chinese Academy of Sciences (Shanghai, China). Acridine orange/ethidium bromide reagent was purchased from Yuan Ye Biological Co., Ltd. (Shanghai, China). Deionized water was used in this study, and all the compounds utilized in the experiments were of analytical grade, including the aforementioned compounds.
All experiments involving animals were approved by the Animal Ethics Committee of Zhejiang Ocean University (approval No. 2021055). Male BALB/c nude mice (18–22 g) were provided by the Ziyuan Laboratory Animals (Hangzhou, China).

Interphotoreceptor retinoid-binding protein (IRBP) peptide (amino acids 1177–1191; sequence, ADG SSW EGV GVV PDV) and primers were synthesized by Shanghai Sangon Biological Engineering Technology & Services Co., Ltd. (Shanghai, China). Complete Freund's Adjuvant (CFA) and 2-mercaptoethanol were purchased from Sigma-Aldrich (St. Louis, MO, USA). Mycobacterium tuberculosis (TB, strain H37RA) was purchased from Difco (Difco Laboratories, Detroit, MI, USA). Recombinant rat IL-2, fluorescein isothiocyanate- (FITC-) conjugated TLR4 antibody, and phycoerythrin- (PE-) conjugated IL-10 antibody were purchased from Peprotech (Rocky Hill, NJ, USA), Thermo Fisher Scientific (Waltham, MA, USA), and BD Pharmingen (Mountain View, CA, USA), respectively. Phosphate buffer saline (PBS, pH 7.4, 20 mmol/L), formaldehyde, paraffin, hematoxylin, and eosin (HE) were purchased from Sinopharm Chemical Reagent Co., Ltd. (Shanghai, China). RPMI 1640 medium was purchased from Gibco; Thermo Fisher Scientific, Ltd. (Waltham, MA, USA). IL-10 (JYM0651Ra) ELISA kit was purchased from Dakewe Biotech Co., Ltd. (Beijing, China). Toll-like receptor 4 (JYM0085Ra) ELISA kit was purchased from Wuhan ColorfulGene biological technology Co., Ltd. (Wuhan, China).

CA white powder (acetyl group = 39.8 wt.%), PEG (M_w = 2000), and PVP K13–18 (M_w = 10,000) were purchased from Aladdin Reagent Co., Ltd. (Shanghai, China). PVP K30 (M_w = 50,000) was supplied by Sigma-Aldrich Trading Co., Ltd. (Shanghai, China). Cur, acetone, ethanol, N, N-dimethylformamide (DMF), Tween 80, and phosphate buffer saline (PBS) were purchased from Sinopharm Chemical Reagent Co., Ltd. (Shanghai, China). Methylene blue and magenta powders used for dyeing working fluids were purchased from Tianjin Zhiyuan Chemical Reagent Co., Ltd. (Tianjin, China). All chemical reagents were used directly without further purification.