Cilostazol (USP grade) was gifted from BioChem (Seoul, Korea). Vinylpyrrolidone-vinyl acetate copolymer (Kollidon® VA64), polyvinyl caprolactam–polyvinyl acetate–polyethylene glycol graft copolymer (Soluplus®), d -α-Tocopheryl polyethylene glycol 1000 succinate (TPGS®), and Polyethoxylated castor oil (Cremophor®) were kindly donated by BASF (Ludwigshafen, Germany); and microcrystalline cellulose (Avicel®) was provided by FMC Korea (Seoul, Korea). High-performance liquid chromatography (HPLC)-grade methanol (MeOH) and acetonitrile (ACN) were purchased from Burdick & Jackson (Muskegon, MI, USA). All other chemicals and solvents used were of analytical grade or above. The Gastroplus™ software for PBPK simulation was purchased from SimulationsPlus (San Diego, CA, USA), and the basic database and physiological data provided by Gastroplus™ was used for drug simulation. Pletaal® tablets were purchased from Otsuka Pharmaceutical (Tokyo, Japan).
Cremophor
Manufactured by BASF
Sourced in Germany
Cremophor is a non-ionic solubilizing agent and emulsifier primarily used in the formulation of pharmaceutical and cosmetic products. It serves as a carrier and dispersing agent to enhance the solubility and bioavailability of active ingredients.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using cremophor
1
Cilostazol Formulation Development and Evaluation
2
Nanocarrier Formulations for Drug Delivery
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Granular l -α-lecithin was supplied by Acros (Thermo Fisher Scientific, Waltham, MA, USA). Pluronic series F87, F127, and F68, TPGS, and Cremophor (ELP and RH40) were purchased from BASF (Hanover, Germany). Que and Pluronic series L121, F108, and P123 were purchased from Sigma-Aldrich Co. (St Louis, MO, USA). DSPE-PEG2K was from NOF (Tokyo, Japan). Heparin 5,000 IU/mL was provided by China Chemical & Pharmaceutical (Hsinchu, Taiwan). Dulbecco’s Modified Eagle’s Medium, fetal bovine serum, and glutamine were purchased from Biowest (Nuaillé, France). All reagents for the high-performance liquid chromatographic (HPLC) analysis were of HPLC grade, and other reagents were of analytical grade.
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