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Pox5000

Manufactured by Merck Group

The POX5000 is a versatile laboratory equipment designed for a wide range of scientific applications. Its core function is to provide accurate and reliable measurements of various parameters, ensuring consistent and reproducible results. The device is built with high-quality components and undergoes rigorous testing to ensure its performance and durability.

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3 protocols using pox5000

1

Foam Stability of Polymer Solutions

Check if the same lab product or an alternative is used in the 5 most similar protocols

Example 12

Solutions of concentration 1000 ppm w/v of poly(propylene glycol) with Mn 1000 (PPG1000, Sigma Aldrich, St. Louis, Mo.), poly(2-ethyl-2-oxazoline) with Mn 5000 and PDI≤1.2 (POX5000, Sigma Aldrich, St. Louis, Mo.), Methocel E3LV (Dow Chemical Company, Midland, Mich.), polysorbate 80 (PS80, Sigma Aldrich, St. Louis, Mo.), and Pluronic F68 (F68, BASF Corporation) were prepared using ultrapure deionized water (18.2 MΩ·cm at 25° C.). 3 mL of each solution was placed into a 5-mL polypropylene tube and vortexed on a Mini Vortex Mixer (VWR, Radnor, Pa.) on mixer setting #8 for 15 seconds. The foam heights were measured after vortexing and are listed in Table 20. The times for the foams to dissipate were also recorded and are listed in Table 20. The foams for the POX5000 and F68 samples did not dissipate over the course of the experiment. The stopping points are listed in Table 20.

TABLE 20
ExcipientFoam height (in)Foam dissipation time (s)
PPG10000.254
POX50000.6327
Methocel E3LV1.00>1125
PS800.257
F681.25>1125

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2

Foam Stability of Polymer Solutions

Check if the same lab product or an alternative is used in the 5 most similar protocols

Example 12

Solutions of concentration 1000 ppm w/v of poly(propylene glycol) with Mn 1000 (PPG1000, Sigma Aldrich, St. Louis, Mo.), poly(2-ethyl-2-oxazoline) with Mn 5000 and PDI≤1.2 (POX5000, Sigma Aldrich, St. Louis, Mo.), Methocel E3LV (Dow Chemical Company, Midland, Mich.), polysorbate 80 (PS80, Sigma Aldrich, St. Louis, Mo.), and Pluronic F68 (F68, BASF Corporation) were prepared using ultrapure deionized water (18.2 MΩ·cm at 25° C.). 3 mL of each solution was placed into a 5-mL polypropylene tube and vortexed on a Mini Vortex Mixer (VWR, Radnor, Pa.) on mixer setting #8 for 15 seconds. The foam heights were measured after vortexing and are listed in Table 20. The times for the foams to dissipate were also recorded and are listed in Table 20. The foams for the POX5000 and F68 samples did not dissipate over the course of the experiment. The stopping points are listed in Table 20.

TABLE 20
ExcipientFoam height (in)Foam dissipation time (s)
PPG10000.254
POX50000.6327
Methocel E3LV1.00>1125
PS800.257
F681.25>1125

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3

Foam Characterization of Polymeric Excipients

Check if the same lab product or an alternative is used in the 5 most similar protocols

Example 12

Solutions of concentration 1000 ppm w/v of poly(propylene glycol) with Mn 1000 (PPG1000, Sigma Aldrich, St. Louis, Mo.), poly(2-ethyl-2-oxazoline) with Mn 5000 and PDI ≤1.2 (POX5000, Sigma Aldrich, St. Louis, Mo.), Methocel E3LV (Dow Chemical Company, Midland, Mich.), polysorbate 80 (PS80, Sigma Aldrich, St. Louis, Mo.), and Pluronic F68 (F68, BASF Corporation) were prepared using ultrapure deionized water (18.2 MΩ·cm at 25° C.). 3 mL of each solution was placed into a 5-mL polypropylene tube and vortexed on a Mini Vortex Mixer (VWR, Radnor, Pa.) on mixer setting #8 for 15 seconds. The foam heights were measured after vortexing and are listed in Table 20. The times for the foams to dissipate were also recorded and are listed in Table 20. The foams for the POX5000 and F68 samples did not dissipate over the course of the experiment. The stopping points are listed in Table 20.

TABLE 20
ExcipientFoam height (in)Foam dissipation time (s)
PPG10000.254
POX50000.6327
Methocel E3LV1.00>1125
PS800.257
F681.25>1125

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