Saccharin sodium saccharin

Manufactured by Thermo Fisher Scientific

Sourced in United States

Saccharin (sodium saccharin) is a commonly used artificial sweetener in laboratory settings. It is a white, crystalline powder that provides a sweet taste without contributing calories or carbohydrates to a formulation.

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Lab products found in correlation

Fluoxetine hydrochloride, by Spectrum Chemical (1 mentions)

Close spelling variants of this product

Saccharin sodium Saccharin

2 protocols using saccharin sodium saccharin

Racemic Methylone and Fluoxetine Effects

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Racemic methylone and fluoxetine used in the present study were dissolved in isotonic saline (0.9%) and both were injected intraperitoneally (IP) at 10 mg/kg. Methylone was generously synthesized and provided by the drug design and synthesis section (MTMDB, NIDA, and NIAAA) and fluoxetine hydrochloride was synthesized by Spectrum Chemical MFG. Corp. All drug and vehicle solutions were prepared daily and subsequently passed through a 0.2 um filter, prior to injection, to remove any potential particulates. Saccharin (sodium saccharin, Acros Organics, NJ, USA) was prepared as a 1 g/L (0.1%) solution in tap water.

Manke H.N., Rice K.C, & Riley A.L. (2023). Effects of Methylone Pre-Exposure on Fluoxetine-Induced Conditioned Taste Avoidance in Male and Female Sprague-Dawley Rats. Brain Sciences, 13(4), 585.

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Pharmacological Evaluation of MDPV, Methylone, and MDMA

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Racemic MDPV hydrochloride and methylone hydrochloride (synthesized and provided by the Drug Design and Synthesis section, MTMDB, NIDA and NIAAA) were dissolved in isotonic saline (0.9%) and injected intraperitoneally (IP) at 1.8 mg/kg and 10 mg/kg, respectively. Racemic MDMA hydrochloride (synthesized and provided by the Drug Design and Synthesis section, MTMDB, NIDA and NIAAA) was dissolved in isotonic saline (0.9%) and injected subcutaneously (SC) at 1.0 mg/kg. Drug and vehicle solutions were prepared daily and passed through a 0.2-um filter prior to injection to remove any potential particulates. Saccharin (sodium saccharin, Acros Organics) was prepared as a 1 g/L (0.1%) solution in tap water.

Manke H.N., Nelson K.H., Huang S., Bailey J.M., Bowman S.K., Jones R.A., Cerveny S.E., Rice K.C, & Riley A.L. (2022). Methylone Pre-exposure Differentially Impacts the Aversive Effects of MDPV and MDMA in Male and Female Sprague-Dawley Rats: Implications for Abuse Vulnerability. Pharmacology, biochemistry, and behavior, 220, 173470.

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