Szn 6 trinocular stereo zoom macroscope

Manufactured by Optika

Sourced in Italy

The SZN-6 trinocular stereo zoom macroscope is a laboratory instrument equipped with a trinocular viewing system and a zoom function. It provides a magnification range from 0.7x to 4.5x. The macroscope features high-quality optics and a sturdy construction.

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Lab products found in correlation

Kimtech precision wipes, by Kimberly-Clark (1 mentions) Vision lite 2, by Optika (1 mentions)

2 protocols using szn 6 trinocular stereo zoom macroscope

In Vitro Evaluation of Implant Characteristics

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Implants were treated as for the in vitro drug release studies described above. At pre-determined time points:

(i)

Pictures of the implants were taken with a SZN-6 trinocular stereo zoom macroscope (Optika), equipped with an optical camera (Optika Vision Lite 2.1 software). The lengths and diameters of the implants were determined using the software ImageJ (US National Institutes of Health). Dynamic changes in the systems' volume were calculated considering cylindrical geometry.

(ii)

Implant samples were withdrawn and excess water was carefully removed using Kimtech precision wipes (Kimberly-Clark, Rouen, France) and weighed [wet mass (t)]. The change in wet mass (%) (t) was calculated as follows:

change in wet mass (%) (t) = \frac{wet mass (t) - mass (t = 0)}{mass (t = 0)} \times 100 %

where mass (t = 0) denotes the implant mass before exposure to the release medium.
All experiments were conducted in triplicate. Mean values +/− standard deviations are reported.

Bassand C., Benabed L., Freitag J., Verin J., Siepmann F, & Siepmann J. (2022). How bulk fluid renewal can affect in vitro drug release from PLGA implants: Importance of the experimental set-up. International Journal of Pharmaceutics: X, 4, 100131.

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Implant Measurement and Imaging

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Pictures of implants before exposure to the release medium were taken using a SZN-6 trinocular stereo zoom macroscope (Optika, Ponteranica, Italy), equipped with an optical camera (Optika Vision Lite 2.1 software). The lengths and diameters of the implants were determined using the software ImageJ (US National Institutes of Health, Bethesda, Maryland, USA).

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