Median score and 5–95 percentile were plotted. Skp2 expression among different groups according to pathological grading, lymph node metastasis, smoking status and differentiation grade were evaluated by Kruskal-Wallis H-test which is a non-parametric method for testing whether samples originate from the same distribution. Wilcoxon matched-pairs signed rank test were used to compare Skp2 expression in LUAD and LUSC Pearson's χ2 was used to compare Skp2 expression in other clinical features, including histological, age, sex, tumor size and distant metastasis. Disease-free survival (DFS) was defined as the period between surgery and the date of recurrence, and overall survival (OS) was considered as the interval from surgery to the date of mortality or final follow-up. Kaplan-Meier method with the log-rank test was performed to determine the difference in survival between groups. Cox proportional hazards regression analysis was performed to estimate the hazard ratios for positive risk factors with the backward conditional elimination method (24 (link)). P<0.05 was considered to indicate a statistically significant difference (two sided). SPSS 22.0 statistic software (IBM Corp., Armonk, NY, USA) and GraphPad Prism 6 software (GraphPad Software, Inc., La Jolla, CA, USA) were used to perform the computation for all statistical analyses.
Spss 22.0 statistic software
Manufactured by IBM
Sourced in United States
SPSS 22.0 is a statistical software package developed by IBM. It provides advanced analytical capabilities to users, allowing them to analyze and interpret data. The software offers a range of statistical techniques, including regression analysis, hypothesis testing, and data exploration. SPSS 22.0 is designed to assist researchers, analysts, and decision-makers in various industries and fields of study.
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Lab products found in correlation
2 protocols using spss 22.0 statistic software
1
Skp2 Expression and Survival Analysis in NSCLC
2
Prognostic Role of MCM4 in HCC
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To investigate the correlation between MCM4 protein expression status and clinical pathological characteristics of HCC patients, we divided HCC patients into two groups according to the expression of MCM4 protein.
The associations between MCM4 protein expression subcutaneously injected into the left flank of 8week-old BALB/c nude mice (Slac Laboratory Animal Co. Ltd, Shanghai, China). The mice were euthanized 4 weeks postinjection, and the tumors were excised and fixed for subsequent histopathological examination and analysis. Meanwhile, tumor volumes were measured twice a week after two weeks, tumor volume = 1/2 (length × width 2 ). All animal experiments were approved by the Animal Care and Use Committee of Tianjin Medical University Cancer Institute & Hospital. 2.10. Statistical analyses SPSS.22.0 statistic software (IBM Corp.) was applied to analyze the data. All data are presented as the mean ± SD. Student's t-test was used for continuous variables, χ 2 tests were applied to analyze categorical variables. Survival of patients was plotted using Kaplan-Meier method. P-value was two-sided and p < 0.05 was considered to indicate a statistically significant difference.
The associations between MCM4 protein expression subcutaneously injected into the left flank of 8week-old BALB/c nude mice (Slac Laboratory Animal Co. Ltd, Shanghai, China). The mice were euthanized 4 weeks postinjection, and the tumors were excised and fixed for subsequent histopathological examination and analysis. Meanwhile, tumor volumes were measured twice a week after two weeks, tumor volume = 1/2 (length × width 2 ). All animal experiments were approved by the Animal Care and Use Committee of Tianjin Medical University Cancer Institute & Hospital. 2.10. Statistical analyses SPSS.22.0 statistic software (IBM Corp.) was applied to analyze the data. All data are presented as the mean ± SD. Student's t-test was used for continuous variables, χ 2 tests were applied to analyze categorical variables. Survival of patients was plotted using Kaplan-Meier method. P-value was two-sided and p < 0.05 was considered to indicate a statistically significant difference.
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