3 methyladenine

Manufactured by Fujifilm

Sourced in Japan

3-Methyladenine is a chemical compound used in laboratory research. It functions as an inhibitor of the DNA repair enzyme 3-methyladenine DNA glycosylase.

Automatically generated - may contain errors

Lab products found in correlation

Doxorubicin, by Merck Group (1 mentions) N acetyl l cysteine, by Fujifilm (1 mentions) Propidium iodide, by Nacalai Tesque (1 mentions) Calcein am, by Nacalai Tesque (1 mentions) Autophagy cytotoxicity dual staining kit, by Funakoshi (1 mentions)

2 protocols using 3 methyladenine

Apoptosis Induction Reagents

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Rap and Benzyloxycarbonyl-Val-Ala-Asp (OMe) fluoromethylketone (Z-VAD-FMK) were purchased from Medical and Biological Laboratories (MBL, Nagoya, Japan). N-acetyl-L-cysteine and 3-methyladenine were purchased from Wako Pure Chemical Industries (Osaka, Japan). Doxorubicin was purchased from Sigma.

Ono K., Sato T., Iyama S., Tatekoshi A., Hashimoto A., Kamihara Y., Horiguchi H., Kikuchi S., Kawano Y., Takada K., Hayashi T., Miyanishi K., Sato Y., Takimoto R., Kobune M, & Kato J. (2014). A novel strategy inducing autophagic cell death in Burkitt's lymphoma cells with anti-CD19-targeted liposomal rapamycin. Blood Cancer Journal, 4(2), e180-.

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Multiparametric Cell Viability Assay

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Propidium iodide (PI) and calcein AM (3',6'-Di(Oacetyl) -4',5'-bis[N,N-bis(carboxymethyl)aminomethyl] fluorescein tetra-acetoxymethyl ester, solution) were purchased from Nacalai Tesque (Kyoto, Japan). Nicardipine hydrochloride was obtained from a commercially available source (Sawai Pharmaceutical Co., Ltd., Osaka, Japan). The Autophagy/Cytotoxicity Dual Staining Kit was obtained from Funakoshi Co., Ltd. (Tokyo, Japan). 3-Methyladenine was purchased from Wako Pure Chemical Industries, Ltd. (Osaka, Japan). Primary human cells and growth media were obtained from EIDIA Co., Ltd. (Tokyo, Japan). The Amplite™ Fluorometric Caspase 3/7 Assay Kit was purchased from Cosmo Bio (Tokyo, Japan). All other chemicals were purchased from commercial sources.

Ochi M., Kawai Y., Tanaka Y, & Toyoda H. (2015). Characterization of nicardipine hydrochloride-induced cell injury in human vascular endothelial cells. The Journal of toxicological sciences, 40(1).

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