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Xe991 10 10 bis 4 pyridinylmethyl 9 10h anthracenone

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Sourced in United Kingdom

XE991 (10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone) is a chemical compound that functions as a potent and selective inhibitor of the KCNQ (Kv7) family of voltage-gated potassium channels.

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2 protocols using xe991 10 10 bis 4 pyridinylmethyl 9 10h anthracenone

1

Neurochemical Reagents for Receptor Studies

Check if the same lab product or an alternative is used in the 5 most similar protocols
5-Hydroxytryptamine (serotonin, 5HT), gamma-aminobutyric acid (GABA), capsaicin, ritanserin, tropisetron hydrochloride along with bulk chemicals were obtained from Sigma-Aldrich (Vienna, Austria). Bradykinin, 6-(1,1-Dimethylethyl)-2-[(2-furanylcarbonyl) amino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid (CaCC Inh. - A01), SB 204741 (N-(1-Methyl-1H-5-indolyl)-N′ -(3-methyl-5-isothiazolyl)urea), thapsigargin, and XE991 (10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone) were purchased from Tocris (Bristol, UK). 4-(4-fluorobenzoyl)-1-(4phenylbutyl) piperidine (4 F 4 PP) oxalate was obtained from Santa Cruz Biotechnology, Inc. (Heidelberg, Germany), capsazepine from Sanova Pharma Ges. m. b. H. (Vienna, Austria), 8-[5-(2,4-dimethoxy-5-(4-trifluoromethylphenylsulphonamido) phenyl-5-oxopentyl]-1,3,8-triazaspiro[4,5]decane-2,4-dione (RS102221) from Szabo-Scandic (Vienna, Austria), and tetrodotoxin (TTX) from Latoxan (Valence, France).
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2

Neurochemical Reagents for Receptor Studies

Check if the same lab product or an alternative is used in the 5 most similar protocols
5-Hydroxytryptamine (serotonin, 5HT), gamma-aminobutyric acid (GABA), capsaicin, ritanserin, tropisetron hydrochloride along with bulk chemicals were obtained from Sigma-Aldrich (Vienna, Austria). Bradykinin, 6-(1,1-Dimethylethyl)-2-[(2-furanylcarbonyl) amino]-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic acid (CaCC Inh. - A01), SB 204741 (N-(1-Methyl-1H-5-indolyl)-N′ -(3-methyl-5-isothiazolyl)urea), thapsigargin, and XE991 (10,10-bis(4-pyridinylmethyl)-9(10H)-anthracenone) were purchased from Tocris (Bristol, UK). 4-(4-fluorobenzoyl)-1-(4phenylbutyl) piperidine (4 F 4 PP) oxalate was obtained from Santa Cruz Biotechnology, Inc. (Heidelberg, Germany), capsazepine from Sanova Pharma Ges. m. b. H. (Vienna, Austria), 8-[5-(2,4-dimethoxy-5-(4-trifluoromethylphenylsulphonamido) phenyl-5-oxopentyl]-1,3,8-triazaspiro[4,5]decane-2,4-dione (RS102221) from Szabo-Scandic (Vienna, Austria), and tetrodotoxin (TTX) from Latoxan (Valence, France).
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