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In vivo

Manufactured by Siemens

In Vivo is a versatile lab equipment product from Siemens. It is designed to facilitate in vivo studies and experiments. The core function of In Vivo is to provide a controlled environment for observing and analyzing biological processes within living organisms.

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2 protocols using in vivo

1

Multimodal MRI Evaluation of Cartilage Repair

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All MRI scans used in this study were performed during routine follow-ups.
For standard MOCART and MOCART 2.0 evaluation, a high-resolution proton-density (PD) turbo spin-echo (TSE) sequence, a T2-weighted dual fast spin-echo (Dual-FSE) sequence, and a T1-weighted turbo inversion recovery magnitude (TIRM) sequence were performed on a 3.0-T MRI unit (Tim Trio; Siemens Healthcare) in combination with a dedicated 8-channel knee coil (In Vivo). For 3D-MOCART assessment and measurement of BMELSs and subchondral overgrowth, a 3D true fast imaging with steady-state precession (True-FISP) sequence and an isotropic fat-suppressed 3D PD Sampling Perfection with Application optimized Contrasts using different flip angle Evolutions (SPACE) sequence were used (see Appendix Table A1A, available in the online version of this article).
Before 2006, a 1.0-T MRI unit (Gyroscan Intera) was used. The performed sequences—sagittal T1 spin-echo (SE) sequence, sagittal Dual-FSE sequence, and sagittal 3D gradient-echo sequence with fat suppression—are presented in Appendix Table A1B (available online).
In addition to the standard protocol, a flexible standard surface coil (TMJ coil, Gyroscan Intera; Philips) with an inner diameter of 8 cm was placed over the knee compartment of interest to scan a sagittal (femorotibial) or axial (patellofemoral) Dual-TSE sequence.
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2

Breast MRI Imaging Protocol

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Current breast MRI protocol at our institution includes prone imaging on either a GE Signa 1.5 Tesla, GE 3 Tesla HDX (General Electric Medical Systems, Milwaukee, WI), or a Siemens Trio 3 Tesla (Siemens Medical, North Carolina) scanner, using a dedicated breast surface coil (16 channel Siemens, 8 channel GE, or 7 channel InVivo (Orlando, Florida)). Sequences include a 3 plane localizing sequence, axial fat-suppressed T2W FSE or T2 STIR sequence, and axial fast spoiled gradient T1W non-fat suppressed sequence before contrast administration. Dynamic T1W fat-suppressed 3D fast spoiled gradient echo (3D FSPGR) sequences are then performed before and four times following intravenous administration of contrast (0.1 mmol/kg, Magnevist, Berlex, NJ) in the axial plane. A T1W 3D FSPGR delayed post contrast sequence is acquired in the sagittal plane. Prior to 2010, dynamic images were acquired in either the sagittal or the axial plane, with delayed imaging performed in the orthogonal plane. Post processing, including subtraction axial images, maximum intensity projections (MIP), and computer-aided diagnosis (CADSTREAM) is routinely employed.
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