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Polysorbate 80

Manufactured by Centralchem
Sourced in Slovakia

Polysorbate 80 is a non-ionic surfactant commonly used in a variety of laboratory applications. It functions as an emulsifier, dispersant, and wetting agent to promote the formation and stabilization of homogeneous solutions and dispersions.

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2 protocols using polysorbate 80

1

Topical Minoxidil Formulation Development

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All materials were of analytical grade and used as received without further purification. Alginic acid sodium salt, carrageenan and isopropyl myristate, minoxidil (MXD) were purchased from Sigma Aldrich (Steinheim, Germany). Polysorbate 80, sodium chloride, ethanol (96%) and isopropyl alcohol were purchased from Centralchem (Bratislava, Slovakia). Propylene glycol (PG) was purchased from Interpharm (Bratislava, Slovakia), Carbopol 71G NF from Lubrizol (Cleveland, USA), soybean lecithin from Dimica (ASP, Divina, Slovakia) and gelatin from Valúch (Banská Bystica, Slovakia). Double-distilled water used for the experiments was prepared at the Department of Galenic Pharmacy (Kavalier, Labo SK, Bratislava, Slovakia). Porcine ear skin was acquired from a local slaughterhouse (Stará Huta, Slovakia).
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2

Indomethacin Formulation Development

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Indomethacin (IND) was purchased from Valúch S.R.O. (Banská Bystrica, Slovakia). Macrogol 4,000, Macrogol 6,000, animal fat (Adeps solidus), Polysorbate 80, isopropyl alcohol, oleic acid, and ethanol (96%) were obtained from Centralchem S.R.O. (Bratislava, Slovakia). Isopropyl myristate was purchased from Sigma-Aldrich Chemie GmbH (Steinheim, Germany). Purified water was prepared with a distillation apparatus (Kavalier, Czech Republic).
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