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Vancomycin

Manufactured by GlaxoSmithKline

Vancomycin is a glycopeptide antibiotic used in the treatment of various bacterial infections. It is primarily used against Gram-positive bacteria, including Staphylococcus aureus and Clostridium difficile. Vancomycin functions by inhibiting cell wall synthesis in susceptible bacteria, leading to cell lysis and death.

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2 protocols using vancomycin

1

Vancomycin MIC Determination by Broth Microdilution

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The MIC of vancomycin against the isolates was determined by broth microdilution method as recommended by the CLSI (2016). Standard powders of the antibiotic (vancomycin) were obtained from GlaxoSmithKline Pharmaceutical Companies. The MIC of vancomycin against the isolates was determined using the procedure described by Wayne (2002) . Readings were taken and recorded according to the guidelines of CLSI ( 2016).
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2

Synthesis and Characterization of Titanium Nitrate Polymer Composites

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Titanium (IV) nitrate tetrahydrate (Ti(NO3)4.H2O, ≥99.9%), pure grade of polyethylene glycol (PEG), analytical-grade acetone (anhydrous, ≥99.0%), ethanol (96%), 3% of glutaraldehyde in phosphate, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), lactate dehydrogenase (LDH) rhodamine 123 dye, acridine orange/ethidium bromide (AO/EtBr) dye, dichloro dihydro fluorescein diacetate (DCFH-DA), and anhydrous sodium sulfate were acquired from Sigma-Aldrich (Hamburg, Germany). Ciprofloxacin (5 μg/disc, MASTDISCS™, Mast Diagnostics Ltd.), vancomycin (Glaxo SmithKline Pharmaceuticals Ltd.), and gentamycin (Alpha Laboratories Ltd.) were purchased from local drug stores.
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