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Araguspongin b

Manufactured by Cayman Chemical
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Sourced in United States

Araguspongin B is a chemical compound isolated from marine sponges. It has a molecular formula of C19H28O5. Araguspongin B is a naturally occurring substance that can be used for research purposes.

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Lab products found in correlation

Bapta, by Dojindo Laboratories (1 mentions) Egta am, by AAT Bioquest (1 mentions) Brefeldin a, by Nacalai Tesque (1 mentions) Ethylene glycol tetraacetic acid (egta), by Dojindo Laboratories (1 mentions) Antimycin a, by Santa Cruz Biotechnology (1 mentions) Dantrolene, by Bio-Techne (1 mentions) L leucyl l leucine methyl ester, by Cayman Chemical (1 mentions) A23187, by Bio-Techne (1 mentions) Bapta am, by Dojindo Laboratories (1 mentions) Xestospongin c, by Abcam (1 mentions) 2 apb, by Bio-Techne (1 mentions) Inositol 1 4 5 trisphosphate, by Cayman Chemical (1 mentions)

2 protocols using araguspongin b

1

Calcium Signaling Modulation Techniques

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A23187 (Tocris Bioscience), dantrolene (Tocris Bioscience), 2-APB (Tocris Bioscience), BAPTA-AM (Dojindo), BAPTA (Dojindo), EGTA (Dojindo), EGTA-AM (AAT Bioquest), 5,5′-difluoro-BAPTA-AM (PromoCell Gmbh), xestospongin C (Abcam), araguspongin B (Cayman Chemical), U73122 (Aobious, Gloucester), thapsigardin (Nacalai Tesque), brefeldin A (Nacalai Tesque), l-Leucyl-l-Leucine methyl ester (Cayman Chemical), antimycin A (Santa Cruz Biotechnology), and oligomycin (Calbiochem) were purchased.
Nozawa T., Sano S., Minowa-Nozawa A., Toh H., Nakajima S., Murase K., Aikawa C, & Nakagawa I. (2020). TBC1D9 regulates TBK1 activation through Ca2+ signaling in selective autophagy. Nature Communications, 11, 770.
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2

Targeted Silencing of SEC5 in Cell Lines

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Inositol-1,4,5-trisphosphate (Cat#10008205) and araguspongin B (Cat#10006797) were from Cayman Chemical (Ann Arbor, MI, USA). The other reagents are indicated as follows:

SiRNA-SEC5 (Shanghai GenePharma Co., Ltd., Shanghai, China)

5’-GGUCGGAAAGACAAGGCAGTT-3’

SiRNA-Negative Control (Shanghai GenePharma Co., Ltd., Shanghai, China)

5’-UUCUCCGAACGUGUC ACG UTT-3’

ShRNA-SEC5 (Shanghai Genechem Co., Ltd., Shanghai, China)
5’-CCGGGCCGAAGAGATAAAGAGATTACTCGAGTAATCTCTTTATCTCTTCGGCTTTTTT-3’
Yang L., Gu W., Cheung K.H., Yan L., Tong B.C., Jiang Y, & Yang J. (2018). InsP3R-SEC5 interaction on phagosomes modulates innate immunity to Candida albicans by promoting cytosolic Ca2+ elevation and TBK1 activity. BMC Biology, 16, 46.
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