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Farnesoid x receptor fxrβ inhibitor

Manufactured by Merck Group
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The Farnesoid X receptor (FXRβ) inhibitor is a laboratory instrument designed to measure and study the activity of the FXRβ protein, which is a member of the nuclear receptor superfamily. The FXRβ inhibitor allows researchers to investigate the role of FXRβ in various biological processes, such as bile acid homeostasis, lipid metabolism, and glucose regulation. This equipment provides a tool for researchers to better understand the function and regulation of the FXRβ receptor.

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Lab products found in correlation

Chemical grade reagents, by Merck Group (2 mentions) Mouse and human primers, by Qiagen (2 mentions) Apical sodium bile acid transporter asbt inhibitor, by Bio-Techne (2 mentions) Histamine eia kit, by Cayman Chemical (2 mentions) Real time pcr materials, by Qiagen (2 mentions)

2 protocols using farnesoid x receptor fxrβ inhibitor

1

Characterizing Liver Histamine Signaling

Cited 2 times
Check if the same lab product or an alternative is used in the 5 most similar protocols
Chemical grade reagents were purchased from Sigma-Aldrich Co (St. Louis, MO) unless stated otherwise. All mouse and human primers and real-time PCR materials were obtained from Qiagen (Fredrick, MD). Antibodies for immunohistochemistry and immunofluorescence were purchased from Abcam (Cambridge, MA) or Santa Cruz (Dallas, TX). Histamine EIA kits were purchased from Cayman Chemical (An Arbor, MI)5 (link)9 (link)10 (link). The apical sodium-bile acid transporter (ASBT) inhibitor was obtained from Tocris Bioscience (Minneapolis, MN) and the farnesoid X receptor (FXRβ) inhibitor was obtained from Sigma-Aldrich Co (St. Louis, MO). Kits to measure total bile acids (TBAs) were purchased from Crystal Chemical, Inc (Downers Grove, IL) 5 (link).
Meng F., Kennedy L., Hargrove L., Demieville J., Jones H., Madeka T., Karstens A., Chappell K., Alpini G., Sybenga A., Invernizzi P., Bernuzzi F., DeMorrow S, & Francis H. (2018). Ursodeoxycholate inhibits mast cell activation and reverses biliary injury and fibrosis in Mdr2−/− mice and human primary sclerosing cholangitis. Laboratory investigation; a journal of technical methods and pathology, 98(11), 1465-1477.
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2

Characterizing Liver Histamine Signaling

Cited 2 times
Check if the same lab product or an alternative is used in the 5 most similar protocols
Chemical grade reagents were purchased from Sigma-Aldrich Co (St. Louis, MO) unless stated otherwise. All mouse and human primers and real-time PCR materials were obtained from Qiagen (Fredrick, MD). Antibodies for immunohistochemistry and immunofluorescence were purchased from Abcam (Cambridge, MA) or Santa Cruz (Dallas, TX). Histamine EIA kits were purchased from Cayman Chemical (An Arbor, MI)5 (link)9 (link)10 (link). The apical sodium-bile acid transporter (ASBT) inhibitor was obtained from Tocris Bioscience (Minneapolis, MN) and the farnesoid X receptor (FXRβ) inhibitor was obtained from Sigma-Aldrich Co (St. Louis, MO). Kits to measure total bile acids (TBAs) were purchased from Crystal Chemical, Inc (Downers Grove, IL) 5 (link).
Meng F., Kennedy L., Hargrove L., Demieville J., Jones H., Madeka T., Karstens A., Chappell K., Alpini G., Sybenga A., Invernizzi P., Bernuzzi F., DeMorrow S, & Francis H. (2018). Ursodeoxycholate inhibits mast cell activation and reverses biliary injury and fibrosis in Mdr2−/− mice and human primary sclerosing cholangitis. Laboratory investigation; a journal of technical methods and pathology, 98(11), 1465-1477.
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