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Fos creert2

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Fos-CreERT2 is a genetically engineered fusion protein that combines the tamoxifen-inducible Cre recombinase (CreERT2) with the Fos transcription factor. It allows for the inducible and cell-type-specific expression of Cre recombinase, which can be used for conditional gene manipulation in research applications.

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Lab products found in correlation

Tcrdcreert2, by Jackson ImmunoResearch (2 mentions) Il17a, by Jackson ImmunoResearch (2 mentions) Il17rafl fl, by Jackson ImmunoResearch (2 mentions) Il17aegfp, by Genentech (2 mentions) Il23a, by Genentech (2 mentions) Syn1 cre, by Jackson ImmunoResearch (2 mentions) Cxcr6 gfp, by Jackson ImmunoResearch (2 mentions) Il1r1, by Jackson ImmunoResearch (2 mentions) C57bl 6j, by Taconic Biosciences (2 mentions) C57bl 6j, by Jackson ImmunoResearch (2 mentions) C57bl 6, by Jackson ImmunoResearch (1 mentions)

4 protocols using fos creert2

1

Genetically Engineered Mouse Models

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All experimental procedures were approved by the Hebrew University Animal Care and Use Committee. Fos-CreERT2 (ref. 25 (link)) and Ai1429 (link) were obtained from the Jackson laboratories (Background strain C57BL/6). TB mice were generated as detailed below (background strain FVB). We used the following mouse strains: Fos-CreERT2;TB double heterozygous female mice (F1 hybrid of C57BL/6 and FVB strain, 8–15 weeks old), TB heterozygous female mice (F1 hybrid of C57BL/6 and FVB strain, 9–10 weeks old), wild-type female mice (F1 hybrid of C57BL/6 and FVB strain, 9–10 weeks old) and Fos-CreERT2;Ai14 double heterozygous female mice (C57BL/6 strain, 8–10 weeks old).
Tasaka G.I., Guenthner C.J., Shalev A., Gilday O., Luo L, & Mizrahi A. (2018). Genetic tagging of active neurons in auditory cortex reveals maternal plasticity of coding ultrasonic vocalizations. Nature Communications, 9, 871.
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2

Transgenic Mouse Protocols for Neuroscience

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C57BL/6 mice were purchased from the Pengyue Laboratory of China, and transgenic mice (DAT-IRES-Cre, 006660; Ai14, 007908; Fos-CreERT2, 021,882; Vgat-IRES-Cre, 016,962) were purchased from the Jackson Laboratories. The protocols of the animal studies were approved by the Institutional Animal Care and Use Committee of Binzhou Medical University Hospital and performed in compliance with the National Institutes of Health Guide for the Care and Use of Laboratory Animals. Efforts were made to minimize animal suffering and the number of animals used.
Sun L., You J., Sun F., Cui M., Wang J., Wang W., Wang D., Liu D., Xu Z., Qiu C., Liu B, & Yan H. (2021). Reactivating a positive feedback loop VTA-BLA-NAc circuit associated with positive experience ameliorates the attenuated reward sensitivity induced by chronic stress. Neurobiology of Stress, 15, 100370.
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3

Diverse Mouse Models for Immunological Research

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All mice (C57/BL/6J, TcrdCreERT2, Ai6, CD45.1, Cxcr6GFP, Tcrd−/−, Il17a−/−, Il1r1−/−, FosCreERT2, Ai14, Il17rafl/fl, Syn1Cre) were either bred in-house or purchased from the Jackson Laboratory. The Il17aeGFP and Il23a−/− (Genentech) mice were kindly donated by Dr. Alban Gaultier and Dr. Morgan Salmon respectively. Dr. Alex Kuan kindly donated the Ccr2CreERT2: Ai6 and Ccr2RFP/RFP strains. For the microbiota experiments, germ-free (GF) and specific-pathogen free (SPF) C57/BL6/J animals were purchased from Taconic and used immediately after arrival. When purchased from JAX, animals were maintained for at least 1 week to habituate before experimentation. All experiments were approved by the Institutional Animal Care and Use Committee of the University of Virginia and adhered to ethical consideration in animal research.
de Lima K.A., Rustenhoven J., Da Mesquita S., Wall M., Salvador A.F., Smirnov I., Martelossi G.C., Mamuladze T., Baker W., Papadopoulos Z., Lopes M.B., Cao W.S., Xie X.S., Herz J, & Kipnis J. (2020). Meningeal γδ T cells regulate anxiety-like behavior via IL-17a signaling in neurons. Nature immunology, 21(11), 1421-1429.
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Diverse Mouse Models for Immunological Research

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All mice (C57/BL/6J, TcrdCreERT2, Ai6, CD45.1, Cxcr6GFP, Tcrd−/−, Il17a−/−, Il1r1−/−, FosCreERT2, Ai14, Il17rafl/fl, Syn1Cre) were either bred in-house or purchased from the Jackson Laboratory. The Il17aeGFP and Il23a−/− (Genentech) mice were kindly donated by Dr. Alban Gaultier and Dr. Morgan Salmon respectively. Dr. Alex Kuan kindly donated the Ccr2CreERT2: Ai6 and Ccr2RFP/RFP strains. For the microbiota experiments, germ-free (GF) and specific-pathogen free (SPF) C57/BL6/J animals were purchased from Taconic and used immediately after arrival. When purchased from JAX, animals were maintained for at least 1 week to habituate before experimentation. All experiments were approved by the Institutional Animal Care and Use Committee of the University of Virginia and adhered to ethical consideration in animal research.
de Lima K.A., Rustenhoven J., Da Mesquita S., Wall M., Salvador A.F., Smirnov I., Martelossi G.C., Mamuladze T., Baker W., Papadopoulos Z., Lopes M.B., Cao W.S., Xie X.S., Herz J, & Kipnis J. (2020). Meningeal γδ T cells regulate anxiety-like behavior via IL-17a signaling in neurons. Nature immunology, 21(11), 1421-1429.
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