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Dxc 600 beckman chemistry analyzer

Manufactured by Beckman Coulter
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The DxC-600 Beckman chemistry analyzer is a fully automated clinical chemistry system designed for high-volume laboratory testing. It features a modular design, allowing for flexible configuration to meet the specific needs of each laboratory. The core function of the DxC-600 is to perform a wide range of clinical chemistry tests, including routine assays and specialized panels, with high accuracy and efficiency.

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DXC 600 chemistry analyzer (2 citations) DXC-600 analyzer (2 citations) DxC-600 Beckman (1 citations)

3 protocols using dxc 600 beckman chemistry analyzer

1

Quantifying Hepatic Enzyme Levels

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To quantify the intracellular levels of GLDH and ALB, liver organoids were differentiated in PIC-LEC or Matrigel droplets for 8 days, as previously described. Organoids were provided with fresh DM 24 h before being lysed in MilliQ water. GLDH and ALB were measured in the cell lysates using a DxC-600 Beckman chemistry analyzer (Beckman Coulter). Values were normalized to total protein concentrations.
Ye S., Boeter J.W., Mihajlovic M., van Steenbeek F.G., van Wolferen M.E., Oosterhoff L.A., Marsee A., Caiazzo M., van der Laan L.J., Penning L.C., Vermonden T., Spee B, & Schneeberger K. (2020). A Chemically Defined Hydrogel for Human Liver Organoid Culture. Advanced functional materials, 30(48), 2000893.
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2

Quantification of Liver Organoid Proteins

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For the quantification of intracellular levels of GLDH and A1AT, liver organoids were differentiated for 12 days, as described. For spinner flask samples, organoids were harvested from spinner flasks at day 12 of differentiation, seeded in Matrigel droplets and cultured in DM for 24 hours. All wells were then trypsinized for cell counts. Subsequently, cells were lysed in MilliQ water. GLDH was measured in the lysates using a DxC‐600 Beckman chemistry analyzer (Beckman Coulter). A1AT was measured using an AssayMax A1AT enzyme‐linked immunosorbent assay kit (AssayPro, St. Charles, MO). Values were normalized to live cell numbers.
Schneeberger K., Sánchez‐Romero N., Ye S., van Steenbeek F.G., Oosterhoff L.A., Pla Palacin I., Chen C., van Wolferen M.E., van Tienderen G., Lieshout R., Colemonts‐Vroninks H., Schene I., Hoekstra R., Verstegen M.M., van der Laan L.J., Penning L.C., Fuchs S.A., Clevers H., De Kock J., Baptista P.M, & Spee B. (2020). Large‐Scale Production of LGR5‐Positive Bipotential Human Liver Stem Cells. Hepatology (Baltimore, Md.), 72(1), 257-270.
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3

Quantifying Hepatic Enzyme Levels

Check if the same lab product or an alternative is used in the 5 most similar protocols
To quantify the intracellular levels of GLDH and ALB, liver organoids were differentiated in PIC-LEC or Matrigel droplets for 8 days, as previously described. Organoids were provided with fresh DM 24 h before being lysed in MilliQ water. GLDH and ALB were measured in the cell lysates using a DxC-600 Beckman chemistry analyzer (Beckman Coulter). Values were normalized to total protein concentrations.
Ye S., Boeter J.W., Mihajlovic M., van Steenbeek F.G., van Wolferen M.E., Oosterhoff L.A., Marsee A., Caiazzo M., van der Laan L.J., Penning L.C., Vermonden T., Spee B, & Schneeberger K. (2020). A Chemically Defined Hydrogel for Human Liver Organoid Culture. Advanced functional materials, 30(48), 2000893.
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