MRI contrast properties were measured using a 3T MRI scanner (MAGNETOM Skyra 3T MRI, Siemens) and a low-field 0.5T NMR spectrometer (Maran Ultra 23, Resonance, Oxford, UK). Sample preparation and data analysis are described in the Supplementary Data .
Magnetom skyra 3t mri
Manufactured by Siemens
Sourced in Germany
The MAGNETOM Skyra 3T MRI is a magnetic resonance imaging (MRI) system manufactured by Siemens. It operates at a magnetic field strength of 3 tesla and is designed to provide high-quality imaging for diagnostic and research purposes.
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Lab products found in correlation
6 protocols using magnetom skyra 3t mri
1
MRI and NMR Contrast Properties
2
Measuring Inferior Vena Cava Blood Flow
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To measure the blood flow velocity of the inferior vena cava (IVC), an 18-channel body coil was used in a MAGNETOM Skyra 3T MRI (Siemens Healthcare GmbH, Erlangen, Germany), and cross-sectional 3D phase-contrast images perpendicular to the IVC blood flow direction were obtained. The image parameters were as follows: time to repeat = 5.5 msec, time to echo = 3.9 msec, flip Angle = 7°, number of excitation = 2, field of view = 285 × 380 mm, acquisition matrix = 84 × 160, slice thickness = 2.5 mm, and receiver bandwidth = 495 Hz/pixel. Velocity encoding was set in the range of 30–40 cm/s to eliminate aliasing artifacts and was applied in all directions of the x-, y-, and z-axes. During the scan, 11 to 12 frame images were acquired for every cycle, with a time resolution of 50 to 55 msec, using prospective gating that was synchronized to the peripheral pulse, and the scan time was 12 to 14 minutes depending on the patient’s cardiac cycle (Fig. 2 ). The acquired data were analyzed using prototype software (4D Flow version 2.4, Siemens Healthcare GmbH, Erlangen, Germany). A section through which blood flow passed through the IVC was selected to calculate the flow rate and 4-pixel averaged peak velocity (Fig. 3 ).
3
Multimodal Neuroimaging Protocol: T1 and DWI
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Whole-brain T1-weighted and diffusion-weighted images were acquired with a Siemens Magnetom Skyra 3 T MRI scanner (20-channel head coils) located at Aarhus University Hospital, Denmark. T1 images were acquired with the following parameters: 1.0 × 1.0 × 1.0 mm voxel size (1.0 mm3); 256 × 256 reconstructed matrix size; 2.96 ms echo time (TE); 5000 ms repetition time (TR); 240 Hz/Px bandwidth. For the reconstruction of the MEG functional data, each T1-weighted scan was co-registered to the standard brain template from the Montreal Neurological Institute (MNI) using an affine transformation. Next, it was referenced to the MEG sensors space with the data about the head shape that was previously digitalized.
Diffusion-weighted images were acquired using echo-planar imaging (EPI), with the following parameters: 2.0 × 2.0 × 2.0 mm voxel size (2.0mm3); 104 ms TE; 3300 ms TR; 100 × 100 × 72 matrix size; 221 volumes in anterior–posterior (AP) direction; 1 volume in posterior-anterior (PA) direction; 2500 s/mm2 b-value; 29.41 Hz/Px bandwidth.
Diffusion-weighted images were acquired using echo-planar imaging (EPI), with the following parameters: 2.0 × 2.0 × 2.0 mm voxel size (2.0mm3); 104 ms TE; 3300 ms TR; 100 × 100 × 72 matrix size; 221 volumes in anterior–posterior (AP) direction; 1 volume in posterior-anterior (PA) direction; 2500 s/mm2 b-value; 29.41 Hz/Px bandwidth.
4
Cerebral Hemodynamics Assessed by DSC-MRI
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One week before and 6 months after surgery, the cerebral hemodynamic status was assessed by dynamic susceptibility contrast magnetic resonance imaging (DSC‐MRI) using a MAGNETOM Skyra 3T MRI scanner (Siemens, Germany) following previously described methods (Qiao et al., 2017 (link)). The acquired DSC‐MR images were processed using a postprocessing workstation (Syngo Via 20, Siemens) and analyzed using the MR Neuro‐Perfusion software. We used the time to peak (TTP; the time at which the contrast level reached its maximum) and the mean relative cerebral blood volume (rCBV; a hemodynamic parameter calculated by MR perfusion) to evaluate the hemodynamic status of the patients.
5
High-Resolution MRI and Diffusion Imaging Protocol
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MRI data were obtained with a Siemens MAGNETOM Skyra 3 T MRI and 20-channel phased-array head/neck coil at Keelung Chang Gung Memorial Hospital in Taiwan. High-resolution anatomical images were acquired using MPRAGE T1-weighted imaging sequence in sagittal planes (TR/TE/TI = 2200/2.45/900 ms, flip angle = 8, acquisition matrix = 256 × 256, slice thickness = 1 mm, in-plane resolution = 1 mm2). Multi-shell dMRI data were acquired using the multi-band accelerated echo-planar imaging sequence (2.4-mm isotropic voxel, TR/TE = 8500/99 ms, multi-band acceleration factor = 4, phase encoding in the posterior-anterior direction, number of diffusion gradient directions = 30/64 at b = 1500/3000 s/mm2, respectively, each accompanied by one b = 0 image). An additional one b = 0 image volume was acquired with inverse phase encoding direction, specifically in the anterior-posterior direction, to correct image distortion.
6
Multimodal Brain Imaging: MEG and MRI
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MEG signals were recorded in a magnetically shielded room using a 306-channel system (204 planar gradiometers, 102 magnetometers, Elekta Neuromag TRIUX, Elekta, Stockholm, Sweden) at a sampling rate of 1 kHz. A 3D head digitizer (Fastrak, Polhemus, Colchester, Vermont, USA) was used to record the position of three cardinal points (nasion, left and right preauricular) and four head position indicator (HPI) coils (which were attached to the forehead and the mastoids) together with roughly 100-200 additional points across the participant's head. Eye movements were recorded using an eye-tracking device tracking gaze position at 1 kHz (EyeLink1000, SR Research, Ontario, Canada). On a separate day, structural MRI data were collected for each participant to reconstruct MEG activity in source space. MRI scans of each participant's brain were obtained using a Siemens Magnetom Skyra 3T MRI. The pulse sequence parameters for T1 weighted images: 1 mm isotropic resolution; field of view: 256 mm × 256 mm; 192 slices; slice thickness: 1 mm; bandwidth per pixel: 290 Hz/pixel; flip angle: 9°, inversion time (TI): 1100 ms; echo time (TE): 2.61 ms; repetition time (TR): 2300 ms. For T2 weighted images, parameters were flip angle: 11°, echo time (TE): 85.0 ms, repetition time (TR): 14,000 ms.
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