Aldh1l1 creert2 transgenic mice
Aldh1l1-CreERT2 transgenic mice express a tamoxifen-inducible Cre recombinase under the control of the aldehyde dehydrogenase 1 family, member L1 (Aldh1l1) promoter. This mouse line can be used for cell type-specific gene manipulation in astrocytes.
Lab products found in correlation
2 protocols using aldh1l1 creert2 transgenic mice
Lineage Tracing of Aldh1l1+ Cells
Astrocyte Lineage Tracing in PD Model
The copyright holder for this this version posted November 18, 2021. ; https://doi.org/10.1101/2021.11.12.468309 doi: bioRxiv preprint PTBP1 repression fails to convert reactive astrocytes to dopaminergic neurons in a PD model 4 on Laboratory Animal Care. The mice were housed in rooms with controlled 12 hours light/dark cycles, temperature, and humidity, and food and water were provided ad libitum. Eight-to ten-week-old C57BL/6 mice weighing 22-26g were obtained from the Beijing Vital River Laboratory Animal Technological Company (Beijing, China). Aldh1l1-CreER T2 transgenic mice and Rpl22 HA/HA mice (Ribotag) were obtained from The Jackson Laboratory (Stock number #029655, #011029). Hemizygous Aldh1l1-CreER T2 males or females were used for breeding to the Rpl22 HA/HA mice. Aldh1l1-CreER T2 : Ribotag mice aged at 8-10 weeks were used for lineage tracing experiments.
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