Skyra 3t mri

Manufactured by Siemens

Sourced in Germany

The Skyra 3T MRI is a magnetic resonance imaging (MRI) system produced by Siemens. It operates at a magnetic field strength of 3 Tesla, which allows for high-quality imaging. The Skyra 3T MRI is designed to acquire detailed images of the human body for diagnostic and research purposes.

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Lab products found in correlation

32 channel head coil, by Siemens (1 mentions)

Close spelling variants of this product

Skyra 3T Human MRI scanner 3T MAGNETOM Skyra whole-body MRI scanner Skyra 3T MRI unit Magnetom Skyra 3T MRI system Skyra 3T MRI system MAGNETOM Skyra 3T MRI scanner Skyra 3T MRI scanner MAGNETOM Skyra 3T MRI Skyra 3T Skyra MRI

5 protocols using skyra 3t mri

Multimodal Neuroimaging Protocol for Brain Assessments

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Participants completed a 1-h MRI acquisition on a Siemens Skyra 3 T MRI scanner (Siemens Medical Solutions, Erlangen, Germany) at the University of Miami. The 3D T1 weighted volumetric magnetization-prepared rapid gradient-echo sequence (MP-RAGE) consisted of 176 slices at slice thickness = 1 mm isotropic, FOV = 256×256, TR = 1.80s, and TE = 2.67 s. The resting-state functional MRI (rsfMRI) scan was administered for 8 min with eyes open consisting of 120 volumes and 48 interleaved slices at a slice thickness = 3.0 mm isotropic, FOV = 212×212, TR = 3.0 s, and TE = 30 ms.

Gullett J.M., DeFelice J., Richards V.L., Porges E.C., Cohen R.A., Govind V., Salan T., Wang Y., Zhou Z, & Cook R.L. (2023). Resting state connectivity in people living with HIV before and after stopping heavy drinking. Frontiers in Psychiatry, 14, 1102368.

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Diffusion Kurtosis Imaging in taVNS Treatment

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dMRI data were acquired pre- and post-taVNS treatment on a Skyra 3T MRI (Siemens Healthineers, Erlangen, Germany) immediately following feeding with swaddling to induce natural sleep. A diffusional kurtosis imaging (DKI) [23 (link)] protocol utilized b-values of b = 0, 1000 and 2000 s/mm², (3 mm)³ isotropic voxels, echo time = 122 ms, repetition time = 6700 ms with 30 diffusion-encoding directions per non-zero b-value and 40 contiguous axial slices per image volume. Additionally, 9 non-diffusion weighted (b = 0 s/mm²) images were also acquired with matching imaging parameters.
Image volumes and their corresponding diffusion-encoding directions that were corrupted by motion or signal dropout were manually removed prior to image processing. The DESIGNER pipeline [24 (link)], reformatted into Python 3 [25 ], was employed for the full DKI analysis. The pipeline includes Marchenko-Pastur-PCA denoising [26 (link)], Gibbs artifact correction [27 (link)], eddy correction [28 (link), 29 (link)], Gaussian smoothing with a kernel 1.25 times the voxel size [30 (link)] and Rician noise bias correction [31 (link)]. The output of DESIGNER is tensor-derived diffusion and kurtosis metrics; the FA was specifically focused in on for this investigation.

Aljuhani T., Haskin H., Davis S., Reiner A., Moss H., Badran B.W., George M.S., Jenkins D, & Coker-Bolt P. (2022). Transcutaneous auricular vagus nerve stimulation (taVNS) given for poor feeding in at-risk infants also improves their motor abilities. Journal of pediatric rehabilitation medicine, 15(3), 447-457.

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Multimodal MRI Acquisition Protocol

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Participants completed a 1-h MRI acquisition on a Siemens Skyra 3 T MRI scanner (Siemens Medical Solutions, Erlangen, Germany) with 32-channel head coil at Mount Sinai Medical Center, Miami Beach, Florida. The 3D T1 weighted volumetric magnetization-prepared rapid gradient-echo sequence (MP-RAGE) consisted of 176 slices at slice thickness = 1 mm isotropic, FOV = 256 × 256, TR = 3.0 s, and TE = 1.4 s. The resting-state functional MRI (rsfMRI) scan was administered with eyes open consisting of 48 interleaved slices at a slice thickness = 3.0 mm isotropic, FOV = 212 × 212, TR = 3.0 s, and TE = 30 ms. For exclusionary purposes of potential incidental findings, MRI scans were evaluated by visual inspection as well as with T2 weighted FLAIR (5 mm thick sequential axial slices), and the MP-RAGE sequence (which provides high tissue contrast and high spatial resolution with whole brain coverage).

Gullett J.M., Albizu A., Fang R., Loewenstein D.A., Duara R., Rosselli M., Armstrong M.J., Rundek T., Hausman H.K., Dekosky S.T., Woods A.J, & Cohen R.A. (2021). Baseline Neuroimaging Predicts Decline to Dementia From Amnestic Mild Cognitive Impairment. Frontiers in Aging Neuroscience, 13, 758298.

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Relaxivity Measurements of Mn-PyC3A and Gd-DTPA

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Relaxivity measurements for Mn-PyC3A and Gd-DTPA in human plasma at 3T and 37 °C were performed using a clinical scanner (Siemens Skyra 3T MRI, Erlangen, Germany). Relaxivity was determined by plotting R1 as a function of agent concentration from 0.15 – 0.60 mM. R1 was measured on phantoms encased in a 37 °C thermal jacket using an inversion recovery spin echo sequence with 9 recovery times varying between 50 and 3000 ms.

Gale E.M., Wey H.Y., Ramsay I., Yen Y.F., Sosnovik D.E, & Caravan P. (2017). A Manganese-based Alternative to Gadolinium: Contrast-enhanced MR Angiography, Excretion, Pharmacokinetics, and Metabolism. Radiology, 286(3), 865-872.

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Cine PCMR for Cardiac Function Assessment

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Conventional cine PCMR was obtained to derive the subject-specific equations of fit in each healthy subject (male, ages 20–40) (n=10) and a patient (male, age 25) diagnosed with mild interpolated PVCs (n=1) (Eqn. 3) using a transverse slice, perpendicular to the direction of flow in the ascending aorta, to quantify the blood-flow volume and SV using a Siemens Skyra 3T MRI with the following parameters: VENC: 150 cm/s; TR/TE/flip: 37.00 ms/4.00 ms/15°; Field-of-View: 300 mm by 243 mm; Slick thickness: 3 mm. SV_PC was calculated from measured blood-flow by time-integration of measured blood flow across the aortic lumen within the region of interest (Eqn. 1). 12-lead ECG recordings were performed during a 20-second breath-hold to reduce artifacts associated with bulk patient motion and alterations in breathing patterns. Normal breathing patterns produced a minimal effect on acquired ECGs, with baseline variations being removed using a two-pole 0.05Hz to 0.67Hz linear digital high-pass filter with phase compensation to induce zero phase distortion as per AHA standards^{25 (link)}. 12-lead ECG and conventional cine PCMR baseline recordings were used to train the MLR equation to obtain fit coefficients (A₀, A₁, A₂ and A₃) at a resting heart rate.

Gregory T.S., Oshinski J., Schmidt E.J., Kwong R.Y., Stevenson W.G, & Tse Z.T. (2015). Continuous Rapid Quantification of Stroke Volume using Magnetohydrodynamic Voltages in 3T MRI. Circulation. Cardiovascular imaging, 8(12), 10.1161/CIRCIMAGING.115.003282 e003282.

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