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A939572

Manufactured by Bio-Techne
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The A939572 is a general-purpose laboratory centrifuge capable of handling a variety of sample types and volumes. It features programmable speed and time settings, and can accommodate multiple rotor types to suit different application needs. The product provides a reliable and efficient solution for common centrifugation tasks in research and clinical laboratory settings.

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Lab products found in correlation

Rotenone, by Selleck Chemicals (1 mentions) Gsk2194069, by Bio-Techne (1 mentions) Pf 05175157, by Bio-Techne (1 mentions) Fatty acid free bsa, by Merck Group (1 mentions) Oleic acid, by Merck Group (1 mentions)

2 protocols using a939572

1

Targeting Cellular Pathways with Compounds

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A939572 (Tocris 4845), GSK2194069 (Tocris 5303), PF-05175157 (Tocris 5790), and rotenone (Selleck Chemicals S2348) were used at the indicated concentrations.
Lien E.C., Westermark A.M., Zhang Y., Yuan C., Li Z., Lau A.N., Sapp K.M., Wolpin B.M, & Vander Heiden M.G. (2021). Low glycemic diets alter lipid metabolism to influence tumor growth. Nature, 599(7884), 302-307.
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2

Regulation of Lipid Metabolism by SCD1 Inhibitor

Cited 1 time
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A SCD1 inhibitor (A939572), 4-(2-chlorophenoxy)-N-[3-[(methylamino)carbonyl] phenyl]-1-piperidinecarboxamide (Tocris) was dissolved in dimethylsulfoxide (DMSO) and added to the culture medium (20 μM at a final concentration). Oleic acid (18:1, O1008), stearic acid (18:0, S4751), and fatty acid free-BSA (A8806) were purchased from Sigma. BSA-conjugated fatty acids were prepared by diluting 50 mM stock fatty acids in DMSO with 100 mg/ml BSA in 1x PBS to produce a 3 mM working solution.29 (link) Cells were then treated with a final concentration of 30 μM BSA-conjugated fatty acid (a final concentration of 0.1% BSA). Cells were treated with or without A939572 or 30 μM of fatty acid for 16 hours.
Skrypek K., Balog S., Eriguchi Y, & Asahina K. (2021). Inhibition of Stearoyl-CoA Desaturase Induces the Unfolded Protein Response in Pancreatic Tumors and Suppresses Their Growth. Pancreas, 50(2), 219-226.
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