Signa hd

Manufactured by GE Healthcare

Sourced in United States, Germany

The Signa HD is a magnetic resonance imaging (MRI) system developed by GE Healthcare. It is designed to deliver high-quality images for diagnostic purposes. The Signa HD provides advanced imaging capabilities, but a detailed description of its core function is not available while maintaining an unbiased and factual approach.

Automatically generated - may contain errors

Lab products found in correlation

40 protocols using signa hd

Multimodal Breast Imaging Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols

For all patients enrolled in this study, images were obtained respectively with two MRI scanners, a 3.0-T MRI scanner (Philips Achieva, Center 1) and a 1.5-T scanner (GE Signa HD, Center 2). All patients were positioned in the prone position and scanned with a bilateral dedicated breast coil. T2WI, T1WI, diffusion-weighted imaging (DWI), pre-contrast-enhancement T1WI, and DCE were sequentially acquired. Gd-DTPA (Magnevist) was used as the contrast agent in both centers. Pre-contrast-enhancement T1WI was obtained prior to contrast agent injection. For the DCE sequence, six phases (Center 1) and seven phases (Center 2) were acquired after the end of high-pressure syringe injection with 60 s (Center 1) and 70 s (Center 2) per phase, respectively. In both centers, Gd-DTPA was intravenously injected at a dose of 0.1 mmol/kg and at a flow rate of 2 ml/s, and 20–30 ml of saline flush was subsequently injected at the same flow rate. Detailed parameters are listed in Supplementary Table S2.

Zhang S., Wang X., Yang Z., Zhu Y., Zhao N., Li Y., He J., Sun H, & Xie Z. (2022). Intra- and Peritumoral Radiomics Model Based on Early DCE-MRI for Preoperative Prediction of Molecular Subtypes in Invasive Ductal Breast Carcinoma: A Multitask Machine Learning Study. Frontiers in Oncology, 12, 905551.

+ Open protocol

+ Expand

Functional Brain Imaging Protocol: 3T MRI

Check if the same lab product or an alternative is used in the 5 most similar protocols

Axially oriented functional images were obtained by a 3T Signa HD MR scanner (GE Healthcare, Waukesha, WI) using an echo‐planar‐imaging gradient‐echo sequence and an eight channel head coil (TR = 2000 ms, TE = 22 ms, flip angle = 75°, matrix size = 64 × 64 pixels, 36 slices, 4 × 4 mm in plane resolution, spacing between slices = 4 mm, slice thickness = 3.3 mm, interleaved acquisition). The slices were aligned to the anterior commissure‐posterior commissure line and covered the whole brain. Functional scanning was preceded by 18 s of dummy scans to ensure tissue steady‐state magnetization. A total of 210 volumes were taken during each of the two runs (pretraining evaluation/post‐training evaluation) for every participant. High resolution sagittally oriented anatomical images were also collected for anatomical reference. A 3D fast spoiled‐gradient‐recalled pulse sequence was obtained (TR = 8.8 ms, TE = 1.7 ms, flip angle = 10°, matrix size = 256 × 256 pixels, 1 × 1 mm in plane resolution, spacing between slices = 1 mm plus 0 mm interslice gap, slice thickness = 1 mm).

Modroño C., Socas R., Hernández‐Martín E., Plata‐Bello J., Marcano F., Pérez‐González J.M, & González‐Mora J.L. (2020). Neurofunctional correlates of eye to hand motor transfer. Human Brain Mapping, 41(10), 2656-2668.

+ Open protocol

+ Expand

Meniscal Allograft Graft Extrusion and Lateral Cartilage Assessment

Cited 1 time

Check if the same lab product or an alternative is used in the 5 most similar protocols

To assess extrusion of the meniscal allograft and the cartilage status of the lateral compartment, we performed a follow-up MRI at 2 days and 12 months postoperatively. Patients signed an informed consent form before undergoing MRI using a 3.0-T system (Signa HD; GE Healthcare). Analysis was performed using the cross-link tool of the PACS workstation. Graft extrusion in the coronal plane was assessed by measuring the distance from the lateral margin of the graft to the superolateral aspect of the tibial plateau. Pathological extrusion was defined as graft extrusion ≥3 mm (Figure 2).^{3 (link),5 (link),13 (link),24 (link),25 (link)} Patients were categorized into pathological and nonpathological extrusion subgroups based on MRI findings at 1 year postoperatively.
The cartilage status in the lateral compartment was assessed according to the modified Outerbridge grade (grade 0, normal; grade 1, cartilage surface fibrillation; grade 2, <50% loss of cartilage thickness; grade 3, >50% loss of cartilage thickness; grade 4, exposed subchondral bone).^{6 (link),12 (link),29 (link)} The worst areas of cartilage loss (Outerbridge grade ≥3) of the lateral femoral condyle (LFC) and the lateral tibial plateau (LTP) were reported to determine the overall status of the corresponding articular cartilage.^{23 (link)}

Lee D.W., Lee D.R., Kim M.A., Lee J.K, & Kim J.G. (2022). Effect of Preoperative Joint Space Width on Lateral Meniscal Allograft Transplantation: Outcomes at Midterm Follow-up. Orthopaedic Journal of Sports Medicine, 10(9), 23259671221103845.

+ Open protocol

+ Expand

Multimodal Neuroimaging in Alzheimer's Disease

Check if the same lab product or an alternative is used in the 5 most similar protocols

All participants underwent structural MRI with a 3.0-T GE scanner (Signa HD, WI, USA) and a standard GE quadrature head coil. The MRI and PET/CT examinations were performed within one week. The scan protocol included a high-resolution 3D T1-weighted spoiled gradient recalled echo sequence (TR = 7.0 ms, TE = 2.9 ms, Inversion time = 450 ms, thickness = 1.2 mm, matrix = 256 × 256, FOV = 240 mm, and in plane resolution = 0.9 × 0.9 mm²) to produce contiguous sagittal anatomic images for subsequent spatial normalization and coregistration.
The preprocessing of MRI and PET imaging is detailed elsewhere [10 (link)]. Specifically, all structural MRI images were segmented into gray matter, white matter, and cerebrospinal fluid and then used to construct a population template using DARTEL of SPM8 (http://www.fil.ion.ucl.ac.uk/spm). The mid-frame (the 16th frame) of the dynamic PIB images and FDG images was coregistered with the corresponding MRI scan, and the PET scans were transformed to the population template with the deformation fields generated in the registration procedure of the MRI scans. Finally, all images were spatially normalized to the Montreal Neurological Institute space.

Fu L., Liu L., Zhang J., Xu B., Fan Y, & Tian J. (2018). Brain Network Alterations in Alzheimer's Disease Identified by Early-Phase PIB-PET. Contrast Media & Molecular Imaging, 2018, 6830105.

+ Open protocol

+ Expand

Preoperative Neuroimaging for Brain Glioma

Check if the same lab product or an alternative is used in the 5 most similar protocols

In all cases, preoperative MRI was performed, including gadolinium contrast-enhanced imaging and diffusion-weighted imaging with long-associative tract reconstruction by high angular resolution (3.0 T MRI scanner General Electric Signa HD with 8-channel head coil) to determine if cortical tracts were infiltrated by the tumor. Diffusion tensor imaging protocol included TR = 15,000 ms, TE = minimum, matrix 96 × 96, and FOV = 24 cm, and contained one scan series with b = 1000 and 60 diffusion gradient directions. Processing was carried out using Advantage workstation and READY View software (both from GE Healthcare, Waukesha, WI, USA). Preoperative functional MRI was performed in 20 cases. EOR was defined based on the assessment of pre- and postoperative T1 contrast-enhanced sequences for glioblastomas or T2 FLAIR data for non-contrast-enhancing gliomas. Image assessment was performed by an independent radiologist. Preoperative PET of the brain was not a routine procedure for patients with brain gliomas and was performed only in eight patients.

Goryaynov S.A., Buklina S.B., Khapov I.V., Batalov A.I., Potapov A.A., Pronin I.N., Belyaev A.U., Aristov A.A., Zhukov V.U., Pavlova G.V, & Belykh E. (2022). 5-ALA-guided tumor resection during awake speech mapping in gliomas located in eloquent speech areas: Single-center experience. Frontiers in Oncology, 12, 940951.

+ Open protocol

+ Expand

Multimodal Imaging of Liver Steatosis

Check if the same lab product or an alternative is used in the 5 most similar protocols

Non-contrast chest CTs were obtained in the supine position in a single breath-hold on several CT platforms (Lightspeed Ultra, Lightspeed VCT, Discovery CT750HD, and Revolution, GE Healthcare; Somatom Definition Flash, Somatom Definition AS, Sensation Cardiac 64, and Force, Siemens Healthineers) using clinical acquisition protocols: 100 or 120 kVp, 106–663 mA, 0.600 mm (Siemens), 0.625 or 1.25 mm (GE) collimation, slice thickness 1.00–3.00 mm, and reconstruction kernels of B40f for Somatom Definition AS and Sensation Cardiac 64, I31f for Somatom Definition Flash, and standard for all GE scanners. Liver attenuation on CT was measured in HU on mediastinal window settings (width 350 HU; level 25 HU).
Multichannel MRI systems were used for all patients (1.5T: Avanto, Aera, and Sonata, Siemens Healthineers; and Signa HD and Optima 450w, GE Medical Systems or 3T: Skyra and Biograph mMR, Siemens Healthineers; and Discovery 750, GE Medical Systems) [27 ]. The liver MRI sequences and acquisition parameters followed clinical protocols. T1WI in- and out-of-phase imaging was performed in all cases and used to calculate the fat fraction percentage (FF).

Jirapatnakul A., Reeves A.P., Lewis S., Chen X., Ma T., Yip R., Chin X., Liu S., Perumalswami P.V., Yankelevitz D.F., Crane M., Branch A.D, & Henschke C.I. (2019). Automated measurement of liver attenuation to identify moderate-to-severe hepatic steatosis from chest CT scans. European journal of radiology, 122, 108723.

+ Open protocol

+ Expand

Functional Brain Imaging using 3T MRI

Check if the same lab product or an alternative is used in the 5 most similar protocols

Axially oriented functional images were obtained by a 3T Signa HD MR scanner (GE Healthcare, Waukesha, WI, USA) using an echo-planar-imaging gradient-echo sequence and an 8 channel head coil (TR = 2000 msec, TE = 22 msec, flip angle = 75°, matrix size = 64 x 64 pixels, 36 slices, 4 x 4 mm in plane resolution, spacing between slices = 4 mm, slice thickness = 3.3 mm, interleaved acquisition). The head was stabilized with foam pads. The slices were aligned to the anterior commissure—posterior commissure line and covered the whole brain. Functional scanning was preceded by 18 seconds of dummy scans to ensure tissue steady-state magnetization. 241 volumes were taken during each of the two runs for every participant. High resolution sagittally oriented anatomical images were also collected for anatomical reference. A 3D fast spoiled-gradient-recalled pulse sequence was obtained (TR = 6 msec, TE = 1 msec, flip angle = 12°, matrix size = 256 x 256 pixels, .98 x .98 mm in plane resolution, spacing between slices = 1 mm, slice thickness = 1 mm).

Modroño C., Plata-Bello J., Zelaya F., García S., Galván I., Marcano F., Navarrete G., Casanova Ó., Mas M, & González-Mora J.L. (2015). Enhancing Sensorimotor Activity by Controlling Virtual Objects with Gaze. PLoS ONE, 10(3), e0121562.

+ Open protocol

+ Expand

Dynamic Contrast-Enhanced Liver MRI Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols

MRI was performed with extracellular contrast agents (gadobenate dimeglumine, 0.1 mmol/kg) with a dynamic contrast-enhanced liver protocol performed on 1.5-T (Ingenia, Philips Healthcare; Signa HD, GE Healthcare, Science Park, Amsterdam, The Netherlands) or 3-T (Ingenia, Philips Healthcare; Discovery MR750, GE Healthcare) imaging platforms. Early arterial phase images were obtained 20–25 s after gadolinium-based IV contrast administration; late arterial phase images were obtained 35–45 s after contrast administration; portal venous phase images were obtained 80–90 s after contrast administration; and delayed phase images were obtained 3 min after contrast administration.

Kim C., Cigarroa N., Surabhi V., Ganeshan B, & Pillai A.K. (2020). Retrospective CT/MRI Texture Analysis of Rapidly Progressive Hepatocellular Carcinoma. Journal of Personalized Medicine, 10(3), 136.

+ Open protocol

+ Expand

Dual-Echo DWI for Stroke Diagnosis

Check if the same lab product or an alternative is used in the 5 most similar protocols

All data were acquired on an inpatient 1.5T MR imaging system (Signa HD; GE Healthcare, Milwaukee, Wisconsin) equipped with an 8-channel head coil. With institutional review board approval, 50 consecutive adult patients who were clinically suspected of stroke were scanned with the dual-echo DWI sequence between January 13, 2011, and April 6, 2011. The product DWI sequence used as part of standard of care at our institution was used as the criterion standard comparison DWI sequence for this study. We also acquired additional routine MR images relevant to the clinical scenario: T2-weighted FLAIR, T2-weighted gradient-recalled echo (GRE), fast spin-echo, MRA of the circle of Willis, and bolus perfusion imaging. The final clinical diagnosis was based on the imaging findings that were correlated with appropriate clinical symptoms (Table 1).

Holdsworth S.J., Yeom K.W., Antonucci M.U., Andre J.B., Rosenberg J., Aksoy M., Straka M., Fischbein N.J., Bammer R., Moseley M.E., Zaharchuk G, & Skare S. (2014). Diffusion-Weighted Imaging with Dual-Echo Echo-Planar Imaging for Better Sensitivity to Acute Stroke. AJNR: American Journal of Neuroradiology, 35(7), 1293-1302.

+ Open protocol

+ Expand

Diffusion-Weighted MRI Protocol for Brain Imaging

Check if the same lab product or an alternative is used in the 5 most similar protocols

A diffusion-weighted MRI (DW-MRI) scanning session was run on a 1.5 T scanner (General Electric Signa HD). Images were acquired with a spin-echo EPI sequence (53 axial slices, TR: 15000 ms, TE: 104 ms, acquisition matrix: 256 × 256, voxel size: 0.94 × 0.94 × 2.5 mm³). A run with one non-diffusion weighted volume (using a spin-echo EPI sequence coverage of the whole head) and 25 diffusion-weighted volumes (non-collinear diffusion gradient directions, b-values of 1500 s/mm²) was acquired.

González M.J., Polo M.R., Ripollés P., Gassió R., Ormazabal A., Sierra C., Roura R.C., Artuch R, & Campistol J. (2018). White matter microstructural damage in early treated phenylketonuric patients. Orphanet Journal of Rare Diseases, 13, 188.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!