Megalign expert software

Manufactured by DNASTAR

Sourced in United States

MegAlign-expert software is a bioinformatics tool developed by DNASTAR for multiple sequence alignment and phylogenetic analysis. It provides a user-friendly interface for aligning DNA, RNA, or protein sequences and generating phylogenetic trees.

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MegAlign (202 citations) MegAlign software (59 citations)

2 protocols using megalign expert software

CSFV E2 Protein Domain Alignment

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The E2 amino acid sequences comprising residues 690 to 738 (representing the domain B/C of the CSFV E2 protein) of the pestiviruses that were analyzed in the current study were obtained from the National Center for Biotechnology Information (NCBI) or from the CSF database of the EU and OIE Reference Laboratory for CSF [49 (link)]. Protein alignment of these sequences was generated by using the Clustal W method of MegAlign-expert software (DNASTAR, Madison, WI, USA).

Huang Y.L., Meyer D., Postel A., Tsai K.J., Liu H.M., Yang C.H., Huang Y.C., Berkley N., Deng M.C., Wang F.I., Becher P., Crooke H, & Chang C.Y. (2021). Identification of a Common Conformational Epitope on the Glycoprotein E2 of Classical Swine Fever Virus and Border Disease Virus. Viruses, 13(8), 1655.

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Pestivirus E2 Protein Domain Alignment

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The E2 amino acid sequences spanning residues 780–868 (the domain D/A of the CSFV E2 protein) of the pestiviruses were obtained from the National Center for Biotechnology Information (NCBI) or from the CSF database of the EU and WOAH Reference Laboratory for CSF (Postel et al., 2016 ). Amino acid sequences were aligned by using the Clustal W method of MegAlign-expert software (DNASTAR, Madison, WI, USA).

Huang Y.L., Meyer D., Postel A., Tsai K.J., Liu H.M., Yang C.H., Huang Y.C., Chang H.W., Deng M.C., Wang F.I., Becher P., Crooke H, & Chang C.Y. (2023). Identification of neutralizing epitopes on the D/A domain of the E2 glycoprotein of classical swine fever virus. Virus Research, 336, 199209.

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