We first summarized the baseline characteristics of participants using means and standard deviations (SDs) or frequencies and percentages. We compared participants who did with those who did not experience any injurious fall using t-tests or Wilcoxon rank-sum tests for continuous variables and Chi-squared or Fisher’s exact tests for categorical variables.
Subsequently, we performed conditional logistic regression, using injurious fall as the dependent variable. We began with univariate regression and independent variables with
p < 0.10 were included in the multivariate regression models. We performed two multivariate conditional logistic regressions, using the number of anti-hypertensive medication classes or any change in anti-hypertensive medication as the exposure variables respectively. Associations with
p < 0.05 in the multivariate regressions were regarded as statistically significant. To examine whether the results were consistent in parsimonious models, we also performed sensitivity analyses by including variables with
p < 0.10 into both forward and backward stepwise regressions. We specified
p > 0.10 for removal from the model and
p < 0.05 for addition to the model. We examined all final models for collinearity using variance inflation factor (VIF). All analyses were performed using
STATA SE version 14.0 (StataCorp College Station, Texas).
Banu Z., Lim K.K., Kwan Y.H., Yap K.Z., Ang H.T., Tan C.S., Fong W., Thumboo J., Lee K.H., Ostbye T, & Low L.L. (2018). Anti-hypertensive medications and injurious falls in an older population of low socioeconomic status: a nested case-control study. BMC Geriatrics, 18, 195.