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Ge 3t signa hdx mr scanner

Manufactured by GE Healthcare

The GE 3T Signa® HDx MR scanner is a high-field magnetic resonance imaging (MRI) system that operates at a magnetic field strength of 3 Tesla. It is designed to capture detailed images of the body's internal structures and functions.

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5 protocols using ge 3t signa hdx mr scanner

1

Multimodal MRI Acquisition Protocol

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All MRI scans were acquired on a GE 3T Signa® HDx MR scanner (GE Healthcare) with an 8-channel head coil. During each session, 180 T1-weighted 1-mm3 isotropic volumetric inversion recovery fast spoiled gradient-recalled images, with CSF suppressed, were obtained to cover the whole brain with the following parameters: time of echo = 3.8 ms, time of repetition of acquisition = 8.6 ms, time of inversion = 831 ms, repetition time of inversion = 2332 ms, flip angle = 8°, and receiver bandwidth = ±20.8 kHz.
After the T1 data acquisition, first and high-order shimming procedures were carried out to improve magnetic field homogeneity. The DTI data were acquired with a dual spin-echo echo-planar imaging sequence for 12 minutes and 6 seconds with the following parameters: 48 contiguous 2.4-mm axial slices in an interleaved order, field of view = 22 × 22 cm, matrix size = 128 × 128, number of excitations = 2, echo time = 77.5 ms, repetition time = 13.7 s, 25 diffusion-weighted volumes (one per gradient direction) with b = 1000 s/mm2, one volume with b = 0 and parallel imaging acceleration factor = 2. One staff member sat inside the scanner room next to the child at all times to monitor the child’s comfort and to ensure cooperation during scanning. During acquisition of volumetric T1-weighted scans and DTI scans, the children viewed a movie to help them stay still.
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2

Functional and Anatomical Brain Imaging Protocol

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Functional and anatomical MR images were acquired on a GE 3 T Signa® HDx MR scanner (GE Healthcare) with an 8-channel head coil. Functional images were acquired using echo-planar sequence with the following parameters: 38 contiguous 3 mm axial slices in an ascending, interleaved order, echo time = 27.7 ms, repetition time = 2500 ms, flip angle = 80°, field of view = 22 cm, matrix size = 64 × 64, ramp sampling. In total, 164 volumes were acquired during wakeful rest with subjects' eyes closed. Whole brain anatomical images were acquired using inversion recovery fast spoiled gradient recalled echo sequence with CSF suppressed, time of echo = 3.8 ms, time of repetition of acquisition = 8.6 ms, time of inversion = 831 ms, repetition time of inversion = 2332 ms, flip angle = 8°, field of view = 25.6 cm × 25.6 cm, matrix size = 256 × 256, slice thickness = 1 mm, and receiver bandwidth = ± 20.8 kHz. During the scans, one staff member sat inside the scanner room next to the child at all times to monitor the child's comfort and to ensure cooperation during scanning.
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3

Pediatric Brain Imaging: Resting-state fMRI

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During the rsfMRI scan, children lay supine with their eyes open. They were instructed to remain as still as possible. Preceding the MRI scanning session, all children were trained during a separate visit with a mock scanner to familiarize and desensitize them to the sights and sounds of the scanner and to practice being still inside the scanner bore (Chang & Zhu, 2015 (link); Chang et al., 2016 (link)). To ensure that the child remained calm and to minimize the possibility of movement, an experimenter sat by the child throughout the duration of the scan. All MRI scans were acquired on a GE 3T Signa HDx MR scanner (GE Healthcare) with an 8-channel head coil. During each session, 180 T1-weighted 1-mm3 isotropic volumetric inversion recovery fast spoiled gradient-recalled images (3D IRFSPGR) (10 min scan time), with CSF suppressed, were obtained to cover the whole brain with the following parameters: time of echo = 3.8 ms, time 2332 ms, flip angle = 8°, field of view = 25.6 cm × 25.6 cm, matrix size = 256 × 256, slice thickness = 1 mm, and receiver bandwidth = 20.8 kHz.
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4

Multimodal Neuroimaging Protocol for Brain Mapping

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Functional brain images were acquired on a GE 3T Signa® HDx MR scanner (GE Healthcare, Waukesha, WI) with an 8-channel head coil using a gradient echo Echo-Planar-Imaging pulse sequence with these parameters: 38 contiguous axial slices, slice thickness = 3 mm, TE (time of echo) /TR (time of repetition) = 28/2500 ms, flip angle 80°, FOV (field of view) = 220 mm, matrix size = 64×64, and first 4 time points discarded. To identify anatomical regions, 180 sagittal T1-weighted 1 mm3 isotropic volumetric inversion recovery fast spoiled gradient-recalled images (10-min scan time), with cerebrospinal fluid (CSF) suppressed, were obtained to cover the whole brain with the following parameters: TE/TR = 3.8/8.6 ms, time of inversion = 831 ms, TR of inversion = 2332 ms, flip angle = 8°, FOV =25.6 cm×25.6 cm, matrix size = 256×256, slice thickness = 1 mm, receiver bandwidth =±20.8 kHz). For more details, please refer to our previous studies [32, 40 (link)].
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5

In Vivo 3D Blood Vessel Modeling

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This study was approved by the Internal Review Board at Michigan State University.
Two individual subjects (one healthy subject and one patient with carotid artery stenosis) were scanned on a GE 3T Signa® HDx MR scanner (GE Healthcare, Waukesha, WI). Time of flight (TOF) MRI scans were extracted from the set of 3D images and imported to an image processing software package, MIMICS® (Materialize, Leuven, Belgium). Using thresholding and region growing segmentation techniques, geometrical solid models of blood vessels are constructed. After the initial segmentation, the 3D model underwent several steps of smoothening. Finally, 3D blood vessel models were transferred to an automatic mesh generator.
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