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Ceftizoxime

Manufactured by Mast Group
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Ceftizoxime is a third-generation cephalosporin antibiotic used in laboratory settings. It is a broad-spectrum antimicrobial agent effective against a variety of gram-positive and gram-negative bacteria.

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Lab products found in correlation

Ceftazidime, by Mast Group (3 mentions) Cefotaxime, by Mast Group (3 mentions) Amikacin, by Mast Group (3 mentions) Gentamicin, by Mast Group (3 mentions) Imipenem, by Mast Group (3 mentions) Ciprofloxacin, by Mast Group (2 mentions) Meropenem, by Mast Group (2 mentions) Ceftriaxone, by Mast Group (1 mentions) Chloramphenicol, by Mast Group (1 mentions) Ampicillin, by Mast Group (1 mentions) Penicillin, by Mast Group (1 mentions) Oxacillin, by Mast Group (1 mentions) Vancomycin, by Mast Group (1 mentions) Rifampicin, by Mast Group (1 mentions) Erythromycin, by Mast Group (1 mentions) Co trimoxazole, by Mast Group (1 mentions) Cefoxitin, by Mast Group (1 mentions) Norfloxacin, by Mast Group (1 mentions) Cefepime, by Mast Group (1 mentions) Ertapenem, by Mast Group (1 mentions)

3 protocols using ceftizoxime

1

Antimicrobial Resistance Profiling

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All isolates were examined for resistance to routine antimicrobial agents by standard disk diffusion method using Staphylococcus aureus (ATCC 25923) and Escherichia coli (ATCC 25922) as control strains (17 ). The antibiotics tested were gentamicin, amikacin, ceftazidime, ceftizoxime, cefotaxime, ceftriaxone, imipenem, ciprofloxacin, co-trimoxazole, chloramphenicol, penicillin, oxacillin, ampicillin, vancomycin, rifampicin and erythromycin (Mast Co, the UK). Isolates showing intermediate levels of susceptibility were classified as nonsusceptible.
Abdinia B., Ahangarzadeh Rezaee M, & Abdoli Oskouie S. (2014). Etiology and Antimicrobial Resistance Patterns of Acute Bacterial Meningitis in Children: A 10-Year Referral Hospital-Based Study in Northwest Iran. Iranian Red Crescent Medical Journal, 16(7), e17616.
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2

Antibacterial Susceptibility Testing Protocol

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Antibacterial susceptibility test of isolates to cefepime (30 µg), cefotaxime (30 µg), cefoxitin (30 µg), ceftazidime (30 µg), ceftizoxime (30 µg), cefpodoxime (10 µg), imipenem (10 µg), meropenem (10 µg), ertapenem (10 µg), gentamicin (10 µg), amikacin (30 µg), ciprofloxacin (5 µg), and norfloxacin (10 µg) (Mast Group Ltd., Bootle, UK) was determined by disk diffusion method on Müller–Hinton agar media (Laboratorios CONDA, Madrid, Spain) according to the Clinical and Laboratory Standards Institute (CLSI).12 Minimum inhibitory concentration (MIC) of isolates to cefotaxime, cefepime, and imipenem was determined by microbroth dilution method according to CLSI. To determine MIC of colistin and tigecycline by microbroth dilution method, we used the European Committee on Antimicrobial Susceptibility Testing recommendations (http://www.eucast. org/clinical-breakpoints). Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 27853 were used as standard strains in antibacterial susceptibility testing.
Kiaei S., Moradi M., Hosseini-Nave H., Ziasistani M, & Kalantar-Neyestanaki D. (2018). Endemic dissemination of different sequence types of carbapenem-resistant Klebsiella pneumoniae strains harboring blaNDM and 16S rRNA methylase genes in Kerman hospitals, Iran, from 2015 to 2017. Infection and Drug Resistance, 12, 45-54.
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3

Antibiotic Susceptibility Profiling of Isolates

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The susceptibility pattern of isolates to different antibiotics were examined using disk diffusion method (Kirby-Bauer) on Muller-Hinton agar plates according to guidelines of CLSI (10 ). The antimicrobial disks were included: imipenem (10μg), meropenem (10μg), ceftazidime (30μg), carbenicillin (100μg), tobramicin (10μg), amikacin (30μg), ticarcillin (75μg), gentamicin (10μg), cefotaxime (30μg), and ceftizoxime (30μg) (MAST Co. UK). Pseudomonas aeruginosa ATCC27853 were used as a control strain (11 ).
Moosavian M, & Rahimzadeh M. (2015). Molecular detection of metallo-β-lactamase genes, blaIMP-1, blaVIM-2 and blaSPM-1 in imipenem resistant Pseudomonas aeruginosa isolated from clinical specimens in teaching hospitals of Ahvaz, Iran. Iranian Journal of Microbiology, 7(1), 2-6.
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