The sodium salt of MTK was obtained from KyongBo Pharmaceutical Co. Ltd. (Asan, South Korea). MTK and zafirlukast analytical standards were used as internal standards for LC-MS/MS. Polysorbate 80 (P80), tyloxapol, polyethylene glycol 4000 (PEG 4000), sodium carboxymethylcellulose (Na CMC), polyvinylpyrrolidone (PVP K17), acetic acid, sodium acetate, lactic acid, sodium lactate, and phosphate-buffered saline tablets were purchased from Sigma Chemical Co. (St. Louis, MO, USA). Polyoxyl 15 hydroxy stearate (Kolliphor HS15), polyoxyl-35 castor oil (Kolliphor EL), and polyoxyl 40 hydrogenated castor oil (Kolliphor RH40) were provided by BASF (Ludwigshafen, Germany). HPLC-grade acetonitrile and methanol were purchased from J. T. Baker (Phillipsburg, NJ, USA). All other chemicals were of analytical grade and used without further refinement.
Polyoxyl 35 castor oil
Manufactured by BASF
Sourced in Germany
Polyoxyl 35 castor oil is a laboratory-grade surfactant and emulsifier. It is a non-ionic, water-soluble compound derived from castor oil and ethylene oxide. The primary function of Polyoxyl 35 castor oil is to facilitate the formation and stabilization of emulsions and dispersions in various laboratory applications.
Automatically generated - may contain errors
Lab products found in correlation
Kolliphor rh40, by BASF (2 mentions)
Sodium acetate, by Merck Group (1 mentions)
Lactic acid, by Merck Group (1 mentions)
Phosphate buffered saline tablet, by Merck Group (1 mentions)
Sodium lactate, by Merck Group (1 mentions)
Kolliphor hs 15, by BASF (1 mentions)
Triethanolamine, by HiMedia (1 mentions)
Methylparaben, by HiMedia (1 mentions)
Propyl paraben, by HiMedia (1 mentions)
Lipo2000, by Thermo Fisher Scientific (1 mentions)
Jetpei, by Polyplus Transfection (1 mentions)
Oleic acid, by Gattefosse (1 mentions)
Cremophor el, by BASF (1 mentions)
Hplc grade methanol, by Avantor (1 mentions)
Potassium phosphate dibasic, by Merck Group (1 mentions)
Triethylamine, by Merck Group (1 mentions)
Peanut oil, by Merck Group (1 mentions)
Soybean oil, by Merck Group (1 mentions)
Sodium metabisulfite, by Daejung Chemicals (1 mentions)
Milli q, by Merck Group (1 mentions)
6 protocols using polyoxyl 35 castor oil
1
Quantitative LC-MS/MS Analysis of MTK
2
Curcumin Loaded Topical Nanoemulsion
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The supplier of curcumin (CMN) was obtained from SRL Pvt. Ltd, Maharashtra, India. Cremophor EL 100 (Cre-EL), also known as Polyoxyl 35 Castor Oil (BASF Corporation, Mumbai, India), glyceryl monooleate (GMO), and polyethylene glycol 5000 (PEG 5000), and Propylene glycol (PG) procured from S.D. Fine Chem. Pvt. Ltd, Mumbai, India. Triethanolamine, Glycerine, methylparaben, and propylparaben were purchased from Hi Media, Mumbai, India. Analytical grade chemicals, reagents, and internally prepared double distilled water were used in this research.
3
Optimized siRNA Delivery System
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Span80, Span85, Tween80, Soybean oil, Squalene (Aladdin, China). Lecithin (A.V.T. Pharmaceutical, Shanghai). Oleic acid, medium chain triglyceride (MCT) were provided by GATTEFOSSé (Paris, France). RH40, Polyoxyl 35 castor oil (Cremophor®EL) were purchased from BASF (Ludwigshafen, Germany). Glycerol and Propylene glycol were provided by Fagron Nordic A/S (Rotterdam, The Netherlands). All other reagents were of pharmaceutical grade. Reagents for cell culture were provided by Gibco (Montpellier, France).
A 21-base pair siRNA oligonucleoside duplex for silencing B2M gene was synthesized by the help of ‘siRNA Explorer’ and dissolved in diethylpyrocarbonate (DEPC)-treated water before use. The gene sequence was confirmed by HPLC-MS and gel electrophoresis comprehensively. The gene silencing efficiency was verified in vitro. Jet-PEI was provided by Polyplus Company. Lipo2000 was provided by Invitrogen Company.
NIH female mice (8 weeks, 20 ∼ 28 g) in estrous phase were provided by Guangdong Medical Experimental Animal Center (China). The study protocol was reviewed and approved by the Animal Welfare and Ethics Committee of Tsinghua University.
A 21-base pair siRNA oligonucleoside duplex for silencing B2M gene was synthesized by the help of ‘siRNA Explorer’ and dissolved in diethylpyrocarbonate (DEPC)-treated water before use. The gene sequence was confirmed by HPLC-MS and gel electrophoresis comprehensively. The gene silencing efficiency was verified in vitro. Jet-PEI was provided by Polyplus Company. Lipo2000 was provided by Invitrogen Company.
NIH female mice (8 weeks, 20 ∼ 28 g) in estrous phase were provided by Guangdong Medical Experimental Animal Center (China). The study protocol was reviewed and approved by the Animal Welfare and Ethics Committee of Tsinghua University.
4
Formulation and Characterization of RTG-based Lipid Delivery System
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The RTG-free base was obtained from Ferrer Pharmaceutical Co., Ltd. (Barcelona, Spain). Sodium carboxymethyl cellulose (Na. CMC), polyethylene glycol 4000 (PEG 4000), soybean oil, corn oil, peanut oil, potassium phosphate dibasic, and triethylamine were purchased from Sigma-Aldrich (St. Louis, MO, USA). Polysorbate 80, castor oil, and cottonseed oil were provided by Croda Korea (Seoul, Korea). Polyoxyethylene (160), polyoxypropylene (30) glycol (Poloxamer 188), polyoxyl 15 hydroxystearate (Kolliphor HS 15), polyoxyl 40 hydrogenated castor oil (Kolliphor RH 40), polyoxyl 35 castor oil (Kolliphor EL), and polyvinylpyrrolidone K17 (PVP K17) were provided by BASF (Ludwigshafen, Germany). Medium-chain triglycerides (Miglyol 810N) and tricaprylin (Captex 8000) were obtained from IOI Oleo GmbH (Witten, Germany) and Abitec Corporation (Columbus, OH, USA), respectively. Sodium metabisulfite was purchased from Daejung Chemicals & Metals (Siheung-si, Korea). HPLC-grade methanol was purchased from J.T. Baker (Phillipsburg, NJ, USA). All other reagents or chemicals were of analytical grade and were employed without further purification.
5
Topical Cyclosporine A Formulation
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CsA was obtained from Concord Drugs Ltd (Hyderabad, India). Polyoxyl 35 castor oil (Cremophor EL) was generously gifted by BASF Co Ltd (Ludwigshafen, Germany). Glycerin (purity 99%), ethanol (purity 99.9%), sodium phosphate dibasic (anhydrous), sodium phosphate monobasic (anhydrous), and high-performance liquid chromatography (HPLC)-grade acetonitrile were purchased from Samchun Pure Chemical Co Ltd (Pyeongtaek, South Korea). Restasis emulsion was purchased from a local market. Atropine sulfate (AS) and hematoxylin and eosin (H&E) were purchased from Sigma-Aldrich (St Louis, MO, USA). Purified water (Milli-Q; EMD Millipore, Billerica, MA, USA) was used through the study. All other chemicals used were of analytical grade.
6
Amoxicillin Trihydrate Formulation and Characterization
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Amoxicillin tryhydrate was supplied by the United Laboratories Co., Ltd (ZhuHai, China). The working standard of amoxicillin trihydrate (85.8% purity) and ampicillin trihydrate (Internal standard, IS) (Fig 1 ) were obtained from National institutes for food and drug control (Beijing, China). Eudragit L30 D-55 was received as a gift sample from Rohm Pharmaceutical Co., Ltd (Shanghai, China). HPMCAS was given by ShinEtsu Chemical Co., Ltd. (Tokyo, Japan). Microcrystalline cellulose (MCC, Avicel® PH 101, PH 102, PH 301) were from Asahi Kasei Corporation in Japan. Triethyl citrate (TEC) was given by AnHui BBCA Pharmaceutical Co., Ltd (AnHui, China). Polyplasdone (PVPP, Ashalnd, USA) was given from Industrial Polychemical Service Corporation (NewJersey, USA). Sodium hydroxide (GR grade), sodium lauryl sulfate (GR grade), sodium dihydrogen phosphate (GR grade) and phosphoric acid (GR grade) and glacial acetic acid (GR grade) were purchased from Sinopharm Chemical Reagent Co., Ltd (Shanghai, China). Methanol (HPLC grade) and acetonitrile (HPLC grade) were purchased from Merck Pvt. Ltd. (Shanghai, China). Polyoxyl 35 castor oil was purchased from BASF (Germany). Hydroxypropyl methyl cellulose (HPMC E5) and Opadry® were purchased from Colorcon (Shanghai, China).
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