Berbamine (BBM), Mitomycin C, Pluronic F-127, poly (ethylene glycol)-10,000 (PEG – 10,000), Rhodamine 123, Tween-80, propidium iodide (PI), 6-coumarin, protease inhibitor cocktail, sodium dodecyl sulphate (SDS), glycine, 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyl tetrazolium bromide (MTT), D-α-Tocopherol poly (ethylene glycol) 1000 succinate (TPGS), bradford reagent, triethyl amine (TEA), crystal violet, gelatin, brilliant blue G, p-coumaric acid and luminol were procured from Sigma-Aldrich (St. Louis, MO). Glycerylmonooleate (GMO) was purchased from Eastman (Memphis, TN). Sodium chloride was procured from MP biomedical (Cedex, France). Acetonitrile and methanol were obtained from Spectrochem, Pvt. Ltd. (Mumbai, India). Dimethyl sulphoxide, ammonium acetate and acetic acid were obtained from Merck, India Pvt. Ltd. (Mumbai, India). Tris base was purchased from Promega (Promega Corporation, Madison, Wisconsin). All other chemicals used were purchased from Sigma-Aldrich (St. Louis, MO) and used without further purification.
D α tocopherol polyethylene glycol 1000 succinate
Manufactured by Merck Group
Sourced in United States, France
D-α-Tocopherol polyethylene glycol 1000 succinate is a water-soluble derivative of vitamin E. It is used as a surfactant and emulsifier in various laboratory and pharmaceutical applications.
Automatically generated - may contain errors
Lab products found in correlation
Curcumin, by Merck Group (3 mentions)
Rhodamine 123, by Merck Group (2 mentions)
Ethanol, by Merck Group (2 mentions)
Pluronic f 68 pf68, by Merck Group (2 mentions)
Coumarin 6, by Merck Group (2 mentions)
Sodium dodecyl sulphate (sds), by Merck Group (1 mentions)
Crystal violet, by Merck Group (1 mentions)
Tris base, by Promega (1 mentions)
Brilliant blue g, by Merck Group (1 mentions)
Berbamine, by Merck Group (1 mentions)
Sodium chloride (nacl), by MP Biomedicals (1 mentions)
3 4 5 dimethylthiazol 2 yl 2 5 diphenyltetrazolium bromide, by Merck Group (1 mentions)
Mitomycin c, by Merck Group (1 mentions)
Luminol, by Merck Group (1 mentions)
Gelatin, by Merck Group (1 mentions)
Propidium iodide, by Merck Group (1 mentions)
Protease inhibitor cocktail, by Merck Group (1 mentions)
Pluronic f 127, by Merck Group (1 mentions)
Triethylamine, by Merck Group (1 mentions)
Bradford reagent, by Merck Group (1 mentions)
17 protocols using d α tocopherol polyethylene glycol 1000 succinate
1
Berbamine-based Nanomedicine Formulation
2
Formulation of Lipid-Based Nanocarriers
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Polyhexamethylene biguanide (PHMB) was purchased from Lonza, UK. Retinol, curcumin, D-α-Tocopherol polyethylene glycol 1000 succinate (TPGS), polysorbate 40, and ethanol were purchased from Sigma-Aldrich (Gillingham, UK). Table 1 shows the initial ‘stock’ solutions of the compounds with the corresponding solvents and concentrations. Figure 1 shows the structure of the candidate compounds. With TPGS, two different types of stock solutions were prepared; one was obtained by simple mixing of TPGS with Milli-Q water, and the other was prepared using high-speed (5000 rpm) homogenization, enabling the formation of TPGS micelles (TPGS-M).
3
Curcumin Loaded Nanoparticle Formulation
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Curcumin (CUR), casein (CAS), sucrose (SUC), and D-α-tocopherol polyethylene glycol-1000 succinate (TPGS) were purchased from Sigma-Aldrich (Singapore). Ethanol was purchased from E. Merck (Singapore).
4
Formulation and Characterization of Elosulfase Alfa Delivery Systems
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Elosulfase alfa (Vimizim®) was provided by Biomarin (San Francisco, CA, USA). Block copolymers (Kolliphor® P407 and Kolliphor P188) and d -α-tocopherol polyethylene glycol 1000 succinate were purchased from Sigma Aldrich (St. Louis, MO, USA). Glyceril dibehenate (Compritol 888 ATO) was obtained from Gatefossé (Lyon, France). Trimyristin (Dynasan 114) and triestearin (Dynasan 118) was purchased from IOI Oleo GmbH (Hamburg, Germany). Cholesterol lanolin was obtained from Fluka (Munich, Germany), while olive oil, soy lecitin, and caprylic/capric triglyceride (Miglyol 812N) were obtained from Acofarma (Barcelona, Spain). The water used was ultrapure (milli-Q) and all other chemicals were of analytical grade.
5
Nanoparticle Formulation Development
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Polyethylene glycol (PEG 1500), stannous 2-ethylhexanoate, dexamethasone phosphate, idebenone and D-α-Tocopherol polyethylene glycol 1000 succinate (TPGS) and ketorolac tris salt were purchased from Sigma-Aldrich (Leinster, Ireland). DL-Lactide and glycolide were purchased from Corbion® (Gorinchem, The Netherlands). The dialysis membranes (Spectra-Por® Float-A-Lyzer® G2, 5 mL, MWCO 3.5–5 KDa) were from Sigma-Aldrich (Madrid, Spain). DMEM/F12 (Dulbecco’s Modified Eagle Medium/Nutrient Mixture F-12), Hank’s Balanced Salt Solution, H2O2 50% and MTT were purchased from Sigma-Aldrich (Leinster, Ireland). FBS, L-glutamine and sodium bicarbonate were purchased from Invitrogen (Dublin, Ireland). TNF and IL1b kit for inflammation studies were purchased from Invitrogen (Dublin, Ireland).
6
Gefitinib Nanoparticle Formulation
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Gefitinib (GEF) was purchased from Beijing Mesochem Technology Co. Ltd. (Beijing, China). Pluronic-F68 (PF-68) and D-α-Tocopherol polyethylene glycol 1000 succinate (TPGS) were purchased from Sigma Aldrich, St. Louis, MO, USA. Stearic acid (SA) was purchased from BDH, Poole, UK. Oleic acid (OA) was obtained from Avonchem, Cheshire, UK.
7
Epicatechin Nanoformulation for Bioavailability
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(−)-Epicatechin (≥90% purity), chitosan of 90% purity (medium molecular weight, MW 190–310 (75% deacetylation), tocopherol, d -α-tocopherol polyethylene glycol 1000 succinate (TPGS), methanol, ethanol, acetic acid and other chemicals were purchased from Sigma Aldrich-México (Toluca, state of México). Egg lecithin (Emulmetik 930TM) was obtained from Silanes Pharmaceutical Co. (Polanco, Mexico City).
8
Formulation and Characterization of Lipid Nanocarriers
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Chrysin, poloxamer 407 (Pluronic® F-127), D-α-Tocopherol polyethylene glycol 1000 succinate (TPGS), polyoxyethylene (4) lauryl ether ( Brij®L4 (formerly Brij 30)) and 3-aminopropyltriethoxysaline (ATPES, 99%) were purchased from Sigma-Aldrich Co. (St. Louis, MO, USA). Macrogol 15 Hydroxystearate (Kolliphor® HS 15) was obtained from BASF (Ludwigshafen, Germany). Magnesium chloride hexahydrate (98.0%) and other inorganic salts were supplied by Junsei Chemical Co., Ltd. (Tokyo, Japan). Dulbecco’s modified Eagle’s medium (DMEM), fetal bovine serum (FBS), and all other reagents used in cell culture studies were obtained from GE Healthcare Life Sciences (South Logan, UT, USA). All other chemicals were of analytical grade and all solvents were of HPLC grade.
9
Gefitinib and Azacitidine Formulation
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Gefitinib was purchased from Beijing Mesochem Technology Co., Ltd. (Beijing, China). Azacitidine was kindly obtained from Sudairpharma Company (Riyadh, Saudi Arabia). Poloxamer-188 (P-188) and D-α-Tocopherol polyethylene glycol 1000 succinate (TPGS) were purchased from Sigma Aldrich, St. Louis, MO, USA. Stearic acid (SA) was purchased from BDH (Poole, UK). All other chemicals and reagents were of pharmaceutical or analytical grade.
10
Development and Characterization of RBG-Loaded PLGA Nanoparticles
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RBG was purchased from Shanghai source leaf Biological Technology Co., Ltd. (Shanghai, China). P188 (MW: 8400), PLGA (50:50, MW: 40 kD), D-α-galactose (Gal), coumarin-6 (C6, purity 99%), D-α-tocopherol polyethylene glycol 1000 succinate (TPGS), sodium dodecyl sulfate (SDS, purity 99%), succinic anhydride, sulphonethane, dicyclohexylcarbodiimide (DCC), 4-dimethylaminopyridine (DMAP), DEN, tetrahydrofuran (THF), and polyethylene glycol 400 (PEG400) were purchased from Sigma-Aldrich (St. Louis, MO). Methanol and acetic acid were obtained from Tedia Company (HPLC grade, Fairfleld, OH). The 4-[3-(4-iodophenyl)-2-(4-nitrophenyl)-2H-5-tetrazolio]-1,3-benzene-sulfonate (WST-1) was obtained from Roche Applied Science (Basel, Switzerland). The 4,6-diamidino-2-phenylindole dihydrochloride (DAPI) was purchased from Fluka (Buche, Switzerland). All other chemicals and reagents of the highest quality were commercially available. HepG2 cells were offered by Chinese Academy of Medical Sciences Cell Center.
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