Nicotine (Merck Schuchardt OHG, Hohenbrunn, Germany), acetylcholine chloride, hemin, Nw-nitro-L-arginine methylester hydrochloride (L-NAME), L-arginine hydrochloride, papaverine hydrochloride, mifepristone, phenylephrine hydrochloride, N-ethylcarboxamidoadenosine, 17β-estradiol, zinc protoporphyrin IX (ZnPP, Sigma Chemical Co., St. Louis, MO, U.S.A.), medroxyprogesterone acetate (Pfizer, New York, U.S.A.), thiopental sodium (Thiopental, Biochemie GmbH, Vienna, Austria) were purchased from commercial vendors.
Nw nitro l arginine methylester hydrochloride l name
Manufactured by Merck Group
Sourced in Germany, United States
Nw-nitro-L-arginine methylester hydrochloride (L-NAME) is a chemical compound used as a research tool. It functions as a nitric oxide synthase inhibitor.
Automatically generated - may contain errors
Lab products found in correlation
17β estradiol, by Merck Group (1 mentions)
Hemin, by Merck Group (1 mentions)
Mifepristone, by Merck Group (1 mentions)
Phenylephrine hydrochloride, by Merck Group (1 mentions)
Medroxyprogesterone acetate, by Pfizer (1 mentions)
Nicotine, by Merck Group (1 mentions)
Acetylcholine chloride, by Merck Group (1 mentions)
Papaverine hydrochloride, by Merck Group (1 mentions)
Zinc protoporphyrin 9 znpp, by Merck Group (1 mentions)
L arginine hydrochloride, by Merck Group (1 mentions)
Parecoxib, by Pfizer (1 mentions)
Piroxicam, by Pfizer (1 mentions)
N n dimethylformamide (dmf), by Merck Group (1 mentions)
Cremophor el, by Merck Group (1 mentions)
U46619, by Cayman Chemical (1 mentions)
Sr59230a, by Merck Group (1 mentions)
Cyclodextran, by Merck Group (1 mentions)
Brl 37344, by Bio-Techne (1 mentions)
3 protocols using nw nitro l arginine methylester hydrochloride l name
1
Pharmacological Modulators of Vascular Function
2
Drug Administration Protocol
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The drugs were freshly dissolved in a physiological salt solution of 10 mg/kg for i.p. administration. Piroxicam was provided by Pfizer Chile, parecoxib by Pfizer Chile, ketoprofen by Rhone Poulenc Rorer, dexketoprofen was a gift from Menarini Laboratories, Spain. N w nitroLarginine methyl ester hydrochloride (LNAME) and 7nitroindazol,were purchased from SigmaAldrich Chemical Co, St. Louis, MO, USA.
3
Pharmacological Agents for Hemodynamic Studies
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Nebivolol (Forest Research Institute, Jersey City, NJ) and BRL 37344 (Tocris Biosciences, Minneapolis, MN) were dissolved in a 15% cyclodextran (Sigma-Aldrich, St. Louis, MO) solution in 0.9% saline. Dobutamine hydrochloride (Cayman Chemical, Ann Arbor, MI), N-w-Nitro-L-Arginine Methyl Ester hydrochloride (L-NAME), and SR59230A (Sigma-Aldrich, St. Louis, MO) were dissolved in 0.9% NaCl.
Monocrotaline hydrochloride (Sigma Aldrich, St. Louis, MO) was dissolved in 1 N HCl, neutralized with 0.5N NaOH, and diluted with PBS. The filtered solution was then injected into the tail vein in a dose of 60 mg/kg. U46619 (Cayman Chemical, Ann Arbor, D r a f t 9 MI) was dissolved in 95% ethyl alcohol and diluted in 0.9% NaCl solution. Mirabegron (Astellas Pharm US, Northbrook, IL) was dissolved in 70% 0.9% NaCl, 15% Cremophor EL (Sigma Aldrich, St. Louis, MO), and 15% N,N-dimethylformamide (Sigma Aldrich, St.
Monocrotaline hydrochloride (Sigma Aldrich, St. Louis, MO) was dissolved in 1 N HCl, neutralized with 0.5N NaOH, and diluted with PBS. The filtered solution was then injected into the tail vein in a dose of 60 mg/kg. U46619 (Cayman Chemical, Ann Arbor, D r a f t 9 MI) was dissolved in 95% ethyl alcohol and diluted in 0.9% NaCl solution. Mirabegron (Astellas Pharm US, Northbrook, IL) was dissolved in 70% 0.9% NaCl, 15% Cremophor EL (Sigma Aldrich, St. Louis, MO), and 15% N,N-dimethylformamide (Sigma Aldrich, St.
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