LCMS analysis was performed on an Agilent 6530 series Q-TOF LC/MS spectrometer. A Waters ACQUITY UPLC BEH C18, 1.7 μm, 2.1 × 100 nm column was used as the stationary phase. Aqueous phase was Buffer A (950 mL water, 25 mL methanol, 26 mL hexafluoro-2-propanol (HFIP) and 2.5 mL triethyl amine) and organic phase was Buffer B (925 mL methanol, 50 mL water, 26 mL hexafluoro-2-propanol (HFIP) and 2.5 mL triethyl amine). The gradient was 0–100% of Buffer B for 30 min followed by 100% Buffer B for 5 min at a flow rate of 0.2 mL/min and a set temperature of 25°C. The observed masses of the ASOs were consistent with the expected theoretical masses.
6530 series q tof lc ms spectrometer
Manufactured by Agilent Technologies
The 6530 series Q-TOF LC/MS spectrometer is a high-resolution mass spectrometry instrument that combines liquid chromatography (LC) with quadrupole time-of-flight (Q-TOF) mass analysis. It is designed to provide accurate mass measurements and detailed structural information for a wide range of chemical compounds.
Automatically generated - may contain errors
Lab products found in correlation
2 protocols using 6530 series q tof lc ms spectrometer
1
LCMS Analysis of Antisense Oligonucleotides
2
LCMS Analysis of Antisense Oligonucleotides
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
LCMS analysis was performed on an Agilent 6530 series Q-TOF LC/MS spectrometer. A Waters ACQUITY UPLC BEH C18, 1.7 μm, 2.1 × 100 nm column was used as the stationary phase. Aqueous phase was Buffer A (950 mL water, 25 mL methanol, 26 mL hexafluoro-2-propanol (HFIP) and 2.5 mL triethyl amine) and organic phase was Buffer B (925 mL methanol, 50 mL water, 26 mL hexafluoro-2-propanol (HFIP) and 2.5 mL triethyl amine). The gradient was 0–100% of Buffer B for 30 min followed by 100% Buffer B for 5 min at a flow rate of 0.2 mL/min and a set temperature of 25°C. The observed masses of the ASOs were consistent with the expected theoretical masses.
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!