Tropicol

Manufactured by Bioptigen

Tropicol is a laboratory equipment designed for optical coherence tomography (OCT) imaging. It provides high-resolution, three-dimensional visualization of biological samples. The core function of Tropicol is to capture and process OCT data, enabling detailed analysis of tissue structures and morphology.

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Lab products found in correlation

Envisu r2200, by Bioptigen (2 mentions) Invivovue diver, by Bioptigen (1 mentions) Invivovue diver 3, by Bioptigen (1 mentions)

2 protocols using tropicol

Retinal Layer Thickness Imaging Protocol

Cited 1 time

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Optical coherence tomography imaging was performed as described before (Sergeys et al., 2019 (link); Vandenabeele et al., 2021 (link)). Briefly, after pupil dilatation with tropicamide (0.5%, Tropicol, Théa), the retina of anesthetized animals was imaged (1000 A-scans, 100 B-scans, 1.4 × 1.4 mm, Bioptigen Envisu R2200). Retinal layer thickness was measured using InVivoVue Diver (v 3.0.8, Bioptigen) software, at 16 locations in the central retina spaced around the optic nerve head, and averaged per mouse.

Veys L., Devroye J., Lefevere E., Cools L., Vandenabeele M, & De Groef L. (2021). Characterizing the Retinal Phenotype of the Thy1-h[A30P]α-syn Mouse Model of Parkinson’s Disease. Frontiers in Neuroscience, 15, 726476.

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Retinal Layer Thickness Measurement

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Upon general anesthesia and pupil dilatation (0.5% tropicamide, Tropicol, Théa), optical coherence tomography scans of the retina (1000 A-scans, 100 B-scans, 1.4 × 1.4 mm, Bioptigen Envisu R2200) were acquired. Retinal layer thickness was measured using InVivoVue Diver 3.0.8 software (Bioptigen), at 16 locations equally spaced around the optic nerve head and averaged per mouse.

Vandenabeele M., Veys L., Lemmens S., Hadoux X., Gelders G., Masin L., Serneels L., Theunis J., Saito T., Saido T.C., Jayapala M., De Boever P., De Strooper B., Stalmans I., van Wijngaarden P., Moons L, & De Groef L. (2021). The AppNL-G-F mouse retina is a site for preclinical Alzheimer’s disease diagnosis and research. Acta Neuropathologica Communications, 9, 6.

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