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M80 scope

Manufactured by Leica camera
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The M80 scope is a high-quality optical instrument designed for laboratory use. It features a magnification range of 8x to 80x, allowing for detailed inspection and analysis of various specimens. The M80 scope is equipped with a sturdy, ergonomic design and delivers clear, high-resolution images to support precision-oriented tasks.

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Lab products found in correlation

Tricaine, by Thermo Fisher Scientific (2 mentions) Ic80 hd camera, by Leica camera (2 mentions) Nosepiece attachment, by Leica camera (2 mentions)

2 protocols using m80 scope

1

Zebrafish Heart Rate Monitoring

Check if the same lab product or an alternative is used in the 5 most similar protocols
Zebrafish express Zerg, an orthologue of hERG, and many hERG inhibitors induce bradycardia an arrhythmia in zebrafish.35 (link) Heart rate was recorded and calculated as reported previously36 (link) with slight modifications (n = 3–9). Briefly, 7 dpf zebrafish larvae were anesthetized with tricaine (Acros Organics) and immobilized in a lateral orientation using 1% low melt agarose (LMA, Gene Mate) dissolved in egg water.37 tricaine was washed out and drug was added to 4 mL embryo media in a 6-well plate (final concentration = 50 μM). Videos were collected at 30 frames per second (fps) using a Leica M80 scope with an ACHRO 1x nosepiece attachment and a Leica IC80 HD camera. Regions of interest (ROIs) were drawn around the atrium and ventricle of individual zebrafish and average pixel dynamics were calculated using the ImageJ plugin Time Series Analyzer V3. This pixel change oscillation was graphically smoothed using the Savgol filter in SciPy. Peaks were detected using the SciPy package “find_peaks”. Peak time interval and BPM were calculated using custom code. The arrythmia score was calculated as the ratio of atrium BPM to ventricle BPM (n = 6–18).
Cameron L.P., Tombari R.J., Lu J., Pell A.J., Hurley Z.Q., Ehinger Y., Vargas M.V., McCarroll M.N., Taylor J.C., Myers-Turnbull D., Liu T., Yaghoobi B., Laskowski L.J., Anderson E.I., Zhang G., Viswanathan J., Brown B.M., Tjia M., Dunlap L.E., Rabow Z.T., Fiehn O., Wulff H., McCorvy J.D., Lein P.J., Kokel D., Ron D., Peters J., Zuo Y, & Olson D.E. (2020). A Non-Hallucinogenic Psychedelic Analog with Therapeutic Potential. Nature, 589(7842), 474-479.
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2

Zebrafish Heart Rate Monitoring

Check if the same lab product or an alternative is used in the 5 most similar protocols
Zebrafish express Zerg, an orthologue of hERG, and many hERG inhibitors induce bradycardia an arrhythmia in zebrafish.35 (link) Heart rate was recorded and calculated as reported previously36 (link) with slight modifications (n = 3–9). Briefly, 7 dpf zebrafish larvae were anesthetized with tricaine (Acros Organics) and immobilized in a lateral orientation using 1% low melt agarose (LMA, Gene Mate) dissolved in egg water.37 tricaine was washed out and drug was added to 4 mL embryo media in a 6-well plate (final concentration = 50 μM). Videos were collected at 30 frames per second (fps) using a Leica M80 scope with an ACHRO 1x nosepiece attachment and a Leica IC80 HD camera. Regions of interest (ROIs) were drawn around the atrium and ventricle of individual zebrafish and average pixel dynamics were calculated using the ImageJ plugin Time Series Analyzer V3. This pixel change oscillation was graphically smoothed using the Savgol filter in SciPy. Peaks were detected using the SciPy package “find_peaks”. Peak time interval and BPM were calculated using custom code. The arrythmia score was calculated as the ratio of atrium BPM to ventricle BPM (n = 6–18).
Cameron L.P., Tombari R.J., Lu J., Pell A.J., Hurley Z.Q., Ehinger Y., Vargas M.V., McCarroll M.N., Taylor J.C., Myers-Turnbull D., Liu T., Yaghoobi B., Laskowski L.J., Anderson E.I., Zhang G., Viswanathan J., Brown B.M., Tjia M., Dunlap L.E., Rabow Z.T., Fiehn O., Wulff H., McCorvy J.D., Lein P.J., Kokel D., Ron D., Peters J., Zuo Y, & Olson D.E. (2020). A Non-Hallucinogenic Psychedelic Analog with Therapeutic Potential. Nature, 589(7842), 474-479.
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