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Mca2260

Manufactured by Bio-Rad
Sourced in United States

The MCA2260 is a laboratory instrument designed for electrophoresis applications. It provides a consistent and reliable platform for the separation and analysis of biomolecules such as proteins, nucleic acids, and other macromolecules. The MCA2260 features a durable construction and precise temperature control to ensure accurate and reproducible results.

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2 protocols using mca2260

1

Xenograft Mouse Model for Rituximab

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All chemicals and proteins were purchased from Sigma-Aldrich (St. Louis, Missouri, USA) unless otherwise noted. All cell culture reagents were purchased from ThermoFisher Scientific (Waltham, Massachusetts, USA) unless otherwise noted. Hydrolysable crosslinker poly(DL-lactide)-b-poly(ethylene glycol)-b-poly(DL-lactide)-diacrylate triblock (PLA–PEG–PLA) was purchased from PolySciTech Akina (West Lafeyette, Indiana, USA). Capture antibody for ELISA against RTX was purchased from Bio-Rad Laboratories (MCA2260, Hercules, California, USA). HRP-conjugated goat antihuman IgG Fc for ELISA assay was purchased from ThermoFisher Scientific. antihuman CD45, antihuman CD3, antihuman CD56, antihuman CD11b, antihuman CD14, antihuman CD4, and antihuman CD8 were purchased from BioLegend (San Diego, California, USA). RTX (RITUXANTM: Genentech, San Francisco, California, USA) and HER (Herceptin: Genentech) were obtained at the UCLA hospital pharmacy. All NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG) and NOD.Cg−Hc1Prkdcscid Il2rgtm1Wjl/SzJ (NSG−Hc1) mice were purchased from The Jackson Laboratory and housed in specific pathogen-free vivarium.
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2

Odronextamab and Anti-Idiotype Antibodies

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Odronextamab (REGN1979), anti-idiotype antibodies specific for CD20-or CD3-binding arms of the bispecific drug, and isotype controls were produced by Regeneron Pharmaceuticals, Inc (Tarrytown, New York). Rituxan® (rituximab) is manufactured by Genentech (San Francisco, CA). Anti-rituximab blocking antibodies HCA061, HCA186, and MCA2260 were purchased from Bio-Rad (Hercules, California).
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