Isorhapontigenin

Piceatannol (>98.0%), resveratrol (>99.0%), rhapontigenin (>98.0%), isorhapontigenin (>96.0%), piceid (>95.0%), pinostilbene (>97.0%), caffeic acid (>98.0%), and p-coumaric acid (>98.0%) were obtained from Tokyo Chemical Industry (Tokyo, Japan). Gnetin C (>97.0%), and special grade ethanol (>99.5%) were obtained from FUJIFILM Wako Pure Chemical Corporation (Osaka, Japan). Astringin was obtained from Sequoia Research Products limited company (Pangbourne, United Kingdom). Epicatechin (>90.0%) was obtained from Sigma-Aldrich Japan (Tokyo, Japan). LC-MS grade acetonitrile (>99.9%), LC-MS grade distilled water, and HPLC grade formic acid (>98.0%) were obtained from Kanto Chemical Co., Inc. (Tokyo, Japan).

PIC, RES, oxyresveratrol (OXY), rhapontigenin (RHA), isorhapontigenin (ISOR), 3,3′,4,5′-tetramethoxypiceatannol (TMP), and sesamin (SESA) were obtained from Tokyo Chemical Industry Co., Ltd. (Tokyo, Japan). Dimethyl sulfoxide (DMSO), EGCG, H₂O₂, and N-acetylcysteine (NAC) were obtained from Wako Pure Chemical Industries, Ltd. (Osaka, Japan). QUE was obtained from Tocric Co., Ltd. (Bristol, UK). Dulbecco's modified Eagle's medium (DMEM), heat-inactivated horse serum (HS), Hanks' Balanced Salt solution (HBSS), and penicillin and streptomycin solutions were obtained from Gibco (MD, USA). Fetal bovine serum (FBS) was obtained from HyClone (UT, USA). The 5-(and-6) chloromethyl-2′,7′ dichlorodihydrofluorescein diacetate, acetyl ester (CM-H₂DCFDA) was obtained from Invitrogen (CA, USA).