Two electrophysiologists (MS and JvO) with extensive experience in cryoballoon ablation performed the procedures. All patients were on oral vitamin-K antagonists with the international normalised ratio between 2.5 and 3.5. Vitamin K antagonists were continued during the procedure [14 ]. All procedures were performed under general anaesthesia and arterial blood pressure was continuously monitored. Venous access was obtained from the right and left femoral vein. A diagnostic catheter (EP XT CS 4p, BARD Medical Inc., GA, USA) was positioned in the coronary sinus for stimulation of the LA. The LA was accessed by a transseptal puncture with a Brockenbrough needle monitored by intracardiac echocardiography (St. Jude Medical, MN, USA), first with a SL-O sheath (St. Jude Medical, MN, USA), changed over a 0.32 F wire to a steerable 12 F sheath (Flexcath, Medtronic Inc., MN, USA). During the procedure, heparin was given to achieve an activated clotting time of >350 s. The use of a 23 or 28 mm balloon was based on the PV diameters.
Brockenbrough needle
Manufactured by Abbott
Sourced in United States
The Brockenbrough needle is a medical device used for obtaining tissue samples or performing fine-needle aspiration biopsies. It is a hollow, thin, and rigid needle designed to extract small amounts of tissue or fluid from a specific location in the body for diagnostic purposes.
Automatically generated - may contain errors
Lab products found in correlation
Flexcath, by Medtronic (1 mentions)
Inquiry optima, by Abbott (1 mentions)
Blazer, by Boston Scientific (1 mentions)
Ensite velocity, by Abbott (1 mentions)
Thermocool, by Johnson & Johnson (1 mentions)
Rhythmia mapping system, by Boston Scientific (1 mentions)
Tacticath, by Abbott (1 mentions)
Thermocool smarttouch, by Johnson & Johnson (1 mentions)
Carto 3 system, by Johnson & Johnson (1 mentions)
Pentaray, by Johnson & Johnson (1 mentions)
Intellamap orion, by Boston Scientific (1 mentions)
Flexcath advance, by Medtronic (1 mentions)
4 protocols using brockenbrough needle
1
Cryoballoon Ablation Procedure for Atrial Fibrillation
2
In vivo LA access in healthy pigs
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
In vivo experiments were performed in the LA of 5 healthy pigs weighing 66 ± 4 kg at the Atrial Fibrillation Innovation Center (Cleveland Clinic, USA). The experiment was performed in accordance with a protocol approved by the Institutional Animal Care and Use Committee of the Cleveland Clinic and complied with the ARRIVE guidelines. Under anesthesia, the LA was accessed percutaneously by transseptal puncture (Brockenbrough needle, St. Jude Medical, USA) with the guidance of biplane fluoroscopy and intracardiac echocardiography (8-Fr AcuNav, Johnson & Johnson Medical, USA).
3
Radiofrequency Catheter Ablation for Atrial Fibrillation
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
All procedures were performed under general anesthesia. Transoesophageal echocardiography was performed preprocedurally to exclude the presence of left atrial thrombus. Vascular access was via the right and/or left femoral veins using two transseptal long sheaths (SL0, St. Jude Medical Inc., St Paul, MN, USA). Transseptal access was performed using a Brockenbrough needle (St. Jude Medical Inc.). After gaining LA access, unfractionated heparin was given to achieve an activated clotting time of greater than 300 seconds.
Mapping and ablation were performed using an electro‐anatomic mapping system (CARTO‐3 system, Biosense Webster, Diamond Bar, CA, USA; EnSite Velocity, St. Jude Medical, St Paul, MN, USA; Rhythmia mapping system, Boston Scientific, Marlborough, MA, USA). Multipolar mapping catheters were used in all cases (Lasso or PentaRay, Biosense Webster; Inquiry Optima, St. Jude Medical; IntellaMap Orion, Boston).
Ablation was performed with 3‐4 millimetre irrigated‐tip catheters (Thermocool SmartTouch or Thermocool, Biosense Webster; TactiCath or Flexability, St. Jude Medical; Blazer, Boston Scientific). Power settings of 25‐30 watts (w) were used in all areas other than for a cavotricuspid isthmus (CTI) line, where up to 40 w was used, and for a mitral isthmus line, where up to 35 w was used. No specific guidance concerning contact force settings was given.
Mapping and ablation were performed using an electro‐anatomic mapping system (CARTO‐3 system, Biosense Webster, Diamond Bar, CA, USA; EnSite Velocity, St. Jude Medical, St Paul, MN, USA; Rhythmia mapping system, Boston Scientific, Marlborough, MA, USA). Multipolar mapping catheters were used in all cases (Lasso or PentaRay, Biosense Webster; Inquiry Optima, St. Jude Medical; IntellaMap Orion, Boston).
Ablation was performed with 3‐4 millimetre irrigated‐tip catheters (Thermocool SmartTouch or Thermocool, Biosense Webster; TactiCath or Flexability, St. Jude Medical; Blazer, Boston Scientific). Power settings of 25‐30 watts (w) were used in all areas other than for a cavotricuspid isthmus (CTI) line, where up to 40 w was used, and for a mitral isthmus line, where up to 35 w was used. No specific guidance concerning contact force settings was given.
4
Cryoballoon Ablation for Atrial Fibrillation
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
All the procedures were performed under local anesthesia with mild conscious sedation. In the cryoablation group, the second-generation cryoballoon ablation catheter was used (Arctic Front Advanced, Medtronic, Minneapolis, MN, USA). The patients had a groin entry venous route catheter introduced with the transseptal puncture by means of a Brockenbrough needle (St. Jude Medical). In addition, a 15 Fr steerable sheath (FlexCath Advance, Medtronic) and an integrated inner-lumen circular mapping catheter (CMC, Achieve™; Medtronic, Inc.) were applied9 (link). The cryoballoon was introduced into the target PV, and its position was confirmed by contrast retention. The freezing cycles, lasting 180–240 s, were performed for each PV and were confirmed by the Achieve catheter9 (link). In the absence of PV potentials, the procedure was ended; otherwise, next cryoapplications were performed. During the application in the right veins, the diphragmatic nerve was constantly stimulated (30/min) to avoid its paralysis. Freezing was immediately terminated at any indication of diaphragmatic weakness or palsy.
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!