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Gastric pepsin

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Gastric pepsin is a digestive enzyme that is produced in the stomach. It plays a key role in the breakdown of proteins during the digestive process.

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Pepsin (34 citations) Pepsin from porcine gastric mucosa (2 citations)

2 protocols using gastric pepsin

1

Trichinella spiralis Infection Model

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Infection with Trichinella spiralis (Lanzhou Veterinary Research Institute, Lanzhou, China) was performed to establish the PI-IBS model[28 (link)]. After 60 d of infection, the parasite larvae were digested from Sprague–Dawley rats with 1.5% gastric pepsin (Invitrogen, Carlsbad, CA, United States) and suspended in 0.2 mL of saline. The mice were fed the larvae (300 larvae/mouse).
Dong L.W., Ma Z.C., Fu J., Huang B.L., Liu F.J., Sun D, & Lan C. (2022). Upregulated adenosine 2A receptor accelerates post-infectious irritable bowel syndrome by promoting CD4+ T cells’ T helper 17 polarization. World Journal of Gastroenterology, 28(25), 2955-2967.
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2

Trichinella spiralis Infection in Mice

Cited 1 time
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The mice were infected with T. spiralis (Lanzhou Animal Medical Institute, Lanzhou, China) as described previously [18 (link)]. Briefly, the parasite larvae were separated from Sprague–Dawley rats 60 days after infection of T. spiralis’ cyst by digestion with 1.5% gastric pepsin (Invitrogen Co., CA, USA). The mice were fed with the larvae in 0.2 ml saline (300 larvae per mouse). The animals in the control group were fed with only 0.9% saline.
He Z., Sun X., Ma Z., Fu J., Huang B., Liu F., Chen Y., Deng T., Han X., Sun D, & Lan C. (2018). Heat shock protein 70 protects mouse against post-infection irritable bowel syndrome via up-regulating intestinal γδ T cell’s Th17 response. Cell & Bioscience, 8, 38.
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