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Pluronic l64

Manufactured by BASF
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Sourced in Germany, Japan

Pluronic L64 is a nonionic triblock copolymer surfactant. It is composed of a central hydrophobic block of polypropylene oxide (PPO) flanked by two hydrophilic blocks of polyethylene oxide (PEO). Pluronic L64 is a common laboratory reagent used for its emulsifying, dispersing, and solubilizing properties.

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Lab products found in correlation

Coumarin 6, by Merck Group (1 mentions) 3 4 5 dimethylthiazol 2 yl 2 5 diphenyltetrazolium bromide mtt, by Merck Group (1 mentions) Dimethyl sulfoxide (dmso), by Merck Group (1 mentions) Ethanol, by Avantor (1 mentions) Propylene glycol, by Merck Group (1 mentions) Acetonitrile, by Avantor (1 mentions) N hexane, by Avantor (1 mentions) Tetraglycol, by Merck Group (1 mentions) Cremophor el, by BASF (1 mentions) Tween 80, by Samchun (1 mentions) Microflex lrf maldi tof, by Bruker (1 mentions) Ltq orbitrap xl, by Thermo Fisher Scientific (1 mentions) Rabbit serum, by Solarbio (1 mentions) Pluronic f127, by BASF (1 mentions)

2 protocols using pluronic l64

1

Solubilization and Characterization of DTX

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DTX was provided by Korea United Pharma Inc. (Seoul, Korea). Lauroglycol 90, Lauroglycol FCC, Labrafac Lipophile WL 1349, Labrafac CC, Capryol 90, Labrafil M 1944 CS, Transcutol P, and Labrasol were obtained from Gattefossé Co. (Lyon, France). Capmul MCM was purchased from the Abitec Corporation (Cleveland, OH, USA). Polyethylene glycol 400 (PEG 400), Tween 20, and Tween 80 were bought from Samchun Chemical Co., Ltd (Pyungtaek, Korea). Cremophor EL and Pluronic L64 were provided by BASF Co. (Ludwigshafen, Germany). Tetraglycol, propylene glycol, dimethyl sulfoxide (DMSO), Coumarin-6 (C6), and 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Lipoid® S100 (phospholipid, PLC) was obtained from Lipoid Co. (Ludwigshafen, Germany). The high-performance liquid chromatography (HPLC) grade methanol, acetonitrile, n-hexane, and ethanol were bought from J.T. Baker (Phillipsburg, NJ, USA).
Wang M., You S.K., Lee H.K., Han M.G., Lee H.M., Pham T.M., Na Y.G, & Cho C.W. (2020). Development and Evaluation of Docetaxel-Phospholipid Complex Loaded Self-Microemulsifying Drug Delivery System: Optimization and In Vitro/Ex Vivo Studies. Pharmaceutics, 12(6), 544.
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2

Pluronic-Mediated Hepcidin Peptide Analysis

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Pluronic L121 (PEO5-PPO70-PEO5), Pluronic L64 (PEO13-PPO30-PEO13) and Pluronic F127 (PEO106-PPO70-PEO106) are gift from BASF Co.. All the other chemicals utilized in the study were purchased from Sigma-Aldrich Co.. Synthetic human hepcidin was obtained from Peptides Institute Inc. (Osaka, Japan). Rabbit serum was obtained from Solarbio Science & Technology Co. (Beijing, China). Peptide analysis was carried out using a Bruker Daltonics’ MicroflexTM LRF MALDI-TOF (Billerica, MA, USA). LC-MS/MS was performed using HPLC (Agilent 1200 series) and LTQ-Orbitrap XL (Thermo, San Jose, CA).
Fan J., Niu S., Dong A., Shi J., Wu H.J., Fine D.H., Tian Y., Zhou C., Liu X., Sun T., Anderson G.J., Ferrari M., Nie G., Hu Y, & Zhao Y. (2014). Nanopore film based enrichment and quantification of low abundance hepcidin from human bodily fluids. Nanomedicine : nanotechnology, biology, and medicine, 10(5), 879-888.
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