We considered 842 Parkinson’s disease cases from the Oxford Discovery cohort [4 (link), 6 (link)]. Individuals were required to have at least 90% chance of Parkinson’s disease according to UK-Parkinson’s disease brain bank criteria, no alternative diagnosis and disease duration less than 3.5 years. All patients had a clinical assessment repeated every eighteen months and have been already described [4 (link), 6 (link)]. Phenotype data were collected for over a hundred clinical attributes, affecting autonomic, neurological and motor phenotypes (Additional file 1 : Fig S1) and described in the Additional file 2 : Table S1. Genotype data were generated using the Illumina HumanCoreExome-12 v1.1 and Illumina InfiniumCoreExome-24 v1.1 SNP arrays. To access to the clinical data of the Oxford Discovery cohort [4 (link), 6 (link)], researchers must apply to the Oxford Parkinson’s Disease Centre (OPDC).
Infinium coreexome 24 v1
Manufactured by Illumina
Sourced in Australia
The Infinium CoreExome-24 v1.1 is a high-throughput genotyping array designed by Illumina. It provides comprehensive coverage of genetic variation across the human genome, including content from the Infinium Exome-24 v1.1 BeadChip, which interrogates over 240,000 genetic markers.
Automatically generated - may contain errors
Lab products found in correlation
4 protocols using infinium coreexome 24 v1
1
Parkinson's Disease Cohort Analysis
2
Copy Number Variation Analysis of iPSCs
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
Copy number variation analysis of isogenic iPSCs was performed using Illumina Infinium CoreExome-24 v1.1, performed by the Victorian Clinical Genetics Services (VCGS, Melbourne, Australia).
3
Copy Number Variation Analysis of iPSCs
4
Illumina Core Exome Genotyping Cohorts
Check if the same lab product or an alternative is used in the 5 most similar protocols
+ Expand
We used Illumina HumanCoreExome-12v1-1 for genoting cohort 1 and Illumina InfiniumCoreExome-24v1-1 for genotyping cohort 2–4 patients.
About PubCompare
Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.
We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.
However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.
Ready to get started?
Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required
Revolutionizing how scientists
search and build protocols!