Skyra 3.0t

Manufactured by Siemens

Sourced in Germany, United States

The Skyra 3.0T is a magnetic resonance imaging (MRI) system produced by Siemens. It operates at a field strength of 3.0 Tesla, which allows for high-quality imaging capabilities. The core function of the Skyra 3.0T is to generate detailed images of the human body for diagnostic and clinical purposes.

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Lab products found in correlation

Magnevist, by Bayer (5 mentions) Signa hdxt mr750 3.0t, by GE Healthcare (3 mentions) Magnetom symphony 1 5t, by Siemens (3 mentions) Gadovist, by Bayer (2 mentions) Gyroscan intera 1.5t master, by Philips (2 mentions) Petra, by Siemens (1 mentions) Zoletil 50, by Virbac (1 mentions) Matlab, by MathWorks (1 mentions) Intera 1.5t, by Siemens (1 mentions) Syngo fastview software, by Siemens (1 mentions) 20 channel head neck coil, by Siemens (1 mentions) Optima mr450w, by GE Healthcare (1 mentions) Somatom definition scanner, by Siemens (1 mentions) Syngo fastview, by Siemens (1 mentions) Achieva 3.0t, by Philips (1 mentions) Signa hdxt 1.5t, by GE Healthcare (1 mentions) Optima ct660, by GE Healthcare (1 mentions) Ge discovery mr750, by Siemens (1 mentions) Discovery 750w, by GE Healthcare (1 mentions) Primovist, by Bayer (1 mentions)

Spelling variants of this product

MAGNETOM Skyra 3.0T (19 citations) SKYRA 3.0T MRI scanner (12 citations) Skyra 3.0T scanner (9 citations) Magnetom Skyra 3.0T MRI scanner (5 citations)

38 protocols using skyra 3.0t

Carotid HR-MRI Examination Protocol

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In order to perform the carotid HR-MRI examinations, the Siemens Skyra 3.0T nuclear magnetic resonance scanning system (Siemens Healthineers) was employed. The coil used was the Siemens head-and-neck combined coil. The patient was instructed to lay down on the examination bed, where the head was later tilted. Prior to the scan, the examinee was subjected to a longer scan time, where the examinees were instructed to allow their body to relax. After having adjusted themselves to a comfortable position, the patients were restricting from moving their bodies freely during the scanning process in order to minimize swallowing, to reduce artifacts during imaging and to improve image quality. In terms of HR-MRI, carotid plaque three-dimensional time-of-flight (3D-TOF) scans [time of repetition (TR), 29 msec; time of echo (TE), 4 msec; field of view (FOV), 160/180 mesc], T1W1 black blood scans (TR, 800 msec; TE, 10 msec; FOV, 160/180 msec) and T2WI black blood nuclear scans (TR, 3500 msec; TE, 60 msec; FOV, 160/180 msec) were sequentially performed on each patient. Concerning the neck positioning image scanning method, the following procedure was followed: The sagittal position was centered at the position of the 3-4 level of the flat cervical vertebra, and in the coronal and transverse positioning images, the target area was placed in the center of the field-of-view (FOV) frame.

Sun Y., Xu L., Jiang Y., Ma M., Wang X.Y, & Xing Y. (2020). Significance of high resolution MRI in the identification of carotid plaque. Experimental and Therapeutic Medicine, 20(4), 3653-3660.

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Multimodal MRI Acquisition Protocol for Neuroimaging

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All MRI data were acquired on a SIEMENS SKYRA 3.0T magnetic resonance scanner (Siemens, Germany) in the Department of Radiology at the Union Hospital, Tongji Medical College, Huazhong University. All of the subjects were instructed to avoid caffeine or other similar substances before examination. They were kept in the supine position and asked to relax without falling asleep and to keep their eyes closed during scanning. Earplugs and a sponge pad were used to minimize scanner noise to protect the hearing and prevent head movement. Functional images were acquired with a single-shot gradient-recalled echo planar imaging sequence using the following parameters: time points = 240; slices = 60; slice thickness = 2.4 mm with no gaps, time of repetition (TR) = 2,000 ms; time of echo (TE) = 30 ms; flip angle (FA) = 90°; field of view (FOV) = 230 × 230 mm; and matrix size: 96 × 96; voxel size = 2.4 × 2.4 × 2.4 mm; bandwidth = 1796 Hz/Px, time = 8:13; parallel acquisition technique GRAPPA acceleration factor 2. We used a T1-weighted magnetization prepared rapid gradient echo (MP2RAGE) sequence, the following parameters: slices=176, slice thickness=1.0 mm with no gaps, TR = 5,000 ms; TE = 2.98 ms; FA = 9°, FOV = 256 × 240 mm, voxel size = 1 × 1 × 1 mm; bandwidth = 240 Hz/Px, time = 8:22parallel acquisition technique GRAPPA acceleration factor 3.

Huang M., Li X., Fan W., Li J., Zhu L., Lei P., Wu L., Sun Q., Zou Y, & Han P. (2022). Alterations of Regional Homogeneity in Crohn's Disease With Psychological Disorders: A Resting-State fMRI Study. Frontiers in Neurology, 13, 817556.

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MRI Imaging Protocol for MRONJ Assessment

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AllMRexaminationswereperformedona3TMRunitofthelatest generation (Siemens Skyra 3.0 T; Siemens Healthineers, Erlangen, Germany) using a 64-channel head coil (dto.) and the clinical standard protocol for MRONJ assessment (including an axial T1-weighted turbo spin echo; a coronal T1-weighted turbo spin echo; an axial fat-saturated, fluidsensitive turbo inversion recovery magnitude; and a diffusion-weighted MR sequence). Imaging parameters of the respective sequences are listed in Supplementary File 1, Supplemental Digital Content 1, http://links. lww.com/RLI/A480. For virtual bone imaging, a vendor-specific UTE MR sequence using pointwise encoding time reduction with radial acquisition was used ("PETRA," Siemens Healthineers), as listed in Table 1. 19

Huber F.A., Schumann P., von Spiczak J., Wurnig M.C., Klarhöfer M., Finkenstaedt T., Bedogni A, & Guggenberger R. (2020). Medication-Related Osteonecrosis of the Jaw-Comparison of Bone Imaging Using Ultrashort Echo-Time Magnetic Resonance Imaging and Cone-Beam Computed Tomography. Investigative radiology, 55(3).

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Prostate Enlargement and MRI in Beagle Dogs

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After fasting for 24 h, beagle dogs were given an intramuscular injection of sedatives (Zoletil®50, VIRBAC, France) in 10 mg/kg doses. The first Magnetic Resonance Imaging (MRI, Siemens, Skyra 3.0T) scan of the prostate was performed before the beagle dog was castrated. The subsequent MRI examinations were performed before and after every 4 weeks of the hormone treatment until the size of the prostate (Length ∗ width ∗ height ∗ 0.52) measured was larger than 18 g (Figure 1). A prostate size larger than 18 g was regarded as a measure of BPH in dogs [6 (link)].Figure 1

Flowchart of the experimental process.

Figure 1

Yuan B., Duan F., Zhang J.L., Zhang H, & Wang M.Q. (2022). Establishment of hormone-induced canine benign prostatic hyperplasia model: A prospective, controlled study. Heliyon, 8(11), e11352.

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MRI Characterization of Iron Oxide Nanoparticles

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The in vitro MRI experiment was performed under a Siemens Skyra 3.0T MRI scanner (Siemens Healthcare, Andover, MA). NPNs possessing different concentrations of Fe₃O₄ was placed in Eppendorf tubes with a diameter of 1 cm. The T₂-weighted (T₂WI) gradient-echo imaging parameters were set as follows: fast field (FFE), repetition time (TR) = 72 ms, echo time (TE) = 9 ms, flip angle = 45°, slice thickness = 3 mm, and field of view (FOV) = 180 mm. Images were displayed with a size of 256 × 256 in the matrix. We calculated the transverse relaxation rate (1/T₂) as a function of the nanoparticle volume fraction by using MatLab (The MathWorks, Inc., Natick, MA).

Tang K., Niu C., Xu Y., Zhu Y., Tang S., Zhang M, & Zhou Q. (2018). Phase-shifted paclitaxel-loaded multifunctional contrast agent for US/MR imaging and synergistic hyperthermal/chemotherapy of metastasis in lymph nodes. RSC Advances, 8(10), 5407-5419.

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Stereotactic Procedures Using ClearPoint

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ClearPoint stereotaxis was used to aid stereotactic needle biopsies, laser thermal ablations, or administration of therapeutic agents in patients undergoing clinical trial testing. Criteria for ClearPoint stereotaxis included subcentimeter contrast-enhancing lesions,⁴ (link) lesions located in the deep gray matter/brain stem,⁶ (link)^,⁷ (link) and lesions adjacent to critical anatomical structures such as the sellar⁷ (link) or periventricular regions.⁶ (link) Procedures were performed from 2015 to 2020 using 3 distinct MRIs: GE Discovery 3.0T MR 750w, Philips Intera 1.5T dedicated intraoperative MRI, and a Siemens Skyra 3.0T intraoperative MRI. Corresponding clinical information from each procedure was collected under protocols, with patient consent waived, as approved by the institutional review board. All procedures were performed by the senior author (C.C.C.).

Taha B.R., Osswald C.R., Rabon M., Garcia C.S., Guillaume D.J., Wong X., Venteicher A.S., Darrow D.P., Park M.C., McGovern R.A., Lam C.H, & Chen C.C. (2021). Learning Curve Associated with ClearPoint Neuronavigation System: A Case Series. World Neurosurgery: X, 13, 100115.

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Dynamic Contrast-Enhanced MRI of Pancreas

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All patients included in this study underwent dynamic contrast-enhanced MRI of the pancreas performed with 3.0T systems (Signa HDxt MR750 3.0T, GE Healthcare, Milwaukee, WI; Skyra 3.0T, Siemens, Erlangen, Germany). All patients were positioned supine with a phased array receiver coil covering the upper abdomen, and breath-hold single-shot fast-spin echo-coronal T₂-weighted sequence (repetition time [TR] / echo time [TE] = 6316/87 msec; field of view [FOV] = 360 × 420 mm²; matrix = 224 × 270; slice thickness = 5 mm; flip angle = 90; slice gap = 1 mm) and unenhanced and dynamic contrast-enhanced T₁-weighted fat-suppressed sequences (TR/TE = 2.58/1.18 msec; FOV = 440 × 440 mm²; matrix = 224 × 270; slice thickness = 5 mm; flip angle = 12; no slice gap) were used. Dynamic contrast-enhanced images, including arterial phase (15 sec), pancreatic parenchymal phase (20 sec), and portal venous phase (40 sec) images were obtained with gadopentetate dimeglumine (Magnevist and Gadovist, Bayer Schering Pharma, Berlin, Germany). The contrast agent was administered intravenously at a rate of 2 mL/s and a dose of 0.2 mL/kg, followed by 20 mL of normal saline (to flush the tube).

Bian Y., Zhao Z., Jiang H., Fang X., Li J., Cao K., Ma C., Guo S., Wang L., Jin G., Lu J, & Xu J. (2020). Noncontrast Radiomics Approach for Predicting Grades of Nonfunctional Pancreatic Neuroendocrine Tumors. Journal of magnetic resonance imaging : JMRI, 52(4), 1124-1136.

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Cardiac MRI Evaluation of Right Ventricular Function

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All animals underwent magnetic resonance imaging (MRI) scans 12 weeks after the surgery for the measurement of cardiac function. The animals were anesthetized and endotracheally intubated. Metoprolol solvent was slowly pushed via intravenous access until the heart rate has dropped below 180/min. The animal was then placed into the coil for positional scanning. All scans were performed using a Siemens Skyra 3.0 T magnetic resonance scanner with cardiac electrode pads attached to the chest. Scan sequences were triggered by electrocardiography (ECG) during end-expiratory pauses by using a ventilator. Cardiac MRI was performed using a steady-state free motion (SSFP) sequence. The parameters of the right ventricle scan were: TR 51.22 ms, TE 1.70 ms, flip angle 15°, layer thickness 3 mm, layer spacing 50%, the field of view 213 mm × 171.16 mm. All images were analyzed with a workstation. Right ventricular end-diastolic volumes (RV-EDV) and end-systole volumes (RV-ESV) were recorded. The right ventricular ejection fraction (RVEF) was calculated with Eq. [1 (link)].

Equation 1.

Zhao L.M., Wang L., Zhang W.Q., Wang R., Zhang X.Z., Lei X.X., Liang Y., Song Y.T., Zhang Q.Y., Lin K, & Xie H.Q. (2021). Promotion of right ventricular outflow tract reconstruction using a novel cardiac patch incorporated with hypoxia-pretreated urine-derived stem cells. Bioactive Materials, 14, 206-218.

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Neuroimaging of Anesthetized Monkey Brains

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Neuroimaging analysis was first conducted to identify gross anatomical abnormalities in the whole brains of monkeys. High-resolution images were acquired using a Siemens Skyra 3.0 T (Siemens Healthcare GMbH, Germany). Before scanning, the anesthetized monkeys were placed onto the coil bed with heads fixed. Body temperature was maintained using padding for thermal insulation. During the session, whole brain volumes were obtained, and the horizontal plane was reconstructed offline using syngo fastView software (Siemens AG, Germany).

Liu F., Wang Z.H., Huang W., Xu Y., Sang X., Liu R., Li Z.Y., Bi Y.L., Tang L., Peng J.Y., Wei J.R., Miao Z.C., Yan J.H, & Liu S. (2023). Defects and asymmetries in the visual pathway of non-human primates with natural strabismus and amblyopia. Zoological Research, 44(1), 153-168.

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Comprehensive 3T Brain MRI Protocol

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All brain MRI scans were performed using a Skyra 3.0 T equipment (Siemens) and a 20-channel head/neck coil. The MP2RAGE sequence took 5 min and 47 s [voxel size=1 mm × 1 mm × 1 mm, the field of view = 256^*240 mm, repetition time (TR) = 5,000 ms, echo time (TE) = 2.98 ms, TI1 = 700 ms, TI2 = 2,500 ms, flip angle1 = 4°, flip angle2 = 5°, 176 slices]. The MP2RAGE sequence created four sets of images automatically: INV1, INV2, UNI-Images, and T1-Images, and we used the last set of data to do quantitative measurements. No contrast was administered during the MP2RAGE sequence. T1-weighted images, T2-weighted images, T2 fluid-attenuated inversion recovery (FLAIR), and diffusion-weighted imaging (DWI) sequences were also included in the MRI protocol.

Yan H., Chen H., Liu Y., Zhang Q., Guo Y., Fu Y., Ren H., Wang H., Wang C, & Ge Y. (2022). Assessment of cognitive impairment after acute cerebral infarction with T1 relaxation time measured by MP2RAGE sequence and cerebral hemodynamic by transcranial Doppler. Frontiers in Neurology, 13, 1056423.

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