Elsd and uv detectors

Manufactured by Waters Corporation

ELSD (Evaporative Light Scattering Detector) and UV (Ultraviolet) detectors are analytical instruments used in liquid chromatography applications. The ELSD detector measures the amount of light scattered by analytes in a sample after the solvent has been evaporated, providing information about the presence and concentration of non-volatile compounds. The UV detector measures the absorbance of light by analytes at specific wavelengths, allowing the identification and quantification of compounds that absorb UV light.

Automatically generated - may contain errors

Lab products found in correlation

Bridged ethanehybrid beh c18 column, by Waters Corporation (2 mentions) Lct premier xe mass spectrometer, by Waters Corporation (2 mentions) Waters acquity uhplc system, by Waters Corporation (1 mentions)

2 protocols using elsd and uv detectors

UHPLC-MS for Compound Analysis

Check if the same lab product or an alternative is used in the 5 most similar protocols

The UHPLC was performed on a Waters
Acauity UHPLC system (Waters, Milford, MA), which was equipped with
a binary solvent delivery manager, column manager, and sample manager
coupled to ELSD and UV detectors (Waters, Milford, MA). Detection
was performed on a Waters LCT premier XE mass spectrometer (Waters,
Milford, MA). The instrument was fitted with an Acquity Bridged Ethane
Hybrid (BEH) C18 column (30 mm × 2.1 mm, 1.7 μm particle
size, Waters, Milford, MA) operated at 60 °C.

Brodney M.A., Beck E.M., Butler C.R., Barreiro G., Johnson E.F., Riddell D., Parris K., Nolan C.E., Fan Y., Atchison K., Gonzales C., Robshaw A.E., Doran S.D., Bundesmann M.W., Buzon L., Dutra J., Henegar K., LaChapelle E., Hou X., Rogers B.N., Pandit J., Lira R., Martinez-Alsina L., Mikochik P., Murray J.C., Ogilvie K., Price L., Sakya S.M., Yu A., Zhang Y, & O’Neill B.T. (2015). Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug–Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors. Journal of Medicinal Chemistry, 58(7), 3223-3252.

+ Open protocol

+ Expand

UHPLC-ELSD-MS Analysis of Compounds

Check if the same lab product or an alternative is used in the 5 most similar protocols

The UHPLC was performed on a Waters
ACQUITY UHPLC system (Waters, Milford, MA), which was equipped with
a binary solvent delivery manager, column manager, and sample manager
coupled to ELSD and UV detectors (Waters, Milford, MA). Detection
was performed on a Waters LCT premier XE mass spectrometer (Waters,
Milford, MA). The instrument was fitted with an Acquity Bridged Ethane
Hybrid (BEH) C18 column (30 mm × 2.1 mm, 1.7 μm particle
size, Waters, Milford, MA) operated at 60 °C.

Butler C.R., Ogilvie K., Martinez-Alsina L., Barreiro G., Beck E.M., Nolan C.E., Atchison K., Benvenuti E., Buzon L., Doran S., Gonzales C., Helal C.J., Hou X., Hsu M.H., Johnson E.F., Lapham K., Lanyon L., Parris K., O’Neill B.T., Riddell D., Robshaw A., Vajdos F, & Brodney M.A. (2016). Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality. Journal of Medicinal Chemistry, 60(1), 386-402.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!