Mim 7

Manufactured by MIM Software

MIM 7.0.5 is a software application designed for medical imaging and analysis. It provides tools for visualizing and processing medical images, such as CT scans, MRI, and PET scans. The software supports a variety of file formats and includes features for image registration, segmentation, and quantitative analysis.

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Lab products found in correlation

Pet ct scanner, by Siemens (1 mentions)

Close spelling variants of this product

MIM version 7

2 protocols using mim 7

Quantifying Tumor Burden with PET/CT

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All patients had baseline ¹⁸F-FDG PET/CT scans before lymphodepletion and CD30.CAR-T cell infusion. In patients who had a ¹⁸F-FDG PET/CT prior to bridging therapy, these scans were evaluated for MTV to provide a tumor burden comparison before and after bridging therapy. ¹⁸F-FDG PET/CT scans were evaluated using MIM 7.0.5 (MIM Software, Cleveland, OH). MTV was computed using the threshold tool in MIM with a threshold 41% of the maximum standardized uptake value (SUV), or SUVmax, as described elsewhere.^{10-14 (link)} The lesion was manually selected and the region of interest increased until all voxels at least 41% of the SUVmax (Figure 1). MTV for each patient was determined by summing the volumes of lesions with voxels at least 41% of the SUVmax.

Voorhees T.J., Zhao B., Oldan J., Hucks G., Khandani A., Dittus C., Smith J., Morrison J.K., Cheng C.J., Ivanova A., Park S., Shea T.C., Beaven A.W., Dotti G., Serody J., Savoldo B, & Grover N. (2022). Pretherapy metabolic tumor volume is associated with response to CD30 CAR T cells in Hodgkin lymphoma. Blood Advances, 6(4), 1255-1263.

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2-[18F]FDG PET/MRI and PET/CT Imaging Protocol

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Patients fasted for at least 6 h before the 2-[¹⁸F]FDG PET study. The serum glucose level was determined at the time of 2-[¹⁸F]FDG injection, and all patients demonstrated a glucose level below 120 mg/dL. 2-[¹⁸F]FDG PET imaging was performed at 60–70 min after intravenous administration of 3.7–5.2 MBq/kg (0.10–0.14 mCi/kg) of 2-[¹⁸F]FDG as recommended by SNMMI/EANM guidelines, using either a 3-T PET/MRI scanner (n = 20; Signa GE Healthcare, Milwaukee, Wis) and a PET/CT scanner (n = 3; Siemens, Malvern, PA). The PET data acquisition time was 3:30 min per bed position for the PET/MRI (89 slices per bed position) for 5–9 bed positions and 3 min per bed position for PET/CT (47 slices per bed position) in six bed positions with 11-slice overlap at the edge of the axial field of view.
PET images were reconstructed using the Ordered-Subset Expectation Maximization (OSEM) algorithm with 2 iterations and 32 subsets for PET/CT and with 2 iterations and 28 subsets for PET/MRI. A non-contrast-enhanced low dose CT and 2-point Dixon sequences were used for attenuation correction of PET/CT and PET/MRI images, respectively. The resultant attenuation-corrected 2-[¹⁸F]FDG PET images were color encoded using MIM software (MIM 7.0.5; MIM Software, Beachwood, Ohio) and fused with CT or MRI scans.

Salter-Cid L., Brunmark A., Li Y., Leturcq D., Peterson P.A., Jackson M.R, & Yang Y. (1999). Transferrin receptor is negatively modulated by the hemochromatosis protein HFE: Implications for cellular iron homeostasis. Proceedings of the National Academy of Sciences of the United States of America, 96(10), 5434-5439.

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