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Human1.2m duo custom v1 array beadchips

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The Human1.2M-Duo Custom_v1 Array BeadChips is a high-throughput microarray platform designed for genome-wide genotyping analysis. It provides comprehensive coverage of genetic markers across the human genome.

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BeadChips (68 citations) Custom array (11 citations) BeadChip arrays (6 citations)

2 protocols using human1.2m duo custom v1 array beadchips

1

Genetic Profiling of Lung Cancer in British Europeans

Cited 2 times
Check if the same lab product or an alternative is used in the 5 most similar protocols
This comprised 1,952 cases (1,166 male; mean age at diagnosis 57 years, SD 6) with pathologically confirmed lung cancer ascertained through the Genetic Lung Cancer Predisposition Study (GELCAPS) conducted between March 1999 and July 200448 (link). All cases were British residents and self-reported to be of European Ancestry. To ensure that data and samples were collected from bona fide lung cancer cases and avoid issues of bias from survivorship only incident cases with histologically or cytologically (only if not AD) confirmed primary disease were ascertained. Tumours from patients were classified according to ICD-O3; Specifically, SQ: 8070/3, 8071/3, 8072/3, 8074/3; AD: 8140/3, 8250/3, 8260/3, 8310/3, 8480/3, 8560/3, 8251/3, 8490/3, 8570/3, 8574/3; with tumours with overlapping histologies classified as mixed. Patient DNA was derived from EDTA-venous blood samples using conventional methodologies. Genotype frequencies were compared with publicly accessible data generated by the UK Wellcome Trust Case-Control Consortium 2 (WTCCC2) study49 (link) of individuals from the 1958 British Birth Cohort (58BC) and blood service typed using Illumina Human1.2M-Duo Custom_v1 Array BeadChips.
Wang Y., McKay J.D., Rafnar T., Wang Z., Timofeeva M., Broderick P., Zong X., Laplana M., Wei Y., Han Y., Lloyd A., Delahaye-Sourdeix M., Chubb D., Gaborieau V., Wheeler W., Chatterjee N., Thorleifsson G., Sulem P., Liu G., Kaaks R., Henrion M., Kinnersley B., Vallée M., LeCalvez-Kelm F., Stevens V.L., Gapstur S.M., Chen W.V., Zaridze D., Szeszenia-Dabrowska N., Lissowska J., Rudnai P., Fabianova E., Mates D., Bencko V., Foretova L., Janout V., Krokan H.E., Gabrielsen M.E., Skorpen F., Vatten L., Njølstad I., Chen C., Goodman G., Benhamou S., Vooder T., Valk K., Nelis M., Metspalu A., Lener M., Lubiński J., Johansson M., Vineis P., Agudo A., Clavel-Chapelon F., Bueno-de-Mesquita H.B., Trichopoulos D., Khaw K.T., Johansson M., Weiderpass E., Tjønneland A., Riboli E., Lathrop M., Scelo G., Albanes D., Caporaso N.E., Ye Y., Gu J., Wu X., Spitz M.R., Dienemann H., Rosenberger A., Su L., Matakidou A., Eisen T., Stefansson K., Risch A., Chanock S.J., Christiani D.C., Hung R.J., Brennan P., Landi M.T., Houlston R.S, & Amos C.I. (2014). Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. Nature genetics, 46(7), 736-741.
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2

Genetic Profiling of Lung Cancer in British Europeans

Cited 2 times
Check if the same lab product or an alternative is used in the 5 most similar protocols
This comprised 1,952 cases (1,166 male; mean age at diagnosis 57 years, SD 6) with pathologically confirmed lung cancer ascertained through the Genetic Lung Cancer Predisposition Study (GELCAPS) conducted between March 1999 and July 200448 (link). All cases were British residents and self-reported to be of European Ancestry. To ensure that data and samples were collected from bona fide lung cancer cases and avoid issues of bias from survivorship only incident cases with histologically or cytologically (only if not AD) confirmed primary disease were ascertained. Tumours from patients were classified according to ICD-O3; Specifically, SQ: 8070/3, 8071/3, 8072/3, 8074/3; AD: 8140/3, 8250/3, 8260/3, 8310/3, 8480/3, 8560/3, 8251/3, 8490/3, 8570/3, 8574/3; with tumours with overlapping histologies classified as mixed. Patient DNA was derived from EDTA-venous blood samples using conventional methodologies. Genotype frequencies were compared with publicly accessible data generated by the UK Wellcome Trust Case-Control Consortium 2 (WTCCC2) study49 (link) of individuals from the 1958 British Birth Cohort (58BC) and blood service typed using Illumina Human1.2M-Duo Custom_v1 Array BeadChips.
Wang Y., McKay J.D., Rafnar T., Wang Z., Timofeeva M., Broderick P., Zong X., Laplana M., Wei Y., Han Y., Lloyd A., Delahaye-Sourdeix M., Chubb D., Gaborieau V., Wheeler W., Chatterjee N., Thorleifsson G., Sulem P., Liu G., Kaaks R., Henrion M., Kinnersley B., Vallée M., LeCalvez-Kelm F., Stevens V.L., Gapstur S.M., Chen W.V., Zaridze D., Szeszenia-Dabrowska N., Lissowska J., Rudnai P., Fabianova E., Mates D., Bencko V., Foretova L., Janout V., Krokan H.E., Gabrielsen M.E., Skorpen F., Vatten L., Njølstad I., Chen C., Goodman G., Benhamou S., Vooder T., Valk K., Nelis M., Metspalu A., Lener M., Lubiński J., Johansson M., Vineis P., Agudo A., Clavel-Chapelon F., Bueno-de-Mesquita H.B., Trichopoulos D., Khaw K.T., Johansson M., Weiderpass E., Tjønneland A., Riboli E., Lathrop M., Scelo G., Albanes D., Caporaso N.E., Ye Y., Gu J., Wu X., Spitz M.R., Dienemann H., Rosenberger A., Su L., Matakidou A., Eisen T., Stefansson K., Risch A., Chanock S.J., Christiani D.C., Hung R.J., Brennan P., Landi M.T., Houlston R.S, & Amos C.I. (2014). Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer. Nature genetics, 46(7), 736-741.
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